In Silico Study And Synthesis Of Folic Acid-isoniazid Complex As A
Potential Antituberculosis Agent

QR Code

In Silico Study And Synthesis Of Folic Acid-isoniazid Complex As A Potential Antituberculosis Agent

This study aimed to design a novel conjugated compound, folic acid-isoniazid (FA-INH) conjugate, using ligand-based drug design and computational approaches, validated by molecular docking, and optimizing the key substrates for the conjugate synthesis through conventional and microwaved-assisted app...

Full description

Bibliographic Details
Main Author:	Tazizi, Mohammad Hafizie Dianel Mohd
Format:	Thesis
Language:	English
Published:	2024
Subjects:	RS1-441 Pharmacy and materia medica
Online Access:	http://eprints.usm.my/62240/ http://eprints.usm.my/62240/1/MOHAMMAD%20HAFIZIE%20DIANEL%20BIN%20MOHD%20TAZIZI%20-%20TESIS24.pdf

Similar Items

Derivatization And Conjugation Of Folic Acid To Improve Its Affinity Towards Folate Receptor Alpha On Cancerous Membrane Bilayer: An In Silico Insight
by: Althiabat, Mohammad Gasem Mohammad
Published: (2024)

Rational Drug Design Of New Folic Acid Analogues With High Binding Affinity And Anticancer Activity
by: Althiabat, Mohammad Gasem Mohammad
Published: (2020)

Studies On The Activity Of Isoniazid Derivatives And Their Combinations With Other Anti-TB Drugs On Mycobacterium Tuberculosis
by: Parumasivam, Thaigarajan
Published: (2012)

The Relationship Between The Blood Concentration Of Isoniazid, Rifampicin, Pyrazinamide And The Treatment Outcomes Of Pulmonary Tuberculosis Patients
by: Mahjoub, Abdallah Abdallah
Published: (2017)

Discovery Of New Targeting Agents Against Gapdh Receptor: In Silico And In Vitro Studies
by: Noh, Muhammad Amirul Asyraf
Published: (2023)

In Silico Prediction And In Vitro Evaluation Of Caffeic Acid And Its Derivatives As Potential Efflux Pump Inhibitor(S) In Pseudomonas Aeruginosa
by: Zakaria, Noor Zawani
Published: (2019)

Phenolic Acid Rich Fraction Of Gynura Procumbens As Potential Antihyperlipidemic And Antioxidant Agents
by: Murugesu, Kisantini
Published: (2018)

Synthesis and biological evaluation of aurones as potential neuroprotective agents: structure-activity and mode of action studies.
by: Lee , Chong Yew

An Alternative In Silico Method To Predict Passive Membrane Permeability Of Potential Spsb2-Inos Inhibitor
by: Choong, Fei Her
Published: (2024)

Aurones Of Amine And Carbamate Functionalities As Neuroprotective Agents With Multitargeting Potential: Synthesis, Structure-Activity Relationships And Mode Of Action Studies
by: Liew , Kok Fui
Published: (2016)

Phytochemical, Bioassay And In Silico Studies On Anti - Cholinesterase Activities Of Cassia Timoriensis Dc. And Cassia Grandis L.F.
by: Al-Hawarri, Maram Basem Tawfiq
Published: (2022)

In Vitro And In Silico Studies On Selected Malaysia Culinary Plants Against Dengue Ns2b-Ns3 Protease
by: Yong , Kai Sing
Published: (2016)

Rational Design And Synthesis Of Peptide Inhibitors Of Ns2b/Ns3 Protease As Therapeutic Agents For Dengue Virus Type 2
by: Abdalrazaq, Nadeem Abdalsatar
Published: (2021)

Evaluation On Polar Quassinoids Of Eurycoma Longifolia Jack As Potential Anti-benign Prostatic Hyperplasia Agents
by: Viji, Mathias Mathew Hipolith
Published: (2024)

Development And Characterisation Of Inhaled Andrographolide As An Anti-Cancer Agent
by: Aljothi, Shankar
Published: (2024)

Potential Of Stichopus horrens And Stichopus vastus Extracts As Anticancer And Wound Healing Agents: Effects On Breast Cancer And Fibroblast Cell Lines
by: Azemi, Nurul Adila
Published: (2014)

New strategy in development of cancer chemopreventive agent using Malaysia Plant
by: Seeni Mohamed , Md Azman PKM
Published: (2017)

Synthesis and characterization of orotic acid loaded chitosan inclusion complex
by: Hassani, Abdelkader, et al.
Published: (2020)

Customer Orientation, Social Values And Reward System On Performance Of Life Insurance Agents
by: Hon Tat, Muhahuam
Published: (1999)

Evaluation Of Antimicrobial Agents Prescribed By Universiti Sains Malaysia Panel Of Doctors: A Pharmacoepidemiology Approach
by: Ali Sawesi, Suhila
Published: (2003)

Synthesis, Characterisation And In Vitro Evaluation Of Disulphide Crosslinked Polymers As Potential Carriers For Colon Specific Drug Delivery System
by: Lau, Yong Khee
Published: (2015)

Structure Based Design And Synthesis Of Potential Dengue Virus NS2B-NS3 Protease Inhibitors
by: Sinha,, Suman
Published: (2018)

Synthesis, Characterization And Analgesic Activity Of Mitragynine Analogues
by: Ramlee, Nurul Izzati
Published: (2015)

Structure based drug design for antifungal agents (aspergillus niger) from synthesis of benzaldehyde derivatives
by: Abdul Razak., Ahmad Asraf
Published: (2015)

Genotoxicity Assessment Of Standardised Root Extract Of Eurycoma Longifolia Jack And Synthesis Of Some Benzimidazole Derivatives And Evaluation Of Their Anti-Cancer Potential
by: Muttiah, Nithya Niranjini
Published: (2013)

Effect Of Calcium Channel Blocker With Other Antihypertensive Agents On Lower Urinary Tract Symptoms And Its Impact On Patients’ Quality Of Life
by: Salman, Muhammad
Published: (2018)

Synthesis Of Blood-Brain Barrier Permeable Aurones As Modulators Of Microglia
by: Chia, Shi Yi
Published: (2023)

Green Synthesis Of Gold Nanoparticles As Photosensitizer For Phototherapy Breast Cancer Treatment
by: Al-Mafarjy, Sarah Shakir Mutar
Published: (2024)

The Heterogenization Of Sulfanilic And Sulfonic Acids And Their Catalytic Activity In The Liquidphase Alkylation Of Phenol
by: Hussein Ali, Tammar
Published: (2011)

Anticancer Studies Of Koetjapic Acid Purified From Sandoricum Koetjape MERR
by: Nassar, Zeyad D.
Published: (2011)

Synthesis And Evaluation Of Cross-Linked Disulphide Containing Polymers For Colonic Drug Delivery
by: Lim , Vuanghao
Published: (2009)

Synthesis And Application Of Molecularly Imprinted Solidphase Extraction For The Determination Of Terbutaline In Biological Matrices
by: Lim, Lay Lee
Published: (2006)

Effects Of Nigella sativa, Linoleic Acid And Eurycoma longifolia On Rabbit Penile Erection
by: Sahdom, Rosmiyani
Published: (2018)

Rational Design And Synthesis Of Inhibitors For H1n1 Neuraminidase And Dengue Protease Enzymes
by: Hariono, Maywan
Published: (2015)

Synthesis Of Molecularly Imprinted Polymer For Selective Solid-Phase Extraction Of Salbutamol From Urine Samples
by: Lee, Wei Inn
Published: (2011)

Synthesis, Cholinesterase Inhibitory Activity And Molecular Docking Study Of Piperidone-Grafted Pyrimidine And Thiazolopyrimidine Derivatives
by: Basiri, Alireza
Published: (2014)

Formulation And Evaluation Of Channa Striatus Extract And Fusidic Acid Aerosol For Treatment Of Wounds And Burn
by: Febriyenti, Febriyenti
Published: (2011)

Impact Of Insulin Containing Regimen Vs Triple Oral Hypoglycaemic Agent Therapy On Health-Related Quality Of Life, Economic, And Clinical Outcomes In Poorly Controlled Type 2 Diabetes Outpatients In Yogyakarta
by: Tri , Murti Andayani
Published: (2010)

The Development Of Rosmarinic Acid Derivatives To Target Il17a In Glioblastoma Multiforme Via Angiogenic Pathways
by: Khan, Md Shamsuddin Sultan
Published: (2017)

Synthesis And Characterization Of pH-Sensitive Polyelectrolyte Nanogels For Oral Delivery Of Bovine Serum Albumin And Insulin As Model Proteins
by: Mudassir, Jahanzeb
Published: (2018)