Prevalence and risk factors for dyslipidemia and hypertension in diabetes mellitus among the paediatric population in Hospital Universiti Sains Malaysia (USM), Kelantan, Malaysia
Objective: This study aims to evaluate the prevalence and risk factors for dyslipidaemia and hypertension in diabetes mellitus among the pediatric population in Hospital Universiti Sains Malaysia (USM), Kelantan, Malaysia Method: A retrospective cross-sectional study was conducted at Hospital Uni...
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| Format: | Thesis |
| Language: | English |
| Published: |
2023
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| Online Access: | http://eprints.usm.my/62339/ http://eprints.usm.my/62339/1/Mohamad%20Qazreen%20Ahmad%20Shawaludin-E.pdf |
| _version_ | 1848884955626602496 |
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| author | Shawaludin, Mohamad Qazreen Ahmad |
| author_facet | Shawaludin, Mohamad Qazreen Ahmad |
| author_sort | Shawaludin, Mohamad Qazreen Ahmad |
| building | USM Institutional Repository |
| collection | Online Access |
| description | Objective:
This study aims to evaluate the prevalence and risk factors for dyslipidaemia and hypertension in diabetes mellitus among the pediatric population in Hospital Universiti Sains Malaysia (USM), Kelantan, Malaysia
Method:
A retrospective cross-sectional study was conducted at Hospital Universiti Sains Malaysia (USM), Kelantan, Malaysia. A total of 132 patients diagnosed with diabetes mellitus for at least six months, aged below 18 years old, were recruited for this study. Demographic data (age, race, parent’s monthly income, family history of cardiovascular disease, height, weight, body mass index (BMI), and blood pressure), diabetes profile (type and duration diabetes, age of diagnosis, SMBG monitoring, and type of treatment) and laboratory values (HbA1c, lipid profile) were obtained from patient’s medical records. Multiple logistic regression models were used to examine the associations between risk variables with dyslipidemia and hypertension in diabetes mellitus children.
Result:
A total of 132 patients were studied, 53.8% female, with a median age of 16.0 (13.0 – 17.0) years and an age of diagnosis of 10.0 (8.0 -12.0) years. We found that the prevalence of dyslipidemia and hypertension was 62.1% and 19.7%, respectively. Multiple logistic regression analysis showed systolic blood pressure (mmHg) (adjusted OR, 95% CI) 1.07 (1.02, 1.12), diabetes duration (years) 1.76 (1.37, 2.25), and HbA1c value 1.35 (1.06, 1.72) were the significant prognostic factors for dyslipidaemia. Meanwhile, weight (kg) 1.16 (1.07,1.25), duration of diabetes (years) 1.49 (1.14, 1.96), HbA1c (%) 1.56 (1.12, 2.15) and LDL value (mmol/L) 2.98 are significant factors for hypertension.
Conclusion:
The prevalence rates of dyslipidaemia and hypertension in pediatric diabetes mellitus referred to our center were 62.1% and 19.7%, respectively. The most significant prognostic factors for dyslipidaemia and hypertension were the duration of diabetes and glycaemic control (HbA1c). |
| first_indexed | 2025-11-15T19:14:56Z |
| format | Thesis |
| id | usm-62339 |
| institution | Universiti Sains Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T19:14:56Z |
| publishDate | 2023 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | usm-623392025-06-01T07:23:54Z http://eprints.usm.my/62339/ Prevalence and risk factors for dyslipidemia and hypertension in diabetes mellitus among the paediatric population in Hospital Universiti Sains Malaysia (USM), Kelantan, Malaysia Shawaludin, Mohamad Qazreen Ahmad R Medicine RA440-440.87 Study and teaching. Research RC31-1245 Internal medicine Objective: This study aims to evaluate the prevalence and risk factors for dyslipidaemia and hypertension in diabetes mellitus among the pediatric population in Hospital Universiti Sains Malaysia (USM), Kelantan, Malaysia Method: A retrospective cross-sectional study was conducted at Hospital Universiti Sains Malaysia (USM), Kelantan, Malaysia. A total of 132 patients diagnosed with diabetes mellitus for at least six months, aged below 18 years old, were recruited for this study. Demographic data (age, race, parent’s monthly income, family history of cardiovascular disease, height, weight, body mass index (BMI), and blood pressure), diabetes profile (type and duration diabetes, age of diagnosis, SMBG monitoring, and type of treatment) and laboratory values (HbA1c, lipid profile) were obtained from patient’s medical records. Multiple logistic regression models were used to examine the associations between risk variables with dyslipidemia and hypertension in diabetes mellitus children. Result: A total of 132 patients were studied, 53.8% female, with a median age of 16.0 (13.0 – 17.0) years and an age of diagnosis of 10.0 (8.0 -12.0) years. We found that the prevalence of dyslipidemia and hypertension was 62.1% and 19.7%, respectively. Multiple logistic regression analysis showed systolic blood pressure (mmHg) (adjusted OR, 95% CI) 1.07 (1.02, 1.12), diabetes duration (years) 1.76 (1.37, 2.25), and HbA1c value 1.35 (1.06, 1.72) were the significant prognostic factors for dyslipidaemia. Meanwhile, weight (kg) 1.16 (1.07,1.25), duration of diabetes (years) 1.49 (1.14, 1.96), HbA1c (%) 1.56 (1.12, 2.15) and LDL value (mmol/L) 2.98 are significant factors for hypertension. Conclusion: The prevalence rates of dyslipidaemia and hypertension in pediatric diabetes mellitus referred to our center were 62.1% and 19.7%, respectively. The most significant prognostic factors for dyslipidaemia and hypertension were the duration of diabetes and glycaemic control (HbA1c). 2023 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/62339/1/Mohamad%20Qazreen%20Ahmad%20Shawaludin-E.pdf Shawaludin, Mohamad Qazreen Ahmad (2023) Prevalence and risk factors for dyslipidemia and hypertension in diabetes mellitus among the paediatric population in Hospital Universiti Sains Malaysia (USM), Kelantan, Malaysia. Masters thesis, Universiti Sains Malaysia. |
| spellingShingle | R Medicine RA440-440.87 Study and teaching. Research RC31-1245 Internal medicine Shawaludin, Mohamad Qazreen Ahmad Prevalence and risk factors for dyslipidemia and hypertension in diabetes mellitus among the paediatric population in Hospital Universiti Sains Malaysia (USM), Kelantan, Malaysia |
| title | Prevalence and risk factors for dyslipidemia and hypertension in diabetes mellitus among the paediatric population in Hospital Universiti Sains Malaysia (USM), Kelantan, Malaysia |
| title_full | Prevalence and risk factors for dyslipidemia and hypertension in diabetes mellitus among the paediatric population in Hospital Universiti Sains Malaysia (USM), Kelantan, Malaysia |
| title_fullStr | Prevalence and risk factors for dyslipidemia and hypertension in diabetes mellitus among the paediatric population in Hospital Universiti Sains Malaysia (USM), Kelantan, Malaysia |
| title_full_unstemmed | Prevalence and risk factors for dyslipidemia and hypertension in diabetes mellitus among the paediatric population in Hospital Universiti Sains Malaysia (USM), Kelantan, Malaysia |
| title_short | Prevalence and risk factors for dyslipidemia and hypertension in diabetes mellitus among the paediatric population in Hospital Universiti Sains Malaysia (USM), Kelantan, Malaysia |
| title_sort | prevalence and risk factors for dyslipidemia and hypertension in diabetes mellitus among the paediatric population in hospital universiti sains malaysia (usm), kelantan, malaysia |
| topic | R Medicine RA440-440.87 Study and teaching. Research RC31-1245 Internal medicine |
| url | http://eprints.usm.my/62339/ http://eprints.usm.my/62339/1/Mohamad%20Qazreen%20Ahmad%20Shawaludin-E.pdf |