Parametric frailty model with time-dependent covariates

The parametric frailty model has been used in this study where, the term frailty is used to represent an unobservable random effect shared by subjects with similar (unmeasured) risks in the analysis of mortality rate. In real-life environment, the application of frailty models have been widely used...

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Main Authors: Abdullah, Mohd Asrul Affendi, Zaimi, Emir Mukhriz, Muhamad Jamil, Siti Afiqah
Format: Article
Published: Blue Eyes Intelligence Engineering & Sciences Publication 2020
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Online Access:http://eprints.uthm.edu.my/5088/
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author Abdullah, Mohd Asrul Affendi
Zaimi, Emir Mukhriz
Muhamad Jamil, Siti Afiqah
author_facet Abdullah, Mohd Asrul Affendi
Zaimi, Emir Mukhriz
Muhamad Jamil, Siti Afiqah
author_sort Abdullah, Mohd Asrul Affendi
building UTHM Institutional Repository
collection Online Access
description The parametric frailty model has been used in this study where, the term frailty is used to represent an unobservable random effect shared by subjects with similar (unmeasured) risks in the analysis of mortality rate. In real-life environment, the application of frailty models have been widely used by biostatistician, economists and epidemiologist to donate proneness to disease, accidents and other events because there are persistent differences in susceptibility among individuals. When heterogeneity is ignored in a study of survival analysis the result will produce an incorrect estimation of parameters and standard errors. This study used gamma and Weibull distribution for the frailty model. The first objective of this study is to investigate parametric model with time dependent covariates on frailty model. The derivation is using either classical maximum likelihood or Monte Carlo integration. The second objective is to measure the effectiveness of Gamma and Weibull frailty model with and without time-dependent covariates. This is done by calculating the root mean square error (RMSE). The last objective is to assess the goodness of fit of Gamma and Weibull frailty model with and without time-dependent covariates using Akaike Information Criterion (AIC) and Bayesian Information Criterion (BIC). Simulation is used in order to obtain the RMSE, AIC ad BIC value if time-dependent covariate does not exists. Between both models with time-dependent covariate, Weibull frailty distribution has lower AIC and BIC compared to Gamma frailty distribution. Therefore, Weibull frailty distribution with time-dependent covariate is preferable when a time-dependent covariate exists in a data.
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spelling uthm-50882022-01-05T06:25:45Z http://eprints.uthm.edu.my/5088/ Parametric frailty model with time-dependent covariates Abdullah, Mohd Asrul Affendi Zaimi, Emir Mukhriz Muhamad Jamil, Siti Afiqah QA273-280 Probabilities. Mathematical statistics The parametric frailty model has been used in this study where, the term frailty is used to represent an unobservable random effect shared by subjects with similar (unmeasured) risks in the analysis of mortality rate. In real-life environment, the application of frailty models have been widely used by biostatistician, economists and epidemiologist to donate proneness to disease, accidents and other events because there are persistent differences in susceptibility among individuals. When heterogeneity is ignored in a study of survival analysis the result will produce an incorrect estimation of parameters and standard errors. This study used gamma and Weibull distribution for the frailty model. The first objective of this study is to investigate parametric model with time dependent covariates on frailty model. The derivation is using either classical maximum likelihood or Monte Carlo integration. The second objective is to measure the effectiveness of Gamma and Weibull frailty model with and without time-dependent covariates. This is done by calculating the root mean square error (RMSE). The last objective is to assess the goodness of fit of Gamma and Weibull frailty model with and without time-dependent covariates using Akaike Information Criterion (AIC) and Bayesian Information Criterion (BIC). Simulation is used in order to obtain the RMSE, AIC ad BIC value if time-dependent covariate does not exists. Between both models with time-dependent covariate, Weibull frailty distribution has lower AIC and BIC compared to Gamma frailty distribution. Therefore, Weibull frailty distribution with time-dependent covariate is preferable when a time-dependent covariate exists in a data. Blue Eyes Intelligence Engineering & Sciences Publication 2020 Article PeerReviewed Abdullah, Mohd Asrul Affendi and Zaimi, Emir Mukhriz and Muhamad Jamil, Siti Afiqah (2020) Parametric frailty model with time-dependent covariates. International Journal of Recent Technology and Engineering (IJRTE), 8 (5). pp. 952-956. ISSN 2277-3878 https://dx.doi.org/10.35940/ijrte.D7625.018520
spellingShingle QA273-280 Probabilities. Mathematical statistics
Abdullah, Mohd Asrul Affendi
Zaimi, Emir Mukhriz
Muhamad Jamil, Siti Afiqah
Parametric frailty model with time-dependent covariates
title Parametric frailty model with time-dependent covariates
title_full Parametric frailty model with time-dependent covariates
title_fullStr Parametric frailty model with time-dependent covariates
title_full_unstemmed Parametric frailty model with time-dependent covariates
title_short Parametric frailty model with time-dependent covariates
title_sort parametric frailty model with time-dependent covariates
topic QA273-280 Probabilities. Mathematical statistics
url http://eprints.uthm.edu.my/5088/
http://eprints.uthm.edu.my/5088/