Pathophysiology, histopathology and therapeutic of SARS-CoV-2
The rapid transmission of SARS-CoV-2 through the world has induced the scientist to understand the histopathology of the virus and then to find an effective drug. However, many of the point associated with the virus pathogenicity still unknown and need more studies. In this chapter the pathophysiolo...
| Main Authors: | , , , , , , |
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| Other Authors: | |
| Format: | Book Section |
| Language: | English |
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Penerbit UTHM
2020
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| Subjects: | |
| Online Access: | http://eprints.uthm.edu.my/2255/ http://eprints.uthm.edu.my/2255/1/ch04.pdf |
| _version_ | 1848887688178958336 |
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| author | Noman, Efaq Al-Gheethi, Adel Radin Mohamed, Radin Maya Saphira Al-Shorgani, Najeeb Talip, Balkis Hezam, Kamal Othman, Norzila |
| author2 | Al-Gheethi, Adel Ali Saeed |
| author_facet | Al-Gheethi, Adel Ali Saeed Noman, Efaq Al-Gheethi, Adel Radin Mohamed, Radin Maya Saphira Al-Shorgani, Najeeb Talip, Balkis Hezam, Kamal Othman, Norzila |
| author_sort | Noman, Efaq |
| building | UTHM Institutional Repository |
| collection | Online Access |
| description | The rapid transmission of SARS-CoV-2 through the world has induced the scientist to understand the histopathology of the virus and then to find an effective drug. However, many of the point associated with the virus pathogenicity still unknown and need more studies. In this chapter the pathophysiology, histopathology and therapeutic of SARS-CoV-2 has been reviewed. It was appeared that pathogenicity of SARS-CoV-2 is belonging to the viral with genome structure which acting by blocking the host innate immune response. Both chloroquine and hydroxyl-chloroquine have similar structure and mechanism action and they are among the most effective antiviral for treating the patents with the SARS-CoV-2. Chloroquine works by inhibition the intracellular organism by increasing the pH. |
| first_indexed | 2025-11-15T19:58:22Z |
| format | Book Section |
| id | uthm-2255 |
| institution | Universiti Tun Hussein Onn Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T19:58:22Z |
| publishDate | 2020 |
| publisher | Penerbit UTHM |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | uthm-22552021-11-02T03:47:46Z http://eprints.uthm.edu.my/2255/ Pathophysiology, histopathology and therapeutic of SARS-CoV-2 Noman, Efaq Al-Gheethi, Adel Radin Mohamed, Radin Maya Saphira Al-Shorgani, Najeeb Talip, Balkis Hezam, Kamal Othman, Norzila RA Public aspects of medicine The rapid transmission of SARS-CoV-2 through the world has induced the scientist to understand the histopathology of the virus and then to find an effective drug. However, many of the point associated with the virus pathogenicity still unknown and need more studies. In this chapter the pathophysiology, histopathology and therapeutic of SARS-CoV-2 has been reviewed. It was appeared that pathogenicity of SARS-CoV-2 is belonging to the viral with genome structure which acting by blocking the host innate immune response. Both chloroquine and hydroxyl-chloroquine have similar structure and mechanism action and they are among the most effective antiviral for treating the patents with the SARS-CoV-2. Chloroquine works by inhibition the intracellular organism by increasing the pH. Penerbit UTHM Al-Gheethi, Adel Ali Saeed Radin Mohamed, Radin Maya Saphira Ali Noman, Efaq 2020 Book Section PeerReviewed text en http://eprints.uthm.edu.my/2255/1/ch04.pdf Noman, Efaq and Al-Gheethi, Adel and Radin Mohamed, Radin Maya Saphira and Al-Shorgani, Najeeb and Talip, Balkis and Hezam, Kamal and Othman, Norzila (2020) Pathophysiology, histopathology and therapeutic of SARS-CoV-2. In: Covid-19 Pandemic. Penerbit UTHM, pp. 64-76. ISBN 978-967-2389-64-4 |
| spellingShingle | RA Public aspects of medicine Noman, Efaq Al-Gheethi, Adel Radin Mohamed, Radin Maya Saphira Al-Shorgani, Najeeb Talip, Balkis Hezam, Kamal Othman, Norzila Pathophysiology, histopathology and therapeutic of SARS-CoV-2 |
| title | Pathophysiology, histopathology and therapeutic of SARS-CoV-2 |
| title_full | Pathophysiology, histopathology and therapeutic of SARS-CoV-2 |
| title_fullStr | Pathophysiology, histopathology and therapeutic of SARS-CoV-2 |
| title_full_unstemmed | Pathophysiology, histopathology and therapeutic of SARS-CoV-2 |
| title_short | Pathophysiology, histopathology and therapeutic of SARS-CoV-2 |
| title_sort | pathophysiology, histopathology and therapeutic of sars-cov-2 |
| topic | RA Public aspects of medicine |
| url | http://eprints.uthm.edu.my/2255/ http://eprints.uthm.edu.my/2255/1/ch04.pdf |