Synthesis, Characterization, Cytotoxicity, And Antimicrobial Activity Of Azobenzene-Imidazolium Ionic Liquid Crystals
Four new series of azobenzene-imidazolium salts were synthesized by azo coupling, followed by alkylation and subsequent quaternization of N-alkylated imidazoles of various chain length with azobenzenes to afford the non-fluorinated (9a-9e), difluorinated (10a-10e) and tetrafluorinated (11a-11e, 12a-...
| Main Author: | |
|---|---|
| Format: | Thesis |
| Language: | English |
| Published: |
2023
|
| Subjects: | |
| Online Access: | http://eprints.usm.my/60431/ http://eprints.usm.my/60431/1/Pages%20from%20HALIMAH%20FUNMILAYO%20BABAMALE%20-%20TESIS.pdf |
| _version_ | 1848884443806171136 |
|---|---|
| author | Funmilayo, Babamale Halimah |
| author_facet | Funmilayo, Babamale Halimah |
| author_sort | Funmilayo, Babamale Halimah |
| building | USM Institutional Repository |
| collection | Online Access |
| description | Four new series of azobenzene-imidazolium salts were synthesized by azo coupling, followed by alkylation and subsequent quaternization of N-alkylated imidazoles of various chain length with azobenzenes to afford the non-fluorinated (9a-9e), difluorinated (10a-10e) and tetrafluorinated (11a-11e, 12a-12j) salts. The purity of the compounds was confirmed by CHN elemental analysis and their structures were elucidated using the FTIR, 1D and 2D NMR spectroscopies. The liquid crystalline (LC) properties of the salts were studied using the DSC and POM. In vitro cytotoxicity was explored using the MTT assay and their antimicrobial activities were investigated using the disc diffusion method. Smectic A (SmA) phase was observed in almost all compounds. |
| first_indexed | 2025-11-15T19:06:48Z |
| format | Thesis |
| id | usm-60431 |
| institution | Universiti Sains Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T19:06:48Z |
| publishDate | 2023 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | usm-604312024-04-26T07:15:40Z http://eprints.usm.my/60431/ Synthesis, Characterization, Cytotoxicity, And Antimicrobial Activity Of Azobenzene-Imidazolium Ionic Liquid Crystals Funmilayo, Babamale Halimah QD1-999 Chemistry Four new series of azobenzene-imidazolium salts were synthesized by azo coupling, followed by alkylation and subsequent quaternization of N-alkylated imidazoles of various chain length with azobenzenes to afford the non-fluorinated (9a-9e), difluorinated (10a-10e) and tetrafluorinated (11a-11e, 12a-12j) salts. The purity of the compounds was confirmed by CHN elemental analysis and their structures were elucidated using the FTIR, 1D and 2D NMR spectroscopies. The liquid crystalline (LC) properties of the salts were studied using the DSC and POM. In vitro cytotoxicity was explored using the MTT assay and their antimicrobial activities were investigated using the disc diffusion method. Smectic A (SmA) phase was observed in almost all compounds. 2023-04 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/60431/1/Pages%20from%20HALIMAH%20FUNMILAYO%20BABAMALE%20-%20TESIS.pdf Funmilayo, Babamale Halimah (2023) Synthesis, Characterization, Cytotoxicity, And Antimicrobial Activity Of Azobenzene-Imidazolium Ionic Liquid Crystals. PhD thesis, Universiti Sains Malaysia. |
| spellingShingle | QD1-999 Chemistry Funmilayo, Babamale Halimah Synthesis, Characterization, Cytotoxicity, And Antimicrobial Activity Of Azobenzene-Imidazolium Ionic Liquid Crystals |
| title | Synthesis, Characterization, Cytotoxicity, And Antimicrobial Activity Of Azobenzene-Imidazolium Ionic Liquid Crystals |
| title_full | Synthesis, Characterization, Cytotoxicity, And Antimicrobial Activity Of Azobenzene-Imidazolium Ionic Liquid Crystals |
| title_fullStr | Synthesis, Characterization, Cytotoxicity, And Antimicrobial Activity Of Azobenzene-Imidazolium Ionic Liquid Crystals |
| title_full_unstemmed | Synthesis, Characterization, Cytotoxicity, And Antimicrobial Activity Of Azobenzene-Imidazolium Ionic Liquid Crystals |
| title_short | Synthesis, Characterization, Cytotoxicity, And Antimicrobial Activity Of Azobenzene-Imidazolium Ionic Liquid Crystals |
| title_sort | synthesis, characterization, cytotoxicity, and antimicrobial activity of azobenzene-imidazolium ionic liquid crystals |
| topic | QD1-999 Chemistry |
| url | http://eprints.usm.my/60431/ http://eprints.usm.my/60431/1/Pages%20from%20HALIMAH%20FUNMILAYO%20BABAMALE%20-%20TESIS.pdf |