Preparation of the electrospun polyvinylidene fluoride / polyvinyl alcohol scaffold as a potential tissue replacement
Polyvinylidene fluoride (PVDF), a piezoelectric material, is commonly used in tissue engineering due to its potential for mimicking the electrical microenvironment of biological conditions for tissue development. In this present research, polyvinyl alcohol (PVA) was introduced into electrospun PVDF...
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| Format: | Article |
| Language: | English |
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IIUM Press
2020
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| Online Access: | http://eprints.uthm.edu.my/6332/ http://eprints.uthm.edu.my/6332/1/J12969_daad44e303b91e668e10ccf78c540741.pdf |
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| author | Hamzah, Mohd Syahir Anwar Ab Razak, Nurul Amira Ng, Celine Abdul Azize, Akmal Hafiszi Abdul Sukor, Jumadi Soon, Chin Fhong Idris, Mohd Safiee Mat Nayan, Nadirul Hasraf |
| author_facet | Hamzah, Mohd Syahir Anwar Ab Razak, Nurul Amira Ng, Celine Abdul Azize, Akmal Hafiszi Abdul Sukor, Jumadi Soon, Chin Fhong Idris, Mohd Safiee Mat Nayan, Nadirul Hasraf |
| author_sort | Hamzah, Mohd Syahir Anwar |
| building | UTHM Institutional Repository |
| collection | Online Access |
| description | Polyvinylidene fluoride (PVDF), a piezoelectric material, is commonly used in tissue engineering due to its potential for mimicking the electrical microenvironment of biological conditions for tissue development. In this present research, polyvinyl alcohol (PVA) was introduced into electrospun PVDF fabrication through an electrospinning process, aiming to enhance the nanofibrous membrane's biocompatibility properties by improving the hydrophilicity properties to act as an artificial tissue scaffold. The electrospun PVDF/PVA membranes are found to be optimum at a PVDF-to-PVA ratio of 90:10 due to its excellent mechanical, morphological, and hydrophilicity conductivity properties. Fourier transform infrared (FTIR) spectroscopy verified strong hydrogen bonding interaction formed between the fluorine group of PVDF with oxygen-containing in the hydroxyl group of PVA. In-vitro cell culture showed that the enhanced hydrophilic property of electrospun PVDF/PVA could significantly enhance the cell growth. These positive results indicated that the scaffold could be implemented as artificial tissue material for tissue engineering applications. |
| first_indexed | 2025-11-15T20:15:44Z |
| format | Article |
| id | uthm-6332 |
| institution | Universiti Tun Hussein Onn Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T20:15:44Z |
| publishDate | 2020 |
| publisher | IIUM Press |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | uthm-63322022-01-30T03:16:06Z http://eprints.uthm.edu.my/6332/ Preparation of the electrospun polyvinylidene fluoride / polyvinyl alcohol scaffold as a potential tissue replacement Hamzah, Mohd Syahir Anwar Ab Razak, Nurul Amira Ng, Celine Abdul Azize, Akmal Hafiszi Abdul Sukor, Jumadi Soon, Chin Fhong Idris, Mohd Safiee Mat Nayan, Nadirul Hasraf TP250-261 Industrial electrochemistry Polyvinylidene fluoride (PVDF), a piezoelectric material, is commonly used in tissue engineering due to its potential for mimicking the electrical microenvironment of biological conditions for tissue development. In this present research, polyvinyl alcohol (PVA) was introduced into electrospun PVDF fabrication through an electrospinning process, aiming to enhance the nanofibrous membrane's biocompatibility properties by improving the hydrophilicity properties to act as an artificial tissue scaffold. The electrospun PVDF/PVA membranes are found to be optimum at a PVDF-to-PVA ratio of 90:10 due to its excellent mechanical, morphological, and hydrophilicity conductivity properties. Fourier transform infrared (FTIR) spectroscopy verified strong hydrogen bonding interaction formed between the fluorine group of PVDF with oxygen-containing in the hydroxyl group of PVA. In-vitro cell culture showed that the enhanced hydrophilic property of electrospun PVDF/PVA could significantly enhance the cell growth. These positive results indicated that the scaffold could be implemented as artificial tissue material for tissue engineering applications. IIUM Press 2020 Article PeerReviewed text en http://eprints.uthm.edu.my/6332/1/J12969_daad44e303b91e668e10ccf78c540741.pdf Hamzah, Mohd Syahir Anwar and Ab Razak, Nurul Amira and Ng, Celine and Abdul Azize, Akmal Hafiszi and Abdul Sukor, Jumadi and Soon, Chin Fhong and Idris, Mohd Safiee and Mat Nayan, Nadirul Hasraf (2020) Preparation of the electrospun polyvinylidene fluoride / polyvinyl alcohol scaffold as a potential tissue replacement. IIUM Engineering Journal, 22 (1). ISSN 1511-758x https://doi.org/10.31436/iiumej.v22i1.1548 |
| spellingShingle | TP250-261 Industrial electrochemistry Hamzah, Mohd Syahir Anwar Ab Razak, Nurul Amira Ng, Celine Abdul Azize, Akmal Hafiszi Abdul Sukor, Jumadi Soon, Chin Fhong Idris, Mohd Safiee Mat Nayan, Nadirul Hasraf Preparation of the electrospun polyvinylidene fluoride / polyvinyl alcohol scaffold as a potential tissue replacement |
| title | Preparation of the electrospun polyvinylidene fluoride / polyvinyl alcohol scaffold as a potential tissue replacement |
| title_full | Preparation of the electrospun polyvinylidene fluoride / polyvinyl alcohol scaffold as a potential tissue replacement |
| title_fullStr | Preparation of the electrospun polyvinylidene fluoride / polyvinyl alcohol scaffold as a potential tissue replacement |
| title_full_unstemmed | Preparation of the electrospun polyvinylidene fluoride / polyvinyl alcohol scaffold as a potential tissue replacement |
| title_short | Preparation of the electrospun polyvinylidene fluoride / polyvinyl alcohol scaffold as a potential tissue replacement |
| title_sort | preparation of the electrospun polyvinylidene fluoride / polyvinyl alcohol scaffold as a potential tissue replacement |
| topic | TP250-261 Industrial electrochemistry |
| url | http://eprints.uthm.edu.my/6332/ http://eprints.uthm.edu.my/6332/ http://eprints.uthm.edu.my/6332/1/J12969_daad44e303b91e668e10ccf78c540741.pdf |