Inhibitory Effects Of Andrographolide In Pc-3 Cell Line And The Induction Of Apoptosis Via The Involvement Of Caspases 3, 8 And 9
Andrographolide is a labdane diterpenoid isolated from the plant Andrographis paniculata. This substance has numerous medicinal uses, notably anticancer effects. A previous study has revealed that andrographolide inhibits the growth of lung, brain, colon, and breast cancer cells. Due to a lack of re...
| Main Author: | Manimaran, Janany |
|---|---|
| Format: | Thesis |
| Language: | English |
| Published: |
2023
|
| Subjects: | |
| Online Access: | http://eprints.usm.my/60182/ http://eprints.usm.my/60182/1/24%20Pages%20from%20JANANY%20AP%20MANIMARAN.pdf |
Similar Items
Zerumbone induces apoptosis in Jurkat T-cell line via activation of caspase 3 and caspase 9
by: Rahman, Heshu Sulaiman, et al.
Published: (2012)
by: Rahman, Heshu Sulaiman, et al.
Published: (2012)
Andrographolide induces cell cycle arrest and apoptosis in PC-3 prostate cancer cells.
by: Hui, Chyn Wong, et al.
Published: (2011)
by: Hui, Chyn Wong, et al.
Published: (2011)
Cardamonin induces apoptosis in human nasopharyngeal carcinoma cells via mitochondrial death pathway mediated by caspase-3 and caspase-8 activation, independent of caspase-9 signalling responses
by: Chiang, Michelle
Published: (2016)
by: Chiang, Michelle
Published: (2016)
Caspase-3 and caspase-8 expression in breast cancer: caspase-3 is associated with survival
by: Xuan, Pu, et al.
Published: (2016)
by: Xuan, Pu, et al.
Published: (2016)
Antiproliferation and induction of caspase-8-dependent mitochondria-mediated apoptosis by β-tocotrienol in human lung and brain cancer cell lines
by: Lim, Su Wen, et al.
Published: (2014)
by: Lim, Su Wen, et al.
Published: (2014)
Induction of Caspase-2 Activation by a DNA Enzyme Evokes Tumor Cell Apoptosis
by: Kim, Soo-Hyun, et al.
Published: (2012)
by: Kim, Soo-Hyun, et al.
Published: (2012)
Caspase-8-mediated PAR-4 cleavage is required for TNFα-induced apoptosis
by: Treude, Fabian, et al.
Published: (2014)
by: Treude, Fabian, et al.
Published: (2014)
Caspases-3 and -7 are activated in goniothalamin-induced apoptosis in human Jurkat T-cells
by: Inayat-Hussain, Salmaan H., et al.
Published: (1999)
by: Inayat-Hussain, Salmaan H., et al.
Published: (1999)
Goniothalamin selectively induces apoptosis on human hepatoblastoma cells through caspase-3 activation.
by: Al-Qubaisi, Mothanna, et al.
Published: (2013)
by: Al-Qubaisi, Mothanna, et al.
Published: (2013)
3-Arylsydone and 4-Acetyl-3-Arylsydone: In vitro cytotoxicity against prostate cancer cell line (PC3), structure-activity relationship and in silico evaluation of their caspase 3 inhibition
by: Mohammed Abdualkader, Abdualrahman, et al.
Published: (2016)
by: Mohammed Abdualkader, Abdualrahman, et al.
Published: (2016)
Clausenidin induces caspase-dependent apoptosis in colon cancer
by: Waziri, Peter M., et al.
Published: (2016)
by: Waziri, Peter M., et al.
Published: (2016)
Induction of selective cytotoxicity and apoptosis in human T4-lymphoblastoid cell line (CEMss) by boesenbergin a isolated from boesenbergia rotunda rhizomes involves mitochondrial pathway, activation of caspase 3 and G2/M phase cell cycle arrest
by: Ng, Kuan Beng, et al.
Published: (2013)
by: Ng, Kuan Beng, et al.
Published: (2013)
Induction of cell cycle arrest and apoptosis in caspase-3 deficient MCF-7 cells by Dillenia suffruticosa root extract via multiple signalling pathways
by: Foo, Jhi Biau, et al.
Published: (2014)
by: Foo, Jhi Biau, et al.
Published: (2014)
Induction of cell cycle arrest and apoptosis in caspase-3 deficient MCF-7 cells by Dillenia suffruticosa root extract via multiple signaling pathways
by: Foo, Jhi Biau, et al.
Published: (2014)
by: Foo, Jhi Biau, et al.
Published: (2014)
Palmitic acid of Musa Paradisiaca induces apoptosis through caspase-3 in human oral squamous cell carcinoma
by: Budi, H. S., et al.
Published: (2022)
by: Budi, H. S., et al.
Published: (2022)
Water extract of brewers' rice induces apoptosis in human colorectal cancer cells via activation of caspase-3 and caspase-8 and downregulates the Wnt/β-catenin downstream signaling pathway in brewers' rice-treated rats with azoxymethane-induced colon carcinogenesis
by: Tan, Bee Ling, et al.
Published: (2015)
by: Tan, Bee Ling, et al.
Published: (2015)
Arborinine from Glycosmis Pentaphylla (retz.) DC induces apoptosis through activation of Caspase-3/7 in human mammary gland Adenocarcinoma (MCF-7) cell line
by: Mohd Hussain, Nurlaili Najmie, et al.
Published: (2016)
by: Mohd Hussain, Nurlaili Najmie, et al.
Published: (2016)
Loss of mitochondrial transmembrane potential and caspase-9 activation during apoptosis induced by the novel styryl-lactone goniothalamin in HL-60 leukemia cells
by: Inayat Hussain, Salmaan Hussain, et al.
Published: (2003)
by: Inayat Hussain, Salmaan Hussain, et al.
Published: (2003)
In vitro apoptosis induction and inhibition of NF-kB signaling pathway by biseugenol B in PC3 human prostatic cancer cells / Maryam Abbaspour Babaei
by: Maryam, Abbaspour Babaei
Published: (2018)
by: Maryam, Abbaspour Babaei
Published: (2018)
Apoptosis Activity and Mitogen Activated Protein Kinase
Expression of the Mouse Macrophage Cell Line J774a.1
Infected with a Recombinant Bcg Expressing the Cterminus of Merozoite Surface Protein-1
of Plasmodium Falciparum
by: Zulkipli, Anis Fadhilah
Published: (2016)
by: Zulkipli, Anis Fadhilah
Published: (2016)
The Role Of Caspase-Activated Dnase (Cad) In Chromosome Breaks During Oxidative Stressinduced Apoptosis
by: Boon, Siaw Shi
Published: (2009)
by: Boon, Siaw Shi
Published: (2009)
Antiproliferative And Apoptosis Effects Of Clinacanthus Nutans Leaf Extract On Breast Cancer Cell (Mcf7)
by: Ismail, Noor Zafirah
Published: (2023)
by: Ismail, Noor Zafirah
Published: (2023)
Crispr/Cas9-Mediated Suppression Of Dual-Specificity Phosphatase 6 (Dusp6) Inhibits Cell Viability, Growth, Survival And Adhesion In Ht-29 Human Colorectal Cancer Cell Line
by: Ahmad, Muhammad Khairi
Published: (2024)
by: Ahmad, Muhammad Khairi
Published: (2024)
Deciphering S-Phase Protein Kinase 2 (Skp2) Mediated Regulation Of Telomerase Reverse Transcriptase (Tert) In Kasumi-1, T (8;21) Acute Myeloid Leukemia (Aml) Cell Line
by: Rosli, Nur Aliaa Arina
Published: (2023)
by: Rosli, Nur Aliaa Arina
Published: (2023)
Induction of apoptosis in murine malignant mesothelioma cell lines: gene expression and susceptibility
by: Kusmiaty
Published: (2003)
by: Kusmiaty
Published: (2003)
Phorbol esters from Jatropha meal triggered apoptosis, activated PKC-δ, Caspase-3 proteins and down-regulated the proto-oncogenes in MCF-7 and HeLa cancer cell lines
by: Oskoueian, Ehsan, et al.
Published: (2012)
by: Oskoueian, Ehsan, et al.
Published: (2012)
Induction of Apoptosis by 2', 3’-Epoxyisocapnolactone and 8-Hydroxyisocapnolactone-2', 3’- Diol Isolated from Micromelum Minutum in Human T-Lymphocyte Leukemia Cem-Ss Cells
by: Tan, Boon Keat
Published: (2006)
by: Tan, Boon Keat
Published: (2006)
The growth suppressing effects of Girinimbine on Hepg2 involve induction of apoptosis and cell cycle arrest.
by: Syam, Suvitha, et al.
Published: (2011)
by: Syam, Suvitha, et al.
Published: (2011)
Combinatorial Crispr/Cas9 For Suppression Of Latent Hiv-1 Provirus In Vitro
by: Ravichantar, Nithya
Published: (2020)
by: Ravichantar, Nithya
Published: (2020)
Phosphorylation Of Human Interferon Regulatory Factor 9 During Type I Interferon Response
by: Anak Paul Joko, Alvin Dickson
Published: (2021)
by: Anak Paul Joko, Alvin Dickson
Published: (2021)
Induction of apoptosis in MCF-7 cells via oxidative stress generation, mitochondria-dependent and caspase-independent pathway by ethyl acetate extract of Dillenia suffruticosa and its chemical profile
by: Tor, Yin Sim, et al.
Published: (2015)
by: Tor, Yin Sim, et al.
Published: (2015)
Thymoquinone inhibits growth of human medulloblastoma cells by inducing oxidative stress and caspase-dependent apoptosis while suppressing NF-jB signaling and IL-8 expression
by: Ashour, Abdelkader Elbadawy Abbas, et al.
Published: (2016)
by: Ashour, Abdelkader Elbadawy Abbas, et al.
Published: (2016)
Mechanism Of Action Of A Benzimidazole Sirtuin Inhibitor, Bzd9l1, In Colorectal Cancer
by: Tan, Yi Jer
Published: (2022)
by: Tan, Yi Jer
Published: (2022)
The effect of letrozole (aromatase
inhibitorifemara) and clomiphene citrate
clomid/serophene) for induction of ovulation
in polycystic ovarian syndrome (PCOS)
by: Nik Hazlina, Nik Hussain
Published: (2012)
by: Nik Hazlina, Nik Hussain
Published: (2012)
Bzd9l1: Elucidation Of Its Anti-angiogenic Potential In In-vitro And In-vivo Colorectal Cancer Models
by: Subramaniam, Ayappa V.
Published: (2023)
by: Subramaniam, Ayappa V.
Published: (2023)
Mechanisms of cisplatin-induced cell death in malignant mesothelioma cells: Role of inhibitor of apoptosis proteins (IAPs) and caspases
by: Cregan, I., et al.
Published: (2013)
by: Cregan, I., et al.
Published: (2013)
Selective apoptosis induction in MCF-7cell line by truncated minimal functional region of Apoptin
by: Lim, Shen Ni, et al.
Published: (2013)
by: Lim, Shen Ni, et al.
Published: (2013)
Analysis Of OTUB1 Expression In Human Breast Adenocarcinoma Cell Line MCF7 And Human Breast Epithelial Cell Line MCF10A
by: Iskandar, Athirah
Published: (2019)
by: Iskandar, Athirah
Published: (2019)
Ficus auriculata (fig) extracts induced cell cycle profile changes and apoptosis through caspase-independent pathway in human LungAdenocarcinoma cell line, A549
by: Jamil, Elyna Fatini, et al.
Published: (2017)
by: Jamil, Elyna Fatini, et al.
Published: (2017)
Manilkara zapota (L.) P. Royen leaf water extract triggered apoptosis and activated caspase-dependent pathway in HT-29 human colorectal cancer cell line
by: Tan, Bee Ling, et al.
Published: (2019)
by: Tan, Bee Ling, et al.
Published: (2019)
Similar Items
-
Zerumbone induces apoptosis in Jurkat T-cell line via activation of caspase 3 and caspase 9
by: Rahman, Heshu Sulaiman, et al.
Published: (2012) -
Andrographolide induces cell cycle arrest and apoptosis in PC-3 prostate cancer cells.
by: Hui, Chyn Wong, et al.
Published: (2011) -
Cardamonin induces apoptosis in human nasopharyngeal carcinoma cells via mitochondrial death pathway mediated by caspase-3 and caspase-8 activation, independent of caspase-9 signalling responses
by: Chiang, Michelle
Published: (2016) -
Caspase-3 and caspase-8 expression in breast cancer: caspase-3 is associated with survival
by: Xuan, Pu, et al.
Published: (2016) -
Antiproliferation and induction of caspase-8-dependent mitochondria-mediated apoptosis by β-tocotrienol in human lung and brain cancer cell lines
by: Lim, Su Wen, et al.
Published: (2014)