Design, Synthesis, Biological Evaluation, And Molecular Docking Studies Of Ortho-Carboxamido Stilbenes As Anti-Diabetic And Anti-Proliferative Agents
A total of eleven ortho-carboxamido stilbenes (50a-50k) in 63-83 % yield have been synthesized using our modified Heck coupling method, and characterized using FT-IR, NMR, and HRMS. The research started with the Wittig reaction of 3,5-dimethoxybenzaldehyde (45) and methyltriphenylphosphonium iodide...
| Main Author: | Mohamad, Norhadi |
|---|---|
| Format: | Thesis |
| Language: | English |
| Published: |
2022
|
| Subjects: | |
| Online Access: | http://eprints.usm.my/59726/ http://eprints.usm.my/59726/1/Pages%20from%20NORHADI%20BIN%20MOHAMAD%20-%20TESIS%20cut.pdf |
Similar Items
Synthesis, Characterisation And Molecular Docking Of Quinoxaline-isoxazole Hybrids As Potential Anti-hyperglycemic Agent
by: Phongphane, Lacksany
Published: (2024)
by: Phongphane, Lacksany
Published: (2024)
Design, Synthesis, Molecular
Docking And Cytotoxic Activity Of
New Ortho-Hydroxy Chalcone And
Pyrazoline Derivatives
by: Luhaibi, Maadh Jumaah Owaid
Published: (2019)
by: Luhaibi, Maadh Jumaah Owaid
Published: (2019)
Synthesis, Characterization And In Vitro Potency Of Di-, Tri-, And Tetra-Substituted Stilbene Derivatives As Vasorelaxant
by: Chan, Sock Ying
Published: (2021)
by: Chan, Sock Ying
Published: (2021)
Isolation, Characterization, Anti-Hyperglycemic Activity And Molecular Docking Studies Of Constituents Isolated From Endiandra Kingiana And Beilschmiedia Lumutensis (Lauraceae)
by: Saad, Nur Amirah
Published: (2022)
by: Saad, Nur Amirah
Published: (2022)
Anti-proliferative, apoptotic induction, and anti-migration effects of hemi-synthetic 1′S-1′-acetoxychavicol acetate analogs on MDA-MB-231 breast cancer cells
by: Su, Ki Liew, et al.
Published: (2017)
by: Su, Ki Liew, et al.
Published: (2017)
Molecular docking and in silico evaluation of phytochemicals of bioactive methanolic extract of Ipomoea mauritiana Jacq. as anti-bacterial agents
by: Roney, Miah, et al.
Published: (2022)
by: Roney, Miah, et al.
Published: (2022)
Identification of anti-proliferative kinase inhibitors as potential therapeutic agents to treat canine osteosarcoma
by: Mauchle, Ulrike, et al.
Published: (2015)
by: Mauchle, Ulrike, et al.
Published: (2015)
Design, synthesis, and biological evaluation of novel arylcarboxamide derivatives as anti-tubercular agents
by: Alsayed, Shahinda SR, et al.
Published: (2020)
by: Alsayed, Shahinda SR, et al.
Published: (2020)
Synthesis and biological evaluation of heterocyclic analogues of pregnenolone as novel anti-osteoporotic agents
by: Maurya, S., et al.
Published: (2017)
by: Maurya, S., et al.
Published: (2017)
Synthesis, Cytotoxicity Study, And Molecular Docking Of New Imidazole-Based Chalcone And Pyrazoline Hybrids
by: Bakar, Bazri Izwan
Published: (2023)
by: Bakar, Bazri Izwan
Published: (2023)
Synthesis and reactions of halogenated stilbenes mediated by Lewis acid and QSAR studies of stilbene analogues / Mohd Fadzli Md Din
by: Mohd Fadzli , Md Din
Published: (2016)
by: Mohd Fadzli , Md Din
Published: (2016)
Porcupine bezoar: in vitro antioxidant and anti-proliferative effects
by: Abdullah Asuhaimi, Faizah, et al.
Published: (2017)
by: Abdullah Asuhaimi, Faizah, et al.
Published: (2017)
Molecular docking studies on the interaction of anti-alzheimer compounds with amyloid beta peptides
by: Faujan, Nur Hana, et al.
Published: (2019)
by: Faujan, Nur Hana, et al.
Published: (2019)
Integrative biological studies of anti-tumour agents
by: Johnson, L.A.
Published: (2009)
by: Johnson, L.A.
Published: (2009)
Synthesis and Biological Evaluation of Anti-Parasitic Compounds
by: Gallagher, Ashlee
Published: (2024)
by: Gallagher, Ashlee
Published: (2024)
Proximate analysis and anti-proliferative properties of vitex negundo L.
by: Rabeta Mohd Salleh,, et al.
Published: (2014)
by: Rabeta Mohd Salleh,, et al.
Published: (2014)
Anti-proliferative and anti-invasive properties of a purified fraction from Streptomyces sp. H7372.
by: Yip, Wai Kien, et al.
Published: (2010)
by: Yip, Wai Kien, et al.
Published: (2010)
Design, Synthesis and Biological Evaluation of Novel Indole-2-Carboxamide Derivatives as Anti-Tubercular Agents
by: Alsayed, Shahinda Sayed Rabie
Published: (2021)
by: Alsayed, Shahinda Sayed Rabie
Published: (2021)
Synthesis, Characterization And Anti-Proliferation Study Of Some Benzimidazole Derivatives
by: al-Douh, Mohammed Hadi Saeed
Published: (2010)
by: al-Douh, Mohammed Hadi Saeed
Published: (2010)
Molecular Docking And Molecular Dynamics Of 3-O-Octanoylcatechin Interactions Against Aldose Reductase
by: Soib’, Shikin Faezah
Published: (2019)
by: Soib’, Shikin Faezah
Published: (2019)
Evaluation of the anti-proliferative and antimicrobial activities of three types of trigona spp. honey
by: Zaib, Nik Amalia Nasratiena Mat
Published: (2018)
by: Zaib, Nik Amalia Nasratiena Mat
Published: (2018)
Anti-diabetic activity of phloretin against maltase-glucoamylase using docking, pharmacokinetics and pharmacophore studies
by: Roney, Miah, et al.
Published: (2023)
by: Roney, Miah, et al.
Published: (2023)
Isolation and anti-proliferative activity of natural products from green seaweed
by: Zulhedi Ilyas, Fitriyanti, et al.
Published: (2014)
by: Zulhedi Ilyas, Fitriyanti, et al.
Published: (2014)
Antioxidant, anti-inflammatory and anti-proliferative effects of methanolic leaf extract of Muntingia calabura L. on colon cancer
by: Md Nasir, Nur Liana
Published: (2017)
by: Md Nasir, Nur Liana
Published: (2017)
Docking And Molecular Dynamics Simulation Studies Of Insulin-Β-Cyclodextrin Interactions
by: Muhammad, Erma Fatiha
Published: (2016)
by: Muhammad, Erma Fatiha
Published: (2016)
Docking And Molecular Dynamics
Simulation Studies Of Insulin-P-
Cyclodextrin Interactions
by: Muhammad, Erma Fatiha
Published: (2016)
by: Muhammad, Erma Fatiha
Published: (2016)
Synthesis And Molecular Docking Studies Of New Phenylisoxazole Quinoxaline-2-Amine Hybrids As Potential Α Amylase And Α-Glucosidase Inhibitors
by: Radzuan, Siti Nurshahira Mohd
Published: (2024)
by: Radzuan, Siti Nurshahira Mohd
Published: (2024)
A review on the formulation and analysis of anti-diabetic agent: Gliclazide
by: Helal Uddin, A.B.M., et al.
Published: (2013)
by: Helal Uddin, A.B.M., et al.
Published: (2013)
Synthesis and biological evaluation of curcumin-like diarylpentanoid analogues for anti-inflammatory, antioxidant and anti-tyrosinase activities
by: Ka-Heng, Lee, et al.
Published: (2009)
by: Ka-Heng, Lee, et al.
Published: (2009)
Design, Synthesis and Molecular Docking Studies of Some Novel Spiro Derivatives By 1,3-Cycloaddition Reaction
by: Hasmaruddin, Nurul Syazana, et al.
Published: (2016)
by: Hasmaruddin, Nurul Syazana, et al.
Published: (2016)
Development of a new class of diarylpentadienone analogues as anti-diabetic agents
by: Abdullah, Maryam Aisyah
Published: (2019)
by: Abdullah, Maryam Aisyah
Published: (2019)
Calophyllum inophyllum and Calophyllum soulattri source of anti-proliferative xanthones and their structure-activity relationships
by: Mah, Siau Hui, et al.
Published: (2015)
by: Mah, Siau Hui, et al.
Published: (2015)
Cytotoxic, anti-proliferative and apoptotic effects of zerumbone on human and mouse leukemic cell lines
by: Hamid, Asmah
Published: (2010)
by: Hamid, Asmah
Published: (2010)
Goat’s Milk as a Potential Anti-proliferative against Colon Cancer Cell Lines
Synthesis, spectral characterization and biological
activities of Organotin(IV) complexes with ortho-vanillin-2-hydrazinopyridine (VHP)
by: Norrihan, Sam, et al.
Published: (2012)
by: Norrihan, Sam, et al.
Published: (2012)
Synthesis and biological evaluation of novel anti-tumour (E)-styrylsulfonyl methylpyridines
by: Lu, Tiangong
Published: (2014)
by: Lu, Tiangong
Published: (2014)
Discovery and evaluation of anti-cancer agents
by: Lam, Fong Ki
Published: (2010)
by: Lam, Fong Ki
Published: (2010)
Cytotoxicity, antimutagenicity and molecular docking of benzimidazole derivatives as anticancer agents
by: Azahar, Nurul Hafizan
Published: (2021)
by: Azahar, Nurul Hafizan
Published: (2021)
Molecular docking
by: Abduallah Alsafi, Hassen Mohammed, et al.
Published: (2011)
by: Abduallah Alsafi, Hassen Mohammed, et al.
Published: (2011)
Succinic acid para-aminobenzoyl hydrazide as anti-diabetic agent with immunomodulating properties
by: Dolzhenko, Anton, et al.
Published: (2007)
by: Dolzhenko, Anton, et al.
Published: (2007)
Similar Items
-
Synthesis, Characterisation And Molecular Docking Of Quinoxaline-isoxazole Hybrids As Potential Anti-hyperglycemic Agent
by: Phongphane, Lacksany
Published: (2024) -
Design, Synthesis, Molecular
Docking And Cytotoxic Activity Of
New Ortho-Hydroxy Chalcone And
Pyrazoline Derivatives
by: Luhaibi, Maadh Jumaah Owaid
Published: (2019) -
Synthesis, Characterization And In Vitro Potency Of Di-, Tri-, And Tetra-Substituted Stilbene Derivatives As Vasorelaxant
by: Chan, Sock Ying
Published: (2021) -
Isolation, Characterization, Anti-Hyperglycemic Activity And Molecular Docking Studies Of Constituents Isolated From Endiandra Kingiana And Beilschmiedia Lumutensis (Lauraceae)
by: Saad, Nur Amirah
Published: (2022) -
Anti-proliferative, apoptotic induction, and anti-migration effects of hemi-synthetic 1′S-1′-acetoxychavicol acetate analogs on MDA-MB-231 breast cancer cells
by: Su, Ki Liew, et al.
Published: (2017)