Cytotoxic effects of zinc oxide nanoparticles on Chlorella Vulgaris

Nanoparticles such as zinc oxide nanoparticles (ZnO NPs) have a wide range of applications in industrial and personal care products, but, at the same time, the presence of nanoparticles causes negative impact to aquatic ecosystem and the organisms within. In this study, the cytotoxic effect of ZnO N...

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Main Authors: Djearamane, S., Wong, L. S., Lim, Y. M., Lee, P. F.
Format: UTAR Academic Staff Publication
Published: EM International 2019
Subjects:
Online Access:http://eprints.utar.edu.my/4140/
http://eprints.utar.edu.my/4140/1/Cytotoxic_effects_of_zinc_oxide_nanoparticles_on_Chlorella_Vulgaris.pdf
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author Djearamane, S.
Wong, L. S.
Lim, Y. M.
Lee, P. F.
author_facet Djearamane, S.
Wong, L. S.
Lim, Y. M.
Lee, P. F.
author_sort Djearamane, S.
building UTAR Institutional Repository
collection Online Access
description Nanoparticles such as zinc oxide nanoparticles (ZnO NPs) have a wide range of applications in industrial and personal care products, but, at the same time, the presence of nanoparticles causes negative impact to aquatic ecosystem and the organisms within. In this study, the cytotoxic effect of ZnO NPs on fresh water microalga Chlorella vulgaris is reported. C. vulgaris cells were treated with 10, 50, 100, 150 and 200 mg/L of ZnO NPs for 72 h. Cytotoxicity effects of ZnO NPs were assessed by measuring the fluorescence emission of chlorophyll using fluorescent spectrophotometer, algal biomass by spectrophotometer and cell viability through counting viable cells at 24, 48 and 72 h. Exposure to ZnO NPs caused a decrease in chlorophyll content, cell viability and algal biomass. The cytotoxic effects increased as the concentration and exposure duration of ZnO NPs increased. Toxicity of ZnO NPs was indicated by reduction in the chlorophyll content, cell viability and biomass. This study showed the potential of C. vulgaris to be a bioindicator for ZnO NPs' toxicity in aquatic environment.
first_indexed 2025-11-15T19:32:55Z
format UTAR Academic Staff Publication
id utar-4140
institution Universiti Tunku Abdul Rahman
institution_category Local University
last_indexed 2025-11-15T19:32:55Z
publishDate 2019
publisher EM International
recordtype eprints
repository_type Digital Repository
spelling utar-41402021-07-06T09:24:16Z Cytotoxic effects of zinc oxide nanoparticles on Chlorella Vulgaris Djearamane, S. Wong, L. S. Lim, Y. M. Lee, P. F. HD Industries. Land use. Labor QH Natural history QR Microbiology RM Therapeutics. Pharmacology SF Animal culture SH Aquaculture. Fisheries. Angling TP Chemical technology Nanoparticles such as zinc oxide nanoparticles (ZnO NPs) have a wide range of applications in industrial and personal care products, but, at the same time, the presence of nanoparticles causes negative impact to aquatic ecosystem and the organisms within. In this study, the cytotoxic effect of ZnO NPs on fresh water microalga Chlorella vulgaris is reported. C. vulgaris cells were treated with 10, 50, 100, 150 and 200 mg/L of ZnO NPs for 72 h. Cytotoxicity effects of ZnO NPs were assessed by measuring the fluorescence emission of chlorophyll using fluorescent spectrophotometer, algal biomass by spectrophotometer and cell viability through counting viable cells at 24, 48 and 72 h. Exposure to ZnO NPs caused a decrease in chlorophyll content, cell viability and algal biomass. The cytotoxic effects increased as the concentration and exposure duration of ZnO NPs increased. Toxicity of ZnO NPs was indicated by reduction in the chlorophyll content, cell viability and biomass. This study showed the potential of C. vulgaris to be a bioindicator for ZnO NPs' toxicity in aquatic environment. EM International 2019 UTAR Academic Staff Publication NonPeerReviewed application/pdf http://eprints.utar.edu.my/4140/1/Cytotoxic_effects_of_zinc_oxide_nanoparticles_on_Chlorella_Vulgaris.pdf Djearamane, S. and Wong, L. S. and Lim, Y. M. and Lee, P. F. (2019) Cytotoxic effects of zinc oxide nanoparticles on Chlorella Vulgaris. EM International. http://eprints.utar.edu.my/4140/
spellingShingle HD Industries. Land use. Labor
QH Natural history
QR Microbiology
RM Therapeutics. Pharmacology
SF Animal culture
SH Aquaculture. Fisheries. Angling
TP Chemical technology
Djearamane, S.
Wong, L. S.
Lim, Y. M.
Lee, P. F.
Cytotoxic effects of zinc oxide nanoparticles on Chlorella Vulgaris
title Cytotoxic effects of zinc oxide nanoparticles on Chlorella Vulgaris
title_full Cytotoxic effects of zinc oxide nanoparticles on Chlorella Vulgaris
title_fullStr Cytotoxic effects of zinc oxide nanoparticles on Chlorella Vulgaris
title_full_unstemmed Cytotoxic effects of zinc oxide nanoparticles on Chlorella Vulgaris
title_short Cytotoxic effects of zinc oxide nanoparticles on Chlorella Vulgaris
title_sort cytotoxic effects of zinc oxide nanoparticles on chlorella vulgaris
topic HD Industries. Land use. Labor
QH Natural history
QR Microbiology
RM Therapeutics. Pharmacology
SF Animal culture
SH Aquaculture. Fisheries. Angling
TP Chemical technology
url http://eprints.utar.edu.my/4140/
http://eprints.utar.edu.my/4140/1/Cytotoxic_effects_of_zinc_oxide_nanoparticles_on_Chlorella_Vulgaris.pdf