Childhood systemic lupus erythematosus (CSLE) and its psychological impact: dual tertiary centre experience
Introduction: This study investigated the potential psychological problems in children with systemic lupus erythematosus (SLE) compared to healthy children. Methods: A non-probability sample study was performed on children with SLE, and their peers aged 6 to 18 years. The Child Behaviour Checklist...
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| Format: | Thesis |
| Language: | English |
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2023
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| Online Access: | http://eprints.usm.my/62503/ http://eprints.usm.my/62503/1/Mushamma%20Mursheeda%20Amiruddin-E.pdf |
| _version_ | 1848885004656967680 |
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| author | Amiruddin, Mushamma Mursheeda |
| author_facet | Amiruddin, Mushamma Mursheeda |
| author_sort | Amiruddin, Mushamma Mursheeda |
| building | USM Institutional Repository |
| collection | Online Access |
| description | Introduction: This study investigated the potential psychological problems in children with systemic lupus erythematosus (SLE) compared to healthy children.
Methods: A non-probability sample study was performed on children with SLE, and their peers aged 6 to 18 years. The Child Behaviour Checklist for Ages 6–18 (CBCL 6–18) was completed by the participant's parents. The questionnaire helps to assess the children's emotional and psychological issues. In addition, their demographic and clinical information was also gathered. The analysis of CBCL scores was performed using independent t-tests.
Results: A total of 111 children were recruited, 41 of whom had SLE. Most of the SLE participants were Malay females aged 13–15 who are attending secondary school. Most of them are from low socioeconomic status. The findings revealed that the children with SLE scored substantially higher than the healthy children (the control group) on three CBCL subscales. The subscales mentioned are internalising subscale [mean difference of 3.13, 95% confidence interval (CI) [0.30, 5.95] and P = 0.03], withdrawn subscale [mean
difference of 1.50, 95% CI [0.42, 2.60] and P = 0.01], and attention problem [mean
difference of 2.14, 95% CI [0.35, 3.94] and P = 0.02]. Besides that, SLE participants' scores on other subscales, including anxiety and somatic, were also considerably higher than the control group, although these differences were not statistically significant.
Conclusion: Children with SLE are perceived to have greater psychological problems compared to their healthy peers. They were more socially withdrawn and inattentive, as indicated by the CBCL scores. |
| first_indexed | 2025-11-15T19:15:42Z |
| format | Thesis |
| id | usm-62503 |
| institution | Universiti Sains Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T19:15:42Z |
| publishDate | 2023 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | usm-625032025-06-24T08:07:44Z http://eprints.usm.my/62503/ Childhood systemic lupus erythematosus (CSLE) and its psychological impact: dual tertiary centre experience Amiruddin, Mushamma Mursheeda R Medicine RA440-440.87 Study and teaching. Research RC Internal medicine Introduction: This study investigated the potential psychological problems in children with systemic lupus erythematosus (SLE) compared to healthy children. Methods: A non-probability sample study was performed on children with SLE, and their peers aged 6 to 18 years. The Child Behaviour Checklist for Ages 6–18 (CBCL 6–18) was completed by the participant's parents. The questionnaire helps to assess the children's emotional and psychological issues. In addition, their demographic and clinical information was also gathered. The analysis of CBCL scores was performed using independent t-tests. Results: A total of 111 children were recruited, 41 of whom had SLE. Most of the SLE participants were Malay females aged 13–15 who are attending secondary school. Most of them are from low socioeconomic status. The findings revealed that the children with SLE scored substantially higher than the healthy children (the control group) on three CBCL subscales. The subscales mentioned are internalising subscale [mean difference of 3.13, 95% confidence interval (CI) [0.30, 5.95] and P = 0.03], withdrawn subscale [mean difference of 1.50, 95% CI [0.42, 2.60] and P = 0.01], and attention problem [mean difference of 2.14, 95% CI [0.35, 3.94] and P = 0.02]. Besides that, SLE participants' scores on other subscales, including anxiety and somatic, were also considerably higher than the control group, although these differences were not statistically significant. Conclusion: Children with SLE are perceived to have greater psychological problems compared to their healthy peers. They were more socially withdrawn and inattentive, as indicated by the CBCL scores. 2023 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/62503/1/Mushamma%20Mursheeda%20Amiruddin-E.pdf Amiruddin, Mushamma Mursheeda (2023) Childhood systemic lupus erythematosus (CSLE) and its psychological impact: dual tertiary centre experience. Masters thesis, Universiti Sains Malaysia. |
| spellingShingle | R Medicine RA440-440.87 Study and teaching. Research RC Internal medicine Amiruddin, Mushamma Mursheeda Childhood systemic lupus erythematosus (CSLE) and its psychological impact: dual tertiary centre experience |
| title | Childhood systemic lupus erythematosus (CSLE) and its psychological impact: dual tertiary centre experience |
| title_full | Childhood systemic lupus erythematosus (CSLE) and its psychological impact: dual tertiary centre experience |
| title_fullStr | Childhood systemic lupus erythematosus (CSLE) and its psychological impact: dual tertiary centre experience |
| title_full_unstemmed | Childhood systemic lupus erythematosus (CSLE) and its psychological impact: dual tertiary centre experience |
| title_short | Childhood systemic lupus erythematosus (CSLE) and its psychological impact: dual tertiary centre experience |
| title_sort | childhood systemic lupus erythematosus (csle) and its psychological impact: dual tertiary centre experience |
| topic | R Medicine RA440-440.87 Study and teaching. Research RC Internal medicine |
| url | http://eprints.usm.my/62503/ http://eprints.usm.my/62503/1/Mushamma%20Mursheeda%20Amiruddin-E.pdf |