Visualisation on blood flow mechanism of vein in deep vein thrombosis (DVT) study

Blood velocity is expected to be a parameter for detecting blood abnormality, for example the existence of thrombus. Proper blood flow in veins are important to ensure the effective return of deoxygenated blood to the heart. It is challenging to determine the vessel condition, due to the inability t...

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Main Author: Aziz, Nur Shazilah
Format: Thesis
Language:English
English
English
Published: 2018
Subjects:
Online Access:http://eprints.uthm.edu.my/240/
http://eprints.uthm.edu.my/240/1/24p%20NUR%20SHAZILAH%20BT%20AZIZ.pdf
http://eprints.uthm.edu.my/240/2/NUR%20SHAZILAH%20BT%20AZIZ%20COPYRIGHT%20DECLARATION.pdf
http://eprints.uthm.edu.my/240/3/NUR%20SHAZILAH%20BT%20AZIZ%20WATERMARK.pdf
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author Aziz, Nur Shazilah
author_facet Aziz, Nur Shazilah
author_sort Aziz, Nur Shazilah
building UTHM Institutional Repository
collection Online Access
description Blood velocity is expected to be a parameter for detecting blood abnormality, for example the existence of thrombus. Proper blood flow in veins are important to ensure the effective return of deoxygenated blood to the heart. It is challenging to determine the vessel condition, due to the inability to visualize the thrombus presence in the vessel. This is due to the noise that are present in the image obtained from Ultrasound scanning. Since it is difficult to recognize the vessel condition at the earliest stage of Deep Vein Thrombosis (DVT), this study aims to assess the velocity and vorticity at the valve region using the Computational Fluid Dynamics (CFD) method. The velocity ofblood and the size of valve orifice are considered important parameters in designing the vein. Following Virchow's triad theory, the stenosis and irregularities of velocity in the blood vessel are known as the risk factors for thrombus formation. This study also includes the effect of different sizes of valve orifice with the existence of 1 mm and 3 mm thrombus, as both represent the DVT condition. From the simulation, the velocity contour plot of the blood flow can be visualised clearly. The blood distribution was presented using velocity profile while the fluid particles movement was shown by velocity vector. Vorticity contour meanwhile provides information on the tendency of particles to move in circular motion. Based on the simulation, the low blood velocity clearly shows the low velocity region which resides at the cusps area and at the beginning of the valve leaflets. Therefore, the present study has successfully shown that the CFD method is able to determine and evaluate the probable location of thrombus development in the blood vessel.
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format Thesis
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institution Universiti Tun Hussein Onn Malaysia
institution_category Local University
language English
English
English
last_indexed 2025-11-15T19:49:35Z
publishDate 2018
recordtype eprints
repository_type Digital Repository
spelling uthm-2402021-07-13T03:23:27Z http://eprints.uthm.edu.my/240/ Visualisation on blood flow mechanism of vein in deep vein thrombosis (DVT) study Aziz, Nur Shazilah TK8300-8360 Photoelectronic devices (General) Blood velocity is expected to be a parameter for detecting blood abnormality, for example the existence of thrombus. Proper blood flow in veins are important to ensure the effective return of deoxygenated blood to the heart. It is challenging to determine the vessel condition, due to the inability to visualize the thrombus presence in the vessel. This is due to the noise that are present in the image obtained from Ultrasound scanning. Since it is difficult to recognize the vessel condition at the earliest stage of Deep Vein Thrombosis (DVT), this study aims to assess the velocity and vorticity at the valve region using the Computational Fluid Dynamics (CFD) method. The velocity ofblood and the size of valve orifice are considered important parameters in designing the vein. Following Virchow's triad theory, the stenosis and irregularities of velocity in the blood vessel are known as the risk factors for thrombus formation. This study also includes the effect of different sizes of valve orifice with the existence of 1 mm and 3 mm thrombus, as both represent the DVT condition. From the simulation, the velocity contour plot of the blood flow can be visualised clearly. The blood distribution was presented using velocity profile while the fluid particles movement was shown by velocity vector. Vorticity contour meanwhile provides information on the tendency of particles to move in circular motion. Based on the simulation, the low blood velocity clearly shows the low velocity region which resides at the cusps area and at the beginning of the valve leaflets. Therefore, the present study has successfully shown that the CFD method is able to determine and evaluate the probable location of thrombus development in the blood vessel. 2018-05 Thesis NonPeerReviewed text en http://eprints.uthm.edu.my/240/1/24p%20NUR%20SHAZILAH%20BT%20AZIZ.pdf text en http://eprints.uthm.edu.my/240/2/NUR%20SHAZILAH%20BT%20AZIZ%20COPYRIGHT%20DECLARATION.pdf text en http://eprints.uthm.edu.my/240/3/NUR%20SHAZILAH%20BT%20AZIZ%20WATERMARK.pdf Aziz, Nur Shazilah (2018) Visualisation on blood flow mechanism of vein in deep vein thrombosis (DVT) study. Masters thesis, Universiti Tun Hussein Onn Malaysia.
spellingShingle TK8300-8360 Photoelectronic devices (General)
Aziz, Nur Shazilah
Visualisation on blood flow mechanism of vein in deep vein thrombosis (DVT) study
title Visualisation on blood flow mechanism of vein in deep vein thrombosis (DVT) study
title_full Visualisation on blood flow mechanism of vein in deep vein thrombosis (DVT) study
title_fullStr Visualisation on blood flow mechanism of vein in deep vein thrombosis (DVT) study
title_full_unstemmed Visualisation on blood flow mechanism of vein in deep vein thrombosis (DVT) study
title_short Visualisation on blood flow mechanism of vein in deep vein thrombosis (DVT) study
title_sort visualisation on blood flow mechanism of vein in deep vein thrombosis (dvt) study
topic TK8300-8360 Photoelectronic devices (General)
url http://eprints.uthm.edu.my/240/
http://eprints.uthm.edu.my/240/1/24p%20NUR%20SHAZILAH%20BT%20AZIZ.pdf
http://eprints.uthm.edu.my/240/2/NUR%20SHAZILAH%20BT%20AZIZ%20COPYRIGHT%20DECLARATION.pdf
http://eprints.uthm.edu.my/240/3/NUR%20SHAZILAH%20BT%20AZIZ%20WATERMARK.pdf