Application of a new choline-imidazole based deep eutectic solvents in hybrid magnetic molecularly imprinted polymer for efficient and selective removal of naproxen from aqueous samples
A magnetic molecularly imprinted polymer (Fe3O4@MIP) with naproxen (as template) was successfully prepared by adding a co-solvent consisting of a choline-imidazole based deep eutectic solvent (ChCl-BuIM) during polymerisation. The morphological, functional group, and magnetic characteristics of th...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2021
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| Online Access: | http://eprints.uthm.edu.my/1037/ http://eprints.uthm.edu.my/1037/1/J11948_bef6a747948caa54502eec437e9dd1b2.pdf |
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| author | Husin, Nor Aniisah Muhamad, Musthahimah Yahaya, Noorfatimah Miskam, Mazidatulakmam Nik Mohamed Kamal, Nik Nur Syazni Asman, Saliza Raoov, Muggundha Mohamad Zain, Nur Nadhirah |
| author_facet | Husin, Nor Aniisah Muhamad, Musthahimah Yahaya, Noorfatimah Miskam, Mazidatulakmam Nik Mohamed Kamal, Nik Nur Syazni Asman, Saliza Raoov, Muggundha Mohamad Zain, Nur Nadhirah |
| author_sort | Husin, Nor Aniisah |
| building | UTHM Institutional Repository |
| collection | Online Access |
| description | A magnetic molecularly imprinted polymer (Fe3O4@MIP) with naproxen (as template) was successfully prepared
by adding a co-solvent consisting of a choline-imidazole based deep eutectic solvent (ChCl-BuIM) during polymerisation.
The morphological, functional group, and magnetic characteristics of the synthesised materials were
characterised by elemental analysis, Fourier transform-infrared spectroscopy, scanning electron microscopy, and
vibrating sample magnetometer. This hybrid Fe3O4@MIP-ChCl-BuIM material was used as a magnetic adsorbent
for efficient and selective removal of naproxen from wastewater samples. A batch adsorption study showed that
adsorption of naproxen onto the multilayer surface of the adsorbent through a chemisorption mechanism. The
data showed that the adsorption was feasible, spontaneous, and exothermic. The Fe3O4@MIP-ChCl-BuIM
removed more naproxen (93.2–97.1%) than Fe3O4@MIP without ChCl-BuIM (83.2–88.9%). This finding confirms
that the use of ChCl-BuIM improved both the selectivity and affinity of the MIP adsorbent towards naproxen.
Competitive recognition studies of the Fe3O4@MIP-ChCl-BuIM using naproxen and structurally similar
non-steroidal anti-inflammatory drugs revealed that the Fe3O4@MIP-ChCl-BuIM had high selectivity for naproxen. A cytotoxicity test showed that the synthesised ChCl-BuIM was non-toxic, as the human normal cell
lines MCF-10A, and BEAS-2B maintained viability above 50%. These results show that Fe3O4@MIP-ChCl-BuIM
has potential for use as a functional adsorption material for the removal of naproxen from water samples. |
| first_indexed | 2025-11-15T19:52:50Z |
| format | Article |
| id | uthm-1037 |
| institution | Universiti Tun Hussein Onn Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T19:52:50Z |
| publishDate | 2021 |
| publisher | Elsevier |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | uthm-10372021-08-22T08:17:39Z http://eprints.uthm.edu.my/1037/ Application of a new choline-imidazole based deep eutectic solvents in hybrid magnetic molecularly imprinted polymer for efficient and selective removal of naproxen from aqueous samples Husin, Nor Aniisah Muhamad, Musthahimah Yahaya, Noorfatimah Miskam, Mazidatulakmam Nik Mohamed Kamal, Nik Nur Syazni Asman, Saliza Raoov, Muggundha Mohamad Zain, Nur Nadhirah T Technology (General) A magnetic molecularly imprinted polymer (Fe3O4@MIP) with naproxen (as template) was successfully prepared by adding a co-solvent consisting of a choline-imidazole based deep eutectic solvent (ChCl-BuIM) during polymerisation. The morphological, functional group, and magnetic characteristics of the synthesised materials were characterised by elemental analysis, Fourier transform-infrared spectroscopy, scanning electron microscopy, and vibrating sample magnetometer. This hybrid Fe3O4@MIP-ChCl-BuIM material was used as a magnetic adsorbent for efficient and selective removal of naproxen from wastewater samples. A batch adsorption study showed that adsorption of naproxen onto the multilayer surface of the adsorbent through a chemisorption mechanism. The data showed that the adsorption was feasible, spontaneous, and exothermic. The Fe3O4@MIP-ChCl-BuIM removed more naproxen (93.2–97.1%) than Fe3O4@MIP without ChCl-BuIM (83.2–88.9%). This finding confirms that the use of ChCl-BuIM improved both the selectivity and affinity of the MIP adsorbent towards naproxen. Competitive recognition studies of the Fe3O4@MIP-ChCl-BuIM using naproxen and structurally similar non-steroidal anti-inflammatory drugs revealed that the Fe3O4@MIP-ChCl-BuIM had high selectivity for naproxen. A cytotoxicity test showed that the synthesised ChCl-BuIM was non-toxic, as the human normal cell lines MCF-10A, and BEAS-2B maintained viability above 50%. These results show that Fe3O4@MIP-ChCl-BuIM has potential for use as a functional adsorption material for the removal of naproxen from water samples. Elsevier 2021 Article PeerReviewed text en http://eprints.uthm.edu.my/1037/1/J11948_bef6a747948caa54502eec437e9dd1b2.pdf Husin, Nor Aniisah and Muhamad, Musthahimah and Yahaya, Noorfatimah and Miskam, Mazidatulakmam and Nik Mohamed Kamal, Nik Nur Syazni and Asman, Saliza and Raoov, Muggundha and Mohamad Zain, Nur Nadhirah (2021) Application of a new choline-imidazole based deep eutectic solvents in hybrid magnetic molecularly imprinted polymer for efficient and selective removal of naproxen from aqueous samples. Materials Chemistry and Physics, 261. pp. 1-15. ISSN 0254-0584 https://doi.org/10.1016/j.matchemphys.2021.124228 |
| spellingShingle | T Technology (General) Husin, Nor Aniisah Muhamad, Musthahimah Yahaya, Noorfatimah Miskam, Mazidatulakmam Nik Mohamed Kamal, Nik Nur Syazni Asman, Saliza Raoov, Muggundha Mohamad Zain, Nur Nadhirah Application of a new choline-imidazole based deep eutectic solvents in hybrid magnetic molecularly imprinted polymer for efficient and selective removal of naproxen from aqueous samples |
| title | Application of a new choline-imidazole based deep eutectic solvents in
hybrid magnetic molecularly imprinted polymer for efficient and selective
removal of naproxen from aqueous samples |
| title_full | Application of a new choline-imidazole based deep eutectic solvents in
hybrid magnetic molecularly imprinted polymer for efficient and selective
removal of naproxen from aqueous samples |
| title_fullStr | Application of a new choline-imidazole based deep eutectic solvents in
hybrid magnetic molecularly imprinted polymer for efficient and selective
removal of naproxen from aqueous samples |
| title_full_unstemmed | Application of a new choline-imidazole based deep eutectic solvents in
hybrid magnetic molecularly imprinted polymer for efficient and selective
removal of naproxen from aqueous samples |
| title_short | Application of a new choline-imidazole based deep eutectic solvents in
hybrid magnetic molecularly imprinted polymer for efficient and selective
removal of naproxen from aqueous samples |
| title_sort | application of a new choline-imidazole based deep eutectic solvents in
hybrid magnetic molecularly imprinted polymer for efficient and selective
removal of naproxen from aqueous samples |
| topic | T Technology (General) |
| url | http://eprints.uthm.edu.my/1037/ http://eprints.uthm.edu.my/1037/ http://eprints.uthm.edu.my/1037/1/J11948_bef6a747948caa54502eec437e9dd1b2.pdf |