Genetic determinants excluding GBCR::ABL mutations of imatinib mesylate therapy response among chronic myeloid leukaemia patients in Malaysia
Despite imatinib mesylate (IM) being the frontline drug for successful treatment of chronic myeloid leukaemia (CML), a significant proportion of CML patients on IM therapy develop resistance and attain poor outcome. The objective of the present study was to investigate the contribution of selecte...
| Main Author: | Ismail, Siti Mariam |
|---|---|
| Format: | Thesis |
| Language: | English |
| Published: |
2023
|
| Subjects: | |
| Online Access: | http://eprints.usm.my/58908/ http://eprints.usm.my/58908/1/SITI%20MARIAM%20ISMAIL%20-FINAL%20THESIS%20S-UD000420%28R%29%2024%20pages.pdf |
Similar Items
Detection of PDGFRA mutations at exons 12 and 18 among chronic myeloid leukemia patients treated with imatinib mesylate
by: Razali, Ruzi Hamimi
Published: (2015)
by: Razali, Ruzi Hamimi
Published: (2015)
Contribution of BCR-ABL kinase domain mutations to imatinib mesylate resistance in Philadelphia chromosome positive Malaysian chronic myeloid leukemia patients
by: Elias, Marjanu Hikmah, et al.
Published: (2012)
by: Elias, Marjanu Hikmah, et al.
Published: (2012)
Determination of gene copy number status in tert and terc among chronic myeloid leukaemia patients resist ant and responsive to imatinib mesylate treatment
by: Asrari, Zaidatul Shakila Mohamad
Published: (2014)
by: Asrari, Zaidatul Shakila Mohamad
Published: (2014)
Detection of BCR-ABL T315i mutation in imatinib resistant chronic myeloid leukemia patients
by: Mardziah M,, et al.
Published: (2019)
by: Mardziah M,, et al.
Published: (2019)
Application of high resolution melting (HRM) analysis in detection of PDGFRA gene mutations among chronic myeloid leukemia patients treated with imanitib mesylate
by: Rashid, Nur Sabrina Abd
Published: (2020)
by: Rashid, Nur Sabrina Abd
Published: (2020)
Influence of tert gene expression, telomerase activity and telomere length in relation to imatinib mesylate resistance in Malaysian chronic myeloid leukaemia patients
by: Shamshudin, Wati @ Hayati Mohd
Published: (2020)
by: Shamshudin, Wati @ Hayati Mohd
Published: (2020)
Disease acceptance and adherence to imatinib in Taiwanese chronic myeloid leukaemia outpatients
by: Chen, Li-Chia, et al.
Published: (2014)
by: Chen, Li-Chia, et al.
Published: (2014)
Molecular genetic and epigenetic mechanisms of primary and secondary resistance to imatinib mesylate treatment in ph chromosome positive chronic myeloid leukemia patients
by: Elias, Marjanu Hikmah
Published: (2015)
by: Elias, Marjanu Hikmah
Published: (2015)
Influence of ORM1, PXR, CAR, CYP3A4 and CYP3A5 gene polymorphisms in mediating susceptibility risk to chronic myeloid leukaemia and response to imatinib mesylate therapy
by: Maddin, Najlaa
Published: (2017)
by: Maddin, Najlaa
Published: (2017)
Molecular basis of primary and secondary
resistance to imatinib mesylate
by: Abdul Aziz, Baba
Published: (2012)
by: Abdul Aziz, Baba
Published: (2012)
Imatinab mesylate treatment in Chronic Myeloid
Leukemia (CML)- understanding the
fundamental pharmacokinetic and
pharmacogenetic mechanisms for variation in
response
by: Ankathil, Ravindran
Published: (2016)
by: Ankathil, Ravindran
Published: (2016)
Detection of BCR/ABL gene in chronic Myeloid Leukaemia: comparison of Fluorescence in situ Hybridisation (FISH), conventional Cytogenetics and Polymerase Chain Reaction (PCR) techniques
by: Reena RMZ,, et al.
Published: (2006)
by: Reena RMZ,, et al.
Published: (2006)
Donor chimerism and bcr-abl gene status following non-myeloablative peripheral blood stem cell transplantation in chronic myeloid leukaemia patients in HUKM
by: Seman, Zainina, et al.
Published: (2008)
by: Seman, Zainina, et al.
Published: (2008)
FLT3, NPM1, DNMT3a and NRAS genes mutation in acute myeloid leukaemia in HUSM
by: Mat Yunus, Noraini
Published: (2015)
by: Mat Yunus, Noraini
Published: (2015)
Ultra-high performance liquid chromatography
(uhplc) method development and validation for the
determination of serum imatinib and its active
metabolite concentration among chronic myeloid
leukemia patients
by: Liong, Tan Ka
Published: (2013)
by: Liong, Tan Ka
Published: (2013)
Survival rate and prognostic factors of survival among chronic myeloid leukaemia adults after initiation of tyrosine kinase inhibitor therapy in Hospital Ampang, Selangor
by: Ali, Zakiah Bakar
Published: (2024)
by: Ali, Zakiah Bakar
Published: (2024)
C-kit Inhibition by Imatinib Mesylate Attenuates Progenitor Cell Expansion and Inhibits Liver Tumor Formation in Mice
by: Knight, B., et al.
Published: (2008)
by: Knight, B., et al.
Published: (2008)
Incidence of c-Cbl mutations in human acute myeloid leukaemias in an Australian patient cohort
by: Ghassemifar, Reza, et al.
Published: (2011)
by: Ghassemifar, Reza, et al.
Published: (2011)
The immunotype of acute leukaemia in Kelantan as determined by flow cytometry
by: Dasgupta, Anil, et al.
Published: (1999)
by: Dasgupta, Anil, et al.
Published: (1999)
Use of flowcytometric immunophenotyping in the diagnosis and prognosis of acute leukaemias in Sarawak
by: Voon, Ah Kim
Published: (2004)
by: Voon, Ah Kim
Published: (2004)
Targeting dormancy in acute myeloid leukaemia
by: Doolan, Lara
Published: (2023)
by: Doolan, Lara
Published: (2023)
The cytotoxicity effect of ant-444 in human chronic myeloid leukaemia cells (K 562)
by: Khalid, Nor Bahijah, et al.
Published: (2013)
by: Khalid, Nor Bahijah, et al.
Published: (2013)
DNA damage response and anti-apoptotic proteins expression in NPMc+ mutated cells in acute myeloid leukaemia
by: Qutob, Haitham
Published: (2014)
by: Qutob, Haitham
Published: (2014)
Cytogenomic profiling of chronic lymphocytic leukaemia patients using dna microarray
by: Zamri, Wan Norizzati Wan Mohamad
Published: (2021)
by: Zamri, Wan Norizzati Wan Mohamad
Published: (2021)
The Clinical Significance Of Npm1, Flt3 And Cebpa Gene Mutations In Adult Patients With Acute Myeloid Leukaemia
by: Ul Haq, Izaz
Published: (2020)
by: Ul Haq, Izaz
Published: (2020)
Epidermal growth factor receptor (EGFR) mutations are the main oncogenic driver mutation in adenocarcinoma in never-smokers - findings from the emlan study
by: Liam, Chong Kin, et al.
Published: (2012)
by: Liam, Chong Kin, et al.
Published: (2012)
Gene Expression Profile And Modulation Of
Genetic Pathways In Acute Myeloid
Leukaemia T(8;21)
by: Bashanfer, Salem Ali Alsalem
Published: (2013)
by: Bashanfer, Salem Ali Alsalem
Published: (2013)
Identifying and targeting dormant cells in acute myeloid leukaemia
by: Yu, N.
Published: (2016)
by: Yu, N.
Published: (2016)
Less utilized prognostic markers in acute myeloid leukaemia
by: Abdullah, Maha
Published: (2016)
by: Abdullah, Maha
Published: (2016)
ENPP4 and HOXA3 as potential leukaemia stem cell markers in acute myeloid leukaemia
by: Mohd Amin, A, et al.
Published: (2023)
by: Mohd Amin, A, et al.
Published: (2023)
Genome-wide analysis for genomic alteration in
acute promyelocytic leukaemia
by: Hassan, Rosline
Published: (2017)
by: Hassan, Rosline
Published: (2017)
Recent advances in diagnosis of acute myeloid leukaemia : a review.
by: Ambayya, Angeli, et al.
Published: (2013)
by: Ambayya, Angeli, et al.
Published: (2013)
Proteomic profile of acute myeloid leukaemia: a review update
by: Almaiman, Amer Abdulrahman, et al.
Published: (2016)
by: Almaiman, Amer Abdulrahman, et al.
Published: (2016)
Identification of differentially expressed proteins as biomarkers of acute myeloid leukaemia
by: Barantalab, Fatemeh
Published: (2014)
by: Barantalab, Fatemeh
Published: (2014)
Selection of reference genes for quantitative studies in acute myeloid leukaemia
by: Lee, Cindee, et al.
Published: (2019)
by: Lee, Cindee, et al.
Published: (2019)
Genotype-phenotype study of tuberous sclerosis complex in selected cohort of Malaysian patients with TSC2 mutations
by: Ismail, Nur Farrah Dila
Published: (2015)
by: Ismail, Nur Farrah Dila
Published: (2015)
Effects of nicotinamide and nilotinib on telomerase activity and telomere length associated with parp-1 regulation in k562 myeloid cell line
by: Muhammad, Nur Rasyidah
Published: (2023)
by: Muhammad, Nur Rasyidah
Published: (2023)
Characteristics of epidermal growth factor receptor (EGFR)-Mutated Non Small Cell Lung Carcinoma (NSCLC)-patients who developed resistance to first or second generation Egfrtyrosine Kinase Inhibitor (TKI) Therapy through T790M mutation / Vijayan Munusamy
by: Vijayan, Munusamy
Published: (2017)
by: Vijayan, Munusamy
Published: (2017)
Influence of gene mutations on inflammation, oxidative stress and endothelial function in patients with familial hypercholesterolaemia / Prof. Dr. Hapizah Mohd Nawawi … [et al.]
by: Mohd Nawawi, Hapizah, et al.
Published: (2010)
by: Mohd Nawawi, Hapizah, et al.
Published: (2010)
Moringa oleifera leaf ethanol extract immunomodulatory activity discriminates between chronic myeloid leukaemia cell line and normal lymphocytes
by: Lawal, Hamza, et al.
Published: (2022)
by: Lawal, Hamza, et al.
Published: (2022)
Similar Items
-
Detection of PDGFRA mutations at exons 12 and 18 among chronic myeloid leukemia patients treated with imatinib mesylate
by: Razali, Ruzi Hamimi
Published: (2015) -
Contribution of BCR-ABL kinase domain mutations to imatinib mesylate resistance in Philadelphia chromosome positive Malaysian chronic myeloid leukemia patients
by: Elias, Marjanu Hikmah, et al.
Published: (2012) -
Determination of gene copy number status in tert and terc among chronic myeloid leukaemia patients resist ant and responsive to imatinib mesylate treatment
by: Asrari, Zaidatul Shakila Mohamad
Published: (2014) -
Detection of BCR-ABL T315i mutation in imatinib resistant chronic myeloid leukemia patients
by: Mardziah M,, et al.
Published: (2019) -
Application of high resolution melting (HRM) analysis in detection of PDGFRA gene mutations among chronic myeloid leukemia patients treated with imanitib mesylate
by: Rashid, Nur Sabrina Abd
Published: (2020)