Phytochemical analysis and in-vitro antiurolithiatic properties of selected Malaysian herbs
The aim of this study was to investigate the phytochemical content of selected Malaysian herbs and their potential antiurolithiatic effects using in-vitro method. The herbs involved are Ceiba pentandra, Cymbopogon citratus, Euphorbia hirta, Melastoma malabathricum and Ortosiphon stamineus. Aqueou...
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| Format: | Article |
| Language: | English |
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Penerbit Akademia Baru
2019
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| Online Access: | http://eprints.uthm.edu.my/813/ http://eprints.uthm.edu.my/813/1/DNJ9787_9ac7ec6f6d09160f75d9006881f41800.pdf |
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| author | Wan Marzuki Rashidi, Wan Nur Ain Syukriah Muhammad, Norhayati Sairi, Nur Halimah Abdul Rahim, Nur Fazira A. Talip, Balkis Abdullah, Norazlin Abu Bakar, Mohd Fadzelly |
| author_facet | Wan Marzuki Rashidi, Wan Nur Ain Syukriah Muhammad, Norhayati Sairi, Nur Halimah Abdul Rahim, Nur Fazira A. Talip, Balkis Abdullah, Norazlin Abu Bakar, Mohd Fadzelly |
| author_sort | Wan Marzuki Rashidi, Wan Nur Ain Syukriah |
| building | UTHM Institutional Repository |
| collection | Online Access |
| description | The aim of this study was to investigate the phytochemical content of selected
Malaysian herbs and their potential antiurolithiatic effects using in-vitro method. The
herbs involved are Ceiba pentandra, Cymbopogon citratus, Euphorbia hirta,
Melastoma malabathricum and Ortosiphon stamineus. Aqueous extracts of each herbs
were prepared through decoction while Standard drugs Cystone, was used as positive
control in comparison. Qualitative analysis was carried out to detect phytochemical
presence and nucleation assay to investigate their inhibition effects towards calcium
oxalate crystallization urolithiasis in vitro. Based on results, the same trends were
observed between phytochemical content and inhibition rate of calcium oxalate
crystallization. O. stamineus extract (73.48%) which showed the highest inhibition rate
hold the most phytochemical content. while the lowest inhibition rate was occupied
by C. citratus extract (45.45%) with the least phytochemical content. The high amount
of phytochemicals particularly saponin followed by steroid and terpenoid in O.
stamineus extract might contributes to the high inhibition activities of calcium oxalate
crystallization as compared to low amount of phytochemicals observed in C. citratus
extract. It can be concluded that O. stamineus possesses highest inhibition percentage
against calcium oxalate which could be attributed to its saponins, tannins, steroid and
terpenoid content. |
| first_indexed | 2025-11-15T19:52:12Z |
| format | Article |
| id | uthm-813 |
| institution | Universiti Tun Hussein Onn Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T19:52:12Z |
| publishDate | 2019 |
| publisher | Penerbit Akademia Baru |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | uthm-8132021-10-17T07:01:48Z http://eprints.uthm.edu.my/813/ Phytochemical analysis and in-vitro antiurolithiatic properties of selected Malaysian herbs Wan Marzuki Rashidi, Wan Nur Ain Syukriah Muhammad, Norhayati Sairi, Nur Halimah Abdul Rahim, Nur Fazira A. Talip, Balkis Abdullah, Norazlin Abu Bakar, Mohd Fadzelly QH Natural history The aim of this study was to investigate the phytochemical content of selected Malaysian herbs and their potential antiurolithiatic effects using in-vitro method. The herbs involved are Ceiba pentandra, Cymbopogon citratus, Euphorbia hirta, Melastoma malabathricum and Ortosiphon stamineus. Aqueous extracts of each herbs were prepared through decoction while Standard drugs Cystone, was used as positive control in comparison. Qualitative analysis was carried out to detect phytochemical presence and nucleation assay to investigate their inhibition effects towards calcium oxalate crystallization urolithiasis in vitro. Based on results, the same trends were observed between phytochemical content and inhibition rate of calcium oxalate crystallization. O. stamineus extract (73.48%) which showed the highest inhibition rate hold the most phytochemical content. while the lowest inhibition rate was occupied by C. citratus extract (45.45%) with the least phytochemical content. The high amount of phytochemicals particularly saponin followed by steroid and terpenoid in O. stamineus extract might contributes to the high inhibition activities of calcium oxalate crystallization as compared to low amount of phytochemicals observed in C. citratus extract. It can be concluded that O. stamineus possesses highest inhibition percentage against calcium oxalate which could be attributed to its saponins, tannins, steroid and terpenoid content. Penerbit Akademia Baru 2019 Article PeerReviewed text en http://eprints.uthm.edu.my/813/1/DNJ9787_9ac7ec6f6d09160f75d9006881f41800.pdf Wan Marzuki Rashidi, Wan Nur Ain Syukriah and Muhammad, Norhayati and Sairi, Nur Halimah and Abdul Rahim, Nur Fazira and A. Talip, Balkis and Abdullah, Norazlin and Abu Bakar, Mohd Fadzelly (2019) Phytochemical analysis and in-vitro antiurolithiatic properties of selected Malaysian herbs. Journal of Advanced Research in Fluid Mechanics and Thermal Sciences, 64 (1). pp. 152-159. ISSN 2289-7879 |
| spellingShingle | QH Natural history Wan Marzuki Rashidi, Wan Nur Ain Syukriah Muhammad, Norhayati Sairi, Nur Halimah Abdul Rahim, Nur Fazira A. Talip, Balkis Abdullah, Norazlin Abu Bakar, Mohd Fadzelly Phytochemical analysis and in-vitro antiurolithiatic properties of selected Malaysian herbs |
| title | Phytochemical analysis and in-vitro antiurolithiatic properties of selected Malaysian herbs |
| title_full | Phytochemical analysis and in-vitro antiurolithiatic properties of selected Malaysian herbs |
| title_fullStr | Phytochemical analysis and in-vitro antiurolithiatic properties of selected Malaysian herbs |
| title_full_unstemmed | Phytochemical analysis and in-vitro antiurolithiatic properties of selected Malaysian herbs |
| title_short | Phytochemical analysis and in-vitro antiurolithiatic properties of selected Malaysian herbs |
| title_sort | phytochemical analysis and in-vitro antiurolithiatic properties of selected malaysian herbs |
| topic | QH Natural history |
| url | http://eprints.uthm.edu.my/813/ http://eprints.uthm.edu.my/813/1/DNJ9787_9ac7ec6f6d09160f75d9006881f41800.pdf |