A study on patients requiring emergency hemodialysis in Hospital Universiti Sains Malaysia
Objective: It is currently unknown whether there are differences in patients' characteristics and hemodialysis (HD) outcomes between patients who undergo emergent HD in the emergency department (ED) and non-ED setting (i.e. ward, intensive care unit (ICU) or HD unit). Therefore, this study a...
| Main Author: | |
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| Format: | Thesis |
| Language: | English |
| Published: |
2020
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| Subjects: | |
| Online Access: | http://eprints.usm.my/60459/ http://eprints.usm.my/60459/1/NOOR%20AIDA%20ROSEDEE-E.pdf |
| _version_ | 1848884451849797632 |
|---|---|
| author | Rosedee, Noor Aida |
| author_facet | Rosedee, Noor Aida |
| author_sort | Rosedee, Noor Aida |
| building | USM Institutional Repository |
| collection | Online Access |
| description | Objective: It is currently unknown whether there are differences in patients' characteristics and
hemodialysis (HD) outcomes between patients who undergo emergent HD in the emergency
department (ED) and non-ED setting (i.e. ward, intensive care unit (ICU) or HD unit). Therefore,
this study aims to compare the clinical and non-clinical characteristics and HD outcomes between
patients who underwent emergent HD at ED (“ED group”) and non-ED (“non-ED group”) settings.
Methods: This is a retrospective observational study among patients admitted through the ED of
a tertiary teaching hospital in Malaysia and underwent acute HD within 24 hours of admission
between January 2016 till December 2017.
Results: A total of 177 patients were included in the study. The bivariable analysis found that the
ED group had a significantly higher proportion of new cases (i.e. no known history of HD), fluid
overload cases, and refractory fluid overload indication as compared to the non-ED group. It was
also found that the ED group had a higher proportion of those requiring mechanical ventilation
and 60-day mortality. Hierarchical regression found that HD locations play a significant role in
determining HD outcomes in terms of 60-days mortality and ICU stays. Those who underwent HD
at non-ED have 0.263 (95%CI=0.096, 0.723) times lower odds of 60-day mortality but 2.946
(95%CI=1.051, 8.258) times higher odds of staying in ICU.
Conclusion: There were significant differences in patients’ characteristics and HD outcomes
between patients underwent HD in ED and non-ED settings. Emergent HD location may influence 60-day mortality and ICU stays. As the current study is insufficient to confidently justify the use
of HD in ED settings as compared to the non-ED setting, a randomized controlled trial is needed. |
| first_indexed | 2025-11-15T19:06:55Z |
| format | Thesis |
| id | usm-60459 |
| institution | Universiti Sains Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T19:06:55Z |
| publishDate | 2020 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | usm-604592024-05-05T08:00:03Z http://eprints.usm.my/60459/ A study on patients requiring emergency hemodialysis in Hospital Universiti Sains Malaysia Rosedee, Noor Aida R Medicine RA440-440.87 Study and teaching. Research RC648-665 Diseases of the endocrine glands. Clinical endocrinology Objective: It is currently unknown whether there are differences in patients' characteristics and hemodialysis (HD) outcomes between patients who undergo emergent HD in the emergency department (ED) and non-ED setting (i.e. ward, intensive care unit (ICU) or HD unit). Therefore, this study aims to compare the clinical and non-clinical characteristics and HD outcomes between patients who underwent emergent HD at ED (“ED group”) and non-ED (“non-ED group”) settings. Methods: This is a retrospective observational study among patients admitted through the ED of a tertiary teaching hospital in Malaysia and underwent acute HD within 24 hours of admission between January 2016 till December 2017. Results: A total of 177 patients were included in the study. The bivariable analysis found that the ED group had a significantly higher proportion of new cases (i.e. no known history of HD), fluid overload cases, and refractory fluid overload indication as compared to the non-ED group. It was also found that the ED group had a higher proportion of those requiring mechanical ventilation and 60-day mortality. Hierarchical regression found that HD locations play a significant role in determining HD outcomes in terms of 60-days mortality and ICU stays. Those who underwent HD at non-ED have 0.263 (95%CI=0.096, 0.723) times lower odds of 60-day mortality but 2.946 (95%CI=1.051, 8.258) times higher odds of staying in ICU. Conclusion: There were significant differences in patients’ characteristics and HD outcomes between patients underwent HD in ED and non-ED settings. Emergent HD location may influence 60-day mortality and ICU stays. As the current study is insufficient to confidently justify the use of HD in ED settings as compared to the non-ED setting, a randomized controlled trial is needed. 2020 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/60459/1/NOOR%20AIDA%20ROSEDEE-E.pdf Rosedee, Noor Aida (2020) A study on patients requiring emergency hemodialysis in Hospital Universiti Sains Malaysia. Masters thesis, Universiti Sains Malaysia. |
| spellingShingle | R Medicine RA440-440.87 Study and teaching. Research RC648-665 Diseases of the endocrine glands. Clinical endocrinology Rosedee, Noor Aida A study on patients requiring emergency hemodialysis in Hospital Universiti Sains Malaysia |
| title | A study on patients requiring emergency hemodialysis in Hospital Universiti Sains Malaysia |
| title_full | A study on patients requiring emergency hemodialysis in Hospital Universiti Sains Malaysia |
| title_fullStr | A study on patients requiring emergency hemodialysis in Hospital Universiti Sains Malaysia |
| title_full_unstemmed | A study on patients requiring emergency hemodialysis in Hospital Universiti Sains Malaysia |
| title_short | A study on patients requiring emergency hemodialysis in Hospital Universiti Sains Malaysia |
| title_sort | study on patients requiring emergency hemodialysis in hospital universiti sains malaysia |
| topic | R Medicine RA440-440.87 Study and teaching. Research RC648-665 Diseases of the endocrine glands. Clinical endocrinology |
| url | http://eprints.usm.my/60459/ http://eprints.usm.my/60459/1/NOOR%20AIDA%20ROSEDEE-E.pdf |