Fabrication And Characterization Of Microcalcification Breast Phantom For Image Quality Analysis

This study aims to improve the early diagnosis of breast cancer through the application of image processing techniques based on the MATLAB algorithms to enhance the visibility of microcalcifications (MCs) in Full Field Digital Mammography (FFDM). Various polyvinyl alcohol (PVAL) composites phantoms...

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Main Author: Oyiwoja, Okoh Franca
Format: Thesis
Language:English
Published: 2022
Subjects:
Online Access:http://eprints.usm.my/59755/
http://eprints.usm.my/59755/1/24%20Pages%20from%20OKOH%20FRANCA%20OYIWOJA.pdf
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author Oyiwoja, Okoh Franca
author_facet Oyiwoja, Okoh Franca
author_sort Oyiwoja, Okoh Franca
building USM Institutional Repository
collection Online Access
description This study aims to improve the early diagnosis of breast cancer through the application of image processing techniques based on the MATLAB algorithms to enhance the visibility of microcalcifications (MCs) in Full Field Digital Mammography (FFDM). Various polyvinyl alcohol (PVAL) composites phantoms were produced through freezing and thawing method to mimic the physical and radiological properties of different categories of breast tissue in line with the BIRADS classification. The density, elemental composition, effective atomic number (Zeff), electron density (ꝭeff), mass attenuation coefficients of the PVAL-based phantoms and MC features (CaCO3/graphite) were determined. The microstructure and CT number of the PVAL were also studied. The 50/50 water/ethanol-based 10 wt% PVAL (E50), the water-based 10 wt% PVAL (P10), 10 wt% PVAL mixed with 4% graphite powder (G4), and the heterogeneous phantom (H) had physical and radiological properties suitable to mimic BIRADS B, C, D, and a heterogeneous breast tissue respectively. Phantom E50, P10, G4, and H recorded densities of 0.952 ± 0.011 g/cm3, 1.056 ± 0.002 g/cm3, 1.081 ± 0.002 g/cm3, and 1.025 ± 0.006 g/cm3 respectively, their Zeff and ꝭeff ranged from 7.148 to 7.418 and 3.189 X 1023/cm3 to 3.209 X 1023/cm3 respectively.
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language English
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spelling usm-597552024-01-22T06:20:15Z http://eprints.usm.my/59755/ Fabrication And Characterization Of Microcalcification Breast Phantom For Image Quality Analysis Oyiwoja, Okoh Franca QC1 Physics (General) This study aims to improve the early diagnosis of breast cancer through the application of image processing techniques based on the MATLAB algorithms to enhance the visibility of microcalcifications (MCs) in Full Field Digital Mammography (FFDM). Various polyvinyl alcohol (PVAL) composites phantoms were produced through freezing and thawing method to mimic the physical and radiological properties of different categories of breast tissue in line with the BIRADS classification. The density, elemental composition, effective atomic number (Zeff), electron density (ꝭeff), mass attenuation coefficients of the PVAL-based phantoms and MC features (CaCO3/graphite) were determined. The microstructure and CT number of the PVAL were also studied. The 50/50 water/ethanol-based 10 wt% PVAL (E50), the water-based 10 wt% PVAL (P10), 10 wt% PVAL mixed with 4% graphite powder (G4), and the heterogeneous phantom (H) had physical and radiological properties suitable to mimic BIRADS B, C, D, and a heterogeneous breast tissue respectively. Phantom E50, P10, G4, and H recorded densities of 0.952 ± 0.011 g/cm3, 1.056 ± 0.002 g/cm3, 1.081 ± 0.002 g/cm3, and 1.025 ± 0.006 g/cm3 respectively, their Zeff and ꝭeff ranged from 7.148 to 7.418 and 3.189 X 1023/cm3 to 3.209 X 1023/cm3 respectively. 2022-10 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/59755/1/24%20Pages%20from%20OKOH%20FRANCA%20OYIWOJA.pdf Oyiwoja, Okoh Franca (2022) Fabrication And Characterization Of Microcalcification Breast Phantom For Image Quality Analysis. PhD thesis, Perpustakaan Hamzah Sendut.
spellingShingle QC1 Physics (General)
Oyiwoja, Okoh Franca
Fabrication And Characterization Of Microcalcification Breast Phantom For Image Quality Analysis
title Fabrication And Characterization Of Microcalcification Breast Phantom For Image Quality Analysis
title_full Fabrication And Characterization Of Microcalcification Breast Phantom For Image Quality Analysis
title_fullStr Fabrication And Characterization Of Microcalcification Breast Phantom For Image Quality Analysis
title_full_unstemmed Fabrication And Characterization Of Microcalcification Breast Phantom For Image Quality Analysis
title_short Fabrication And Characterization Of Microcalcification Breast Phantom For Image Quality Analysis
title_sort fabrication and characterization of microcalcification breast phantom for image quality analysis
topic QC1 Physics (General)
url http://eprints.usm.my/59755/
http://eprints.usm.my/59755/1/24%20Pages%20from%20OKOH%20FRANCA%20OYIWOJA.pdf