The impact of varying tract turning angle on fibre tractography reconstruction and diffusion tensor imaging indices
Impact of varying turning angle in fibre tractography reconstruction was evaluated. Diffusion tensor images were obtained retrospectively from Nordiclce (version 2.3.9, Nordic Neuro Lab) database available in AMDI-USM. All data were acquired using GE 1.5 Tesla MRI system (Signa HDxt, GE Healthcar...
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| Format: | Monograph |
| Language: | English |
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Universiti Sains Malaysia
2016
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| Online Access: | http://eprints.usm.my/62313/ http://eprints.usm.my/62313/1/NUR%27AIN%20NURJANNAH%20BINTI%20TOKEMIN%20-%20e.pdf |
| _version_ | 1848884948626309120 |
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| author | Tokemin, Nur’ain Nurjannah |
| author_facet | Tokemin, Nur’ain Nurjannah |
| author_sort | Tokemin, Nur’ain Nurjannah |
| building | USM Institutional Repository |
| collection | Online Access |
| description | Impact of varying turning angle in fibre tractography reconstruction was evaluated. Diffusion
tensor images were obtained retrospectively from Nordiclce (version 2.3.9, Nordic Neuro Lab)
database available in AMDI-USM. All data were acquired using GE 1.5 Tesla MRI system
(Signa HDxt, GE Healthcare). A healthy female subject with no associated neurological or brain
illness participated in the study. DTI post processing was performed in which DTI parametric
maps and fibre tractography were reconstructed. During fibre tracking, tract turning angle was
varied for 25°, 35°, 45° (default turning angle set by software developer), 55° and 65°. Then, the
assessment was performed on DTI indices including fractional anisotropy (FA), mean diffusivity
(MD) as well as number of fibres reconstructed. The values obtained for each angle were
compared with that of obtained using default angle. Tractographies of coipus callosum (CC) and
corticospinal tract (CST) were initiated by placement of single seed region of interest (ROI) on
CC, cerebral peduncle and centrum semiovale at superior part of brain. Results obtained showed
modification of turning angle from its default value has less impact on CC. There were no
differences in FA noted between the default angle with angle 35°, 55° and 65°. Besides, MD
showed decreases in percentage difference as the turning angle became large. Similar to number
of fibres which exhibited decrease in percentage from 8.4% at smallest angle to 3% at the largest
angle. However, the differences were not too significant. While for CST, small differences were
noted at 35° and 55°. Whereas larger percentage difference was found at 25° with 5.4%, 1.44%
and 30.3% for FA, MD and number of fibres respectively. Followed by 65° with 1.62%, 0.19%
and 16.2% for FA, MD and number fibres respectively. In conclusion, the modifications of tract turning angle do give impact on reconstruction of CST fibre bundle while lesser impact was seen on CC fibre bundles. |
| first_indexed | 2025-11-15T19:14:49Z |
| format | Monograph |
| id | usm-62313 |
| institution | Universiti Sains Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T19:14:49Z |
| publishDate | 2016 |
| publisher | Universiti Sains Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | usm-623132025-07-21T03:42:49Z http://eprints.usm.my/62313/ The impact of varying tract turning angle on fibre tractography reconstruction and diffusion tensor imaging indices Tokemin, Nur’ain Nurjannah R Medicine (General) RC Internal medicine Impact of varying turning angle in fibre tractography reconstruction was evaluated. Diffusion tensor images were obtained retrospectively from Nordiclce (version 2.3.9, Nordic Neuro Lab) database available in AMDI-USM. All data were acquired using GE 1.5 Tesla MRI system (Signa HDxt, GE Healthcare). A healthy female subject with no associated neurological or brain illness participated in the study. DTI post processing was performed in which DTI parametric maps and fibre tractography were reconstructed. During fibre tracking, tract turning angle was varied for 25°, 35°, 45° (default turning angle set by software developer), 55° and 65°. Then, the assessment was performed on DTI indices including fractional anisotropy (FA), mean diffusivity (MD) as well as number of fibres reconstructed. The values obtained for each angle were compared with that of obtained using default angle. Tractographies of coipus callosum (CC) and corticospinal tract (CST) were initiated by placement of single seed region of interest (ROI) on CC, cerebral peduncle and centrum semiovale at superior part of brain. Results obtained showed modification of turning angle from its default value has less impact on CC. There were no differences in FA noted between the default angle with angle 35°, 55° and 65°. Besides, MD showed decreases in percentage difference as the turning angle became large. Similar to number of fibres which exhibited decrease in percentage from 8.4% at smallest angle to 3% at the largest angle. However, the differences were not too significant. While for CST, small differences were noted at 35° and 55°. Whereas larger percentage difference was found at 25° with 5.4%, 1.44% and 30.3% for FA, MD and number of fibres respectively. Followed by 65° with 1.62%, 0.19% and 16.2% for FA, MD and number fibres respectively. In conclusion, the modifications of tract turning angle do give impact on reconstruction of CST fibre bundle while lesser impact was seen on CC fibre bundles. Universiti Sains Malaysia 2016 Monograph NonPeerReviewed application/pdf en http://eprints.usm.my/62313/1/NUR%27AIN%20NURJANNAH%20BINTI%20TOKEMIN%20-%20e.pdf Tokemin, Nur’ain Nurjannah (2016) The impact of varying tract turning angle on fibre tractography reconstruction and diffusion tensor imaging indices. Project Report. Universiti Sains Malaysia. (Submitted) |
| spellingShingle | R Medicine (General) RC Internal medicine Tokemin, Nur’ain Nurjannah The impact of varying tract turning angle on fibre tractography reconstruction and diffusion tensor imaging indices |
| title | The impact of varying tract turning angle on
fibre tractography reconstruction and
diffusion tensor imaging indices |
| title_full | The impact of varying tract turning angle on
fibre tractography reconstruction and
diffusion tensor imaging indices |
| title_fullStr | The impact of varying tract turning angle on
fibre tractography reconstruction and
diffusion tensor imaging indices |
| title_full_unstemmed | The impact of varying tract turning angle on
fibre tractography reconstruction and
diffusion tensor imaging indices |
| title_short | The impact of varying tract turning angle on
fibre tractography reconstruction and
diffusion tensor imaging indices |
| title_sort | impact of varying tract turning angle on
fibre tractography reconstruction and
diffusion tensor imaging indices |
| topic | R Medicine (General) RC Internal medicine |
| url | http://eprints.usm.my/62313/ http://eprints.usm.my/62313/1/NUR%27AIN%20NURJANNAH%20BINTI%20TOKEMIN%20-%20e.pdf |