Performance Study Of Carbon-Clad Zirconia Stationary Phase In High Temperature Reversed-Phase High Performance Liquid Chromatography

The performance of carbon-clad zirconia (CCZ) stationary phase was evaluated for the separations of test compounds (benzaldehyde, benzamide, nitrobenzene, and toluene) and alkyl aryl ketones (acetophenone, propiophenone, butyrophenone and valerophenone) at high temperature (100ËšC-160ËšC) in reverse...

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Main Authors: Sanagi, Mohd. Marsin, See, Hong Heng, Francis, Jaclyn Ann
Format: Article
Language:English
Published: Penerbit UTM Press 2005
Subjects:
Online Access:http://eprints.utm.my/1388/
http://eprints.utm.my/1388/1/JTDIS43C2.pdf
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author Sanagi, Mohd. Marsin
See, Hong Heng
Francis, Jaclyn Ann
author_facet Sanagi, Mohd. Marsin
See, Hong Heng
Francis, Jaclyn Ann
author_sort Sanagi, Mohd. Marsin
building UTeM Institutional Repository
collection Online Access
description The performance of carbon-clad zirconia (CCZ) stationary phase was evaluated for the separations of test compounds (benzaldehyde, benzamide, nitrobenzene, and toluene) and alkyl aryl ketones (acetophenone, propiophenone, butyrophenone and valerophenone) at high temperature (100˚C-160˚C) in reversed-phase high performance liquid chromatography (RP-HPLC) using low compositions of organic modifier and 100% pure water as eluent. Improved separation mechanism and faster analysis time were achieved during high operating temperatures. Van’t Hoff plots were linear for the investigated CCZ column, which showed that over the temperature range, no changes occurred in the retention mechanism. The use of alkyl aryl ketone homologs as a retention index scale in high temperature RP-HPLC was investigated. Although the retention factors of the test compounds were greatly affected by increasing the column temperature, there were only slight variations in their respective retention index values.
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spelling utm-13882017-11-01T04:17:33Z http://eprints.utm.my/1388/ Performance Study Of Carbon-Clad Zirconia Stationary Phase In High Temperature Reversed-Phase High Performance Liquid Chromatography Sanagi, Mohd. Marsin See, Hong Heng Francis, Jaclyn Ann QD Chemistry The performance of carbon-clad zirconia (CCZ) stationary phase was evaluated for the separations of test compounds (benzaldehyde, benzamide, nitrobenzene, and toluene) and alkyl aryl ketones (acetophenone, propiophenone, butyrophenone and valerophenone) at high temperature (100˚C-160˚C) in reversed-phase high performance liquid chromatography (RP-HPLC) using low compositions of organic modifier and 100% pure water as eluent. Improved separation mechanism and faster analysis time were achieved during high operating temperatures. Van’t Hoff plots were linear for the investigated CCZ column, which showed that over the temperature range, no changes occurred in the retention mechanism. The use of alkyl aryl ketone homologs as a retention index scale in high temperature RP-HPLC was investigated. Although the retention factors of the test compounds were greatly affected by increasing the column temperature, there were only slight variations in their respective retention index values. Penerbit UTM Press 2005-12 Article PeerReviewed application/pdf en http://eprints.utm.my/1388/1/JTDIS43C2.pdf Sanagi, Mohd. Marsin and See, Hong Heng and Francis, Jaclyn Ann (2005) Performance Study Of Carbon-Clad Zirconia Stationary Phase In High Temperature Reversed-Phase High Performance Liquid Chromatography. Jurnal Teknologi C (43C). pp. 15-26. ISSN 0127-9696 http://www.jurnalteknologi.utm.my/index.php/jurnalteknologi/article/view/768
spellingShingle QD Chemistry
Sanagi, Mohd. Marsin
See, Hong Heng
Francis, Jaclyn Ann
Performance Study Of Carbon-Clad Zirconia Stationary Phase In High Temperature Reversed-Phase High Performance Liquid Chromatography
title Performance Study Of Carbon-Clad Zirconia Stationary Phase In High Temperature Reversed-Phase High Performance Liquid Chromatography
title_full Performance Study Of Carbon-Clad Zirconia Stationary Phase In High Temperature Reversed-Phase High Performance Liquid Chromatography
title_fullStr Performance Study Of Carbon-Clad Zirconia Stationary Phase In High Temperature Reversed-Phase High Performance Liquid Chromatography
title_full_unstemmed Performance Study Of Carbon-Clad Zirconia Stationary Phase In High Temperature Reversed-Phase High Performance Liquid Chromatography
title_short Performance Study Of Carbon-Clad Zirconia Stationary Phase In High Temperature Reversed-Phase High Performance Liquid Chromatography
title_sort performance study of carbon-clad zirconia stationary phase in high temperature reversed-phase high performance liquid chromatography
topic QD Chemistry
url http://eprints.utm.my/1388/
http://eprints.utm.my/1388/
http://eprints.utm.my/1388/1/JTDIS43C2.pdf