Synthesis and characterization of 1,3,4-oxadiazoles bearing an indole ring
1,3,4-oxadiazoles are important in various fields and have been involved in many studies by researchers. 1,3,4-oxadiazoles have many biological activities, for example, antifungal, antibacterial and anti-oxidant activities. A carboxylic acid hydrazide was synthesized from the reaction between an ind...
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| Format: | Final Year Project / Dissertation / Thesis |
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2020
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| Online Access: | http://eprints.utar.edu.my/4033/ http://eprints.utar.edu.my/4033/1/FYP_correction_Yu_Xuan_final.pdf |
| _version_ | 1848886057593995264 |
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| author | Ng, Yu Xuan |
| author_facet | Ng, Yu Xuan |
| author_sort | Ng, Yu Xuan |
| building | UTAR Institutional Repository |
| collection | Online Access |
| description | 1,3,4-oxadiazoles are important in various fields and have been involved in many studies by researchers. 1,3,4-oxadiazoles have many biological activities, for example, antifungal, antibacterial and anti-oxidant activities. A carboxylic acid hydrazide was synthesized from the reaction between an indole ester and a hydrazine hydrate and used as a starting material of 1,3,4-oxadiazole derivatives. There were four 1,3,4-oxadiazoles being synthesized in this project. The 1,3,4-oxadiazole derivatives were synthesized from carboxylic acid hydrazide reacted with different benzoic acid derivatives with the presence of POCl3. The percentage yields for the synthesized 1,3,4-oxadizoles were between 8% to 70%. For the characterization of the carboxylic acid hydrazide and the 1,3,4-oxadiazoles were using various instruments such as melting point apparatus, FT-IR, 1H NMR,13C NMR , DEPT, HMQC, and HMBC. |
| first_indexed | 2025-11-15T19:32:27Z |
| format | Final Year Project / Dissertation / Thesis |
| id | utar-4033 |
| institution | Universiti Tunku Abdul Rahman |
| institution_category | Local University |
| last_indexed | 2025-11-15T19:32:27Z |
| publishDate | 2020 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | utar-40332021-05-06T12:34:34Z Synthesis and characterization of 1,3,4-oxadiazoles bearing an indole ring Ng, Yu Xuan QD Chemistry 1,3,4-oxadiazoles are important in various fields and have been involved in many studies by researchers. 1,3,4-oxadiazoles have many biological activities, for example, antifungal, antibacterial and anti-oxidant activities. A carboxylic acid hydrazide was synthesized from the reaction between an indole ester and a hydrazine hydrate and used as a starting material of 1,3,4-oxadiazole derivatives. There were four 1,3,4-oxadiazoles being synthesized in this project. The 1,3,4-oxadiazole derivatives were synthesized from carboxylic acid hydrazide reacted with different benzoic acid derivatives with the presence of POCl3. The percentage yields for the synthesized 1,3,4-oxadizoles were between 8% to 70%. For the characterization of the carboxylic acid hydrazide and the 1,3,4-oxadiazoles were using various instruments such as melting point apparatus, FT-IR, 1H NMR,13C NMR , DEPT, HMQC, and HMBC. 2020-10-08 Final Year Project / Dissertation / Thesis NonPeerReviewed application/pdf http://eprints.utar.edu.my/4033/1/FYP_correction_Yu_Xuan_final.pdf Ng, Yu Xuan (2020) Synthesis and characterization of 1,3,4-oxadiazoles bearing an indole ring. Final Year Project, UTAR. http://eprints.utar.edu.my/4033/ |
| spellingShingle | QD Chemistry Ng, Yu Xuan Synthesis and characterization of 1,3,4-oxadiazoles bearing an indole ring |
| title | Synthesis and characterization of 1,3,4-oxadiazoles bearing an indole ring |
| title_full | Synthesis and characterization of 1,3,4-oxadiazoles bearing an indole ring |
| title_fullStr | Synthesis and characterization of 1,3,4-oxadiazoles bearing an indole ring |
| title_full_unstemmed | Synthesis and characterization of 1,3,4-oxadiazoles bearing an indole ring |
| title_short | Synthesis and characterization of 1,3,4-oxadiazoles bearing an indole ring |
| title_sort | synthesis and characterization of 1,3,4-oxadiazoles bearing an indole ring |
| topic | QD Chemistry |
| url | http://eprints.utar.edu.my/4033/ http://eprints.utar.edu.my/4033/1/FYP_correction_Yu_Xuan_final.pdf |