Ketum (Mitragyna Speciosa Korth.) Consumption, Lipid Profile And Electrocardiogram (Ecg) Abnormalities

Ketum (Mitragyna speciosa Korth.) a native medicinal plant of Southeast Asia, has been used in Malaysia for decades for its unique curative properties. Given its broad therapeutic properties and increasing utility, ketum’s long-term safety profile, especially on its cardiotoxicity risk remains po...

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Main Author: Korindasamy, Novline Yuvashnee
Format: Thesis
Language:English
Published: 2023
Subjects:
Online Access:http://eprints.usm.my/60344/
http://eprints.usm.my/60344/1/NOVLINE%20YUVASHNEE%20AP%20KORINDASAMY%20-%20TESIS%20convert%20cut.pdf
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author Korindasamy, Novline Yuvashnee
author_facet Korindasamy, Novline Yuvashnee
author_sort Korindasamy, Novline Yuvashnee
building USM Institutional Repository
collection Online Access
description Ketum (Mitragyna speciosa Korth.) a native medicinal plant of Southeast Asia, has been used in Malaysia for decades for its unique curative properties. Given its broad therapeutic properties and increasing utility, ketum’s long-term safety profile, especially on its cardiotoxicity risk remains poorly investigated in regular ketum users. Given this research limitation, this study aims to evaluate the electrocardiogram (ECG) abnormalities and lipid profile between regular ketum users and healthy control subjects. A total of 200 respondents (n=100 regular ketum users and n=100 healthy control subjects) were recruited through convenience sampling from the northern peninsular state of Penang for this clinical, cross-sectional study. All were required to undergo an ECG evaluation, and blood samples were also drawn to characterize the respondent’s lipid profile. All males, a majority were Malays (97%, n=194/200), and the samples mean age in this study was 33 years (SD=6.7), while ketum users mean duration of ketum use was 6.4 years (SD=4.31). Ketum users mean systolic and diastolic blood pressure rates were 132.9 beats per minute (SD=17.3) and 77.1 beats per minute (SD=11.1), respectively.
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spelling usm-603442024-04-03T07:43:01Z http://eprints.usm.my/60344/ Ketum (Mitragyna Speciosa Korth.) Consumption, Lipid Profile And Electrocardiogram (Ecg) Abnormalities Korindasamy, Novline Yuvashnee R735-854 Medical education. Medical schools. Research Ketum (Mitragyna speciosa Korth.) a native medicinal plant of Southeast Asia, has been used in Malaysia for decades for its unique curative properties. Given its broad therapeutic properties and increasing utility, ketum’s long-term safety profile, especially on its cardiotoxicity risk remains poorly investigated in regular ketum users. Given this research limitation, this study aims to evaluate the electrocardiogram (ECG) abnormalities and lipid profile between regular ketum users and healthy control subjects. A total of 200 respondents (n=100 regular ketum users and n=100 healthy control subjects) were recruited through convenience sampling from the northern peninsular state of Penang for this clinical, cross-sectional study. All were required to undergo an ECG evaluation, and blood samples were also drawn to characterize the respondent’s lipid profile. All males, a majority were Malays (97%, n=194/200), and the samples mean age in this study was 33 years (SD=6.7), while ketum users mean duration of ketum use was 6.4 years (SD=4.31). Ketum users mean systolic and diastolic blood pressure rates were 132.9 beats per minute (SD=17.3) and 77.1 beats per minute (SD=11.1), respectively. 2023-07 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/60344/1/NOVLINE%20YUVASHNEE%20AP%20KORINDASAMY%20-%20TESIS%20convert%20cut.pdf Korindasamy, Novline Yuvashnee (2023) Ketum (Mitragyna Speciosa Korth.) Consumption, Lipid Profile And Electrocardiogram (Ecg) Abnormalities. Masters thesis, Universiti Sains Malaysia.
spellingShingle R735-854 Medical education. Medical schools. Research
Korindasamy, Novline Yuvashnee
Ketum (Mitragyna Speciosa Korth.) Consumption, Lipid Profile And Electrocardiogram (Ecg) Abnormalities
title Ketum (Mitragyna Speciosa Korth.) Consumption, Lipid Profile And Electrocardiogram (Ecg) Abnormalities
title_full Ketum (Mitragyna Speciosa Korth.) Consumption, Lipid Profile And Electrocardiogram (Ecg) Abnormalities
title_fullStr Ketum (Mitragyna Speciosa Korth.) Consumption, Lipid Profile And Electrocardiogram (Ecg) Abnormalities
title_full_unstemmed Ketum (Mitragyna Speciosa Korth.) Consumption, Lipid Profile And Electrocardiogram (Ecg) Abnormalities
title_short Ketum (Mitragyna Speciosa Korth.) Consumption, Lipid Profile And Electrocardiogram (Ecg) Abnormalities
title_sort ketum (mitragyna speciosa korth.) consumption, lipid profile and electrocardiogram (ecg) abnormalities
topic R735-854 Medical education. Medical schools. Research
url http://eprints.usm.my/60344/
http://eprints.usm.my/60344/1/NOVLINE%20YUVASHNEE%20AP%20KORINDASAMY%20-%20TESIS%20convert%20cut.pdf