Toxicity of zinc oxide nanoparticles on human skin dermal cells

Zinc oxide (ZnO) has special physical and chemical characteristics which enable it to be utilized in numerous applications including electronics, sunscreens, pigments, and most notably in biomedical applications. Nanoemulsions containing zinc oxide nanoparticles (ZnO NPs) are progressively sought-af...

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Main Authors: Maheswaran, H., Wong, L.S., Dhanapal, A.C.T.A., Narendhirakannan, R.T., Janakiraman, A.K., Djearamane, S.
Format: UTAR Academic Staff Publication
Published: Journal of Experimental Biology and Agricultural Sciences (JEBAS) 2021
Subjects:
Online Access:https://www.jebas.org/abstract.php?article_id=498
http://eprints.utar.edu.my/4194/1/TOXICITY_OF_ZINC_OXIDE_NANOPARTICLES_ON_HUMAN_SKIN_DERMAL_CELLS.pdf
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author Maheswaran, H.
Wong, L.S.
Dhanapal, A.C.T.A.
Narendhirakannan, R.T.
Janakiraman, A.K.
Djearamane, S.
author_facet Maheswaran, H.
Wong, L.S.
Dhanapal, A.C.T.A.
Narendhirakannan, R.T.
Janakiraman, A.K.
Djearamane, S.
author_sort Maheswaran, H.
building UTAR Institutional Repository
collection Online Access
description Zinc oxide (ZnO) has special physical and chemical characteristics which enable it to be utilized in numerous applications including electronics, sunscreens, pigments, and most notably in biomedical applications. Nanoemulsions containing zinc oxide nanoparticles (ZnO NPs) are progressively sought-after as an active component in cosmetic formulations and are used in sunscreens, moisturizers, and antiaging products. Zinc paste bandages including Unna boot consist of open wove cotton gauze treated with ZnO paste are now common medicaments for leg ulcers. The damaged and broken skins are vulnerable to ZnO NPs uptake. This being the case, ZnO NPs on the skin surface can affect the functions of surrounding cells in numerous ways by penetrating into the skin cells. This could exert toxicity effects on the skin cells over time depending on the concentration and site of ZnO NPs exposure. This review brings together some findings regarding the toxicity of ZnO NPs on human skin dermal cells and thus in turn enlightens the safer usage of ZnO NPs in skin care applications.
first_indexed 2025-11-15T19:33:02Z
format UTAR Academic Staff Publication
id utar-4194
institution Universiti Tunku Abdul Rahman
institution_category Local University
last_indexed 2025-11-15T19:33:02Z
publishDate 2021
publisher Journal of Experimental Biology and Agricultural Sciences (JEBAS)
recordtype eprints
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spelling utar-41942021-07-09T08:31:37Z Toxicity of zinc oxide nanoparticles on human skin dermal cells Maheswaran, H. Wong, L.S. Dhanapal, A.C.T.A. Narendhirakannan, R.T. Janakiraman, A.K. Djearamane, S. HD Industries. Land use. Labor QH Natural history RA Public aspects of medicine RL Dermatology TP Chemical technology Zinc oxide (ZnO) has special physical and chemical characteristics which enable it to be utilized in numerous applications including electronics, sunscreens, pigments, and most notably in biomedical applications. Nanoemulsions containing zinc oxide nanoparticles (ZnO NPs) are progressively sought-after as an active component in cosmetic formulations and are used in sunscreens, moisturizers, and antiaging products. Zinc paste bandages including Unna boot consist of open wove cotton gauze treated with ZnO paste are now common medicaments for leg ulcers. The damaged and broken skins are vulnerable to ZnO NPs uptake. This being the case, ZnO NPs on the skin surface can affect the functions of surrounding cells in numerous ways by penetrating into the skin cells. This could exert toxicity effects on the skin cells over time depending on the concentration and site of ZnO NPs exposure. This review brings together some findings regarding the toxicity of ZnO NPs on human skin dermal cells and thus in turn enlightens the safer usage of ZnO NPs in skin care applications. Journal of Experimental Biology and Agricultural Sciences (JEBAS) 2021 UTAR Academic Staff Publication NonPeerReviewed application/pdf http://eprints.utar.edu.my/4194/1/TOXICITY_OF_ZINC_OXIDE_NANOPARTICLES_ON_HUMAN_SKIN_DERMAL_CELLS.pdf https://www.jebas.org/abstract.php?article_id=498 Maheswaran, H. and Wong, L.S. and Dhanapal, A.C.T.A. and Narendhirakannan, R.T. and Janakiraman, A.K. and Djearamane, S. (2021) Toxicity of zinc oxide nanoparticles on human skin dermal cells. Journal of Experimental Biology and Agricultural Sciences (JEBAS). http://eprints.utar.edu.my/4194/
spellingShingle HD Industries. Land use. Labor
QH Natural history
RA Public aspects of medicine
RL Dermatology
TP Chemical technology
Maheswaran, H.
Wong, L.S.
Dhanapal, A.C.T.A.
Narendhirakannan, R.T.
Janakiraman, A.K.
Djearamane, S.
Toxicity of zinc oxide nanoparticles on human skin dermal cells
title Toxicity of zinc oxide nanoparticles on human skin dermal cells
title_full Toxicity of zinc oxide nanoparticles on human skin dermal cells
title_fullStr Toxicity of zinc oxide nanoparticles on human skin dermal cells
title_full_unstemmed Toxicity of zinc oxide nanoparticles on human skin dermal cells
title_short Toxicity of zinc oxide nanoparticles on human skin dermal cells
title_sort toxicity of zinc oxide nanoparticles on human skin dermal cells
topic HD Industries. Land use. Labor
QH Natural history
RA Public aspects of medicine
RL Dermatology
TP Chemical technology
url https://www.jebas.org/abstract.php?article_id=498
https://www.jebas.org/abstract.php?article_id=498
http://eprints.utar.edu.my/4194/1/TOXICITY_OF_ZINC_OXIDE_NANOPARTICLES_ON_HUMAN_SKIN_DERMAL_CELLS.pdf