Exposure to endotoxin level in inhalable rice dust among rice mill workers
Endotoxins are the lipid portions of lipopolysaccharides (LPSs) which is a part of the outer membrane of the cell wall of gram-negative bacteria. Rice dust containing endotoxin can cause systemic inflammatory response syndrome (SIRS) and multiple organ dysfunction syndromes (MODS). The aim and ob...
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| Format: | Monograph |
| Language: | English |
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Universiti Sains Malaysia
2016
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| Online Access: | http://eprints.usm.my/62387/ http://eprints.usm.my/62387/1/ROS%20AIDA%20BINTI%20MOHD%20ZIN%20-%20e.pdf |
| _version_ | 1848884969978462208 |
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| author | Zin, Ros Aida Mohd |
| author_facet | Zin, Ros Aida Mohd |
| author_sort | Zin, Ros Aida Mohd |
| building | USM Institutional Repository |
| collection | Online Access |
| description | Endotoxins are the lipid portions of lipopolysaccharides (LPSs) which is a part of
the outer membrane of the cell wall of gram-negative bacteria. Rice dust containing
endotoxin can cause systemic inflammatory response syndrome (SIRS) and multiple organ
dysfunction syndromes (MODS). The aim and objective of this study are to compare the
concentration of dust, endotoxin exposure level and lung function between rice mill
workers and management workers in Kelantan. Samples were collected using Institute of
Occupational Medicine (IOM) inhalable dust sampler loaded with glass fiber filter (GFA)
for 8 hours and analysed by using Limulus amebocyte lysate (LAL) test. The lung functions
were tested by using the spirometer to measure the amount of maximal air breathed out
over pre-exposure (before work) and post-exposure (after work). Results showed that the
dust concentration (mg/m3) of rice mill workers (median: 8.86, range: 2.68-15.93) was
significantly different compared with the LJSM management workers (median: 1.47, range:
0.22-2.53) and the rice mill management workers (median: 0.70, range: 0.47-1.72) p=0.005.
The endotoxin concentration (EU/ml) of the rice mill workers (median: 0.14, range: 0.11-
0.16) was significantly different compared with the rice mill management workers (median:
0.06, range: 0.03-0.10) and the USM management workers (median: 0.05, range: 0.04-
0.09). The forced vital capacity (FVC), forced expiratory volume in one second (FEV1) and
FEV1/FVC% among the three groups shows no different between pre and post-exposure at
(p-0.601, p-0.960 and p=0.660), respectively. This study is important to promote health awareness among workers involving knowledge, attitude and safety practices about personal protective equipment (PPE) and gives benefit for other researchers for further investigations about rice dust in Malaysia. |
| first_indexed | 2025-11-15T19:15:09Z |
| format | Monograph |
| id | usm-62387 |
| institution | Universiti Sains Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T19:15:09Z |
| publishDate | 2016 |
| publisher | Universiti Sains Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | usm-623872025-07-21T03:28:37Z http://eprints.usm.my/62387/ Exposure to endotoxin level in inhalable rice dust among rice mill workers Zin, Ros Aida Mohd R Medicine (General) R735-854 Medical education. Medical schools. Research Endotoxins are the lipid portions of lipopolysaccharides (LPSs) which is a part of the outer membrane of the cell wall of gram-negative bacteria. Rice dust containing endotoxin can cause systemic inflammatory response syndrome (SIRS) and multiple organ dysfunction syndromes (MODS). The aim and objective of this study are to compare the concentration of dust, endotoxin exposure level and lung function between rice mill workers and management workers in Kelantan. Samples were collected using Institute of Occupational Medicine (IOM) inhalable dust sampler loaded with glass fiber filter (GFA) for 8 hours and analysed by using Limulus amebocyte lysate (LAL) test. The lung functions were tested by using the spirometer to measure the amount of maximal air breathed out over pre-exposure (before work) and post-exposure (after work). Results showed that the dust concentration (mg/m3) of rice mill workers (median: 8.86, range: 2.68-15.93) was significantly different compared with the LJSM management workers (median: 1.47, range: 0.22-2.53) and the rice mill management workers (median: 0.70, range: 0.47-1.72) p=0.005. The endotoxin concentration (EU/ml) of the rice mill workers (median: 0.14, range: 0.11- 0.16) was significantly different compared with the rice mill management workers (median: 0.06, range: 0.03-0.10) and the USM management workers (median: 0.05, range: 0.04- 0.09). The forced vital capacity (FVC), forced expiratory volume in one second (FEV1) and FEV1/FVC% among the three groups shows no different between pre and post-exposure at (p-0.601, p-0.960 and p=0.660), respectively. This study is important to promote health awareness among workers involving knowledge, attitude and safety practices about personal protective equipment (PPE) and gives benefit for other researchers for further investigations about rice dust in Malaysia. Universiti Sains Malaysia 2016 Monograph NonPeerReviewed application/pdf en http://eprints.usm.my/62387/1/ROS%20AIDA%20BINTI%20MOHD%20ZIN%20-%20e.pdf Zin, Ros Aida Mohd (2016) Exposure to endotoxin level in inhalable rice dust among rice mill workers. Project Report. Universiti Sains Malaysia. (Submitted) |
| spellingShingle | R Medicine (General) R735-854 Medical education. Medical schools. Research Zin, Ros Aida Mohd Exposure to endotoxin level in inhalable rice dust among rice mill workers |
| title | Exposure to endotoxin level in inhalable rice dust
among rice mill workers |
| title_full | Exposure to endotoxin level in inhalable rice dust
among rice mill workers |
| title_fullStr | Exposure to endotoxin level in inhalable rice dust
among rice mill workers |
| title_full_unstemmed | Exposure to endotoxin level in inhalable rice dust
among rice mill workers |
| title_short | Exposure to endotoxin level in inhalable rice dust
among rice mill workers |
| title_sort | exposure to endotoxin level in inhalable rice dust
among rice mill workers |
| topic | R Medicine (General) R735-854 Medical education. Medical schools. Research |
| url | http://eprints.usm.my/62387/ http://eprints.usm.my/62387/1/ROS%20AIDA%20BINTI%20MOHD%20ZIN%20-%20e.pdf |