Chemistry of xanthorrhizol: synthesis of several bisabolane sesquiterpenoids from xanthorrhizol
Abstract—()-Xanthorrhizol (1) isolated from the rhizomes of Curcuma xanthorrhiza has been transformed to several bisabolanetype sesquiterpenoids, in a stereoselective manner. 10R- and 10S-10,11-dihydro-10,11-dihydroxyxanthorrhizols (2, 3), ()-curcuquinone (4), ()-curcuhydroquinone (5), helibisab...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2007
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| Subjects: | |
| Online Access: | http://eprints.utm.my/2489/ http://eprints.utm.my/2489/1/HasnahMSirat2007_Chemistryofxanthorrhizolsynthesis.pdf |
| Summary: | Abstract—()-Xanthorrhizol (1) isolated from the rhizomes of Curcuma xanthorrhiza has been transformed to several bisabolanetype
sesquiterpenoids, in a stereoselective manner. 10R- and 10S-10,11-dihydro-10,11-dihydroxyxanthorrhizols (2, 3), ()-curcuquinone
(4), ()-curcuhydroquinone (5), helibisabonol A (7) and allylic alcohol 8 have been prepared from xanthorrhizol in optically
active forms. All the routes involved a Sharpless AD to introduce the stereogenic centre at C-10.
2006 Elsevier Ltd. All rights reserved. |
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