Comparison Between Transcutaneous and Total Serum Bilirubin Measurement in Malay Neonates

Background: Transcutaneous bilirubinometer is a portable, painless and non-invasive device to measure bilirubin. This study aims to investigate the reliability of Dräger Jaundice Meter JM-105 for the screening of neonatal jaundice in Malay neonates. Methods: Prospective cross-sectional study cond...

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Main Author: Mohamed, Mazrah
Format: Thesis
Language:English
Published: 2021
Subjects:
Online Access:http://eprints.usm.my/58850/
http://eprints.usm.my/58850/1/MAZRAH%20BINTI%20MOHAMED-24%20pages.pdf
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author Mohamed, Mazrah
author_facet Mohamed, Mazrah
author_sort Mohamed, Mazrah
building USM Institutional Repository
collection Online Access
description Background: Transcutaneous bilirubinometer is a portable, painless and non-invasive device to measure bilirubin. This study aims to investigate the reliability of Dräger Jaundice Meter JM-105 for the screening of neonatal jaundice in Malay neonates. Methods: Prospective cross-sectional study conducted in a tertiary university hospital involving 130 jaundiced neonates who required serum bilirubin determination from day 2 to day 7 of life. Paired bilirubin samples of total serum bilirubin (TSB) and transcutaneous bilirubin (TcB) were obtained. TcB were measured at the neonates’ forehead and sternum. The TcB were measured using JM-105. Results: There were 130 paired samples of TSB and TcB. The mean TSB was 232 μmol/L. The mean TcB measured at forehead and sternum were 222 μmol/L and 223 μmol/L, respectively. The mean difference between TSB and TcB was 10 μmol/L at forehead and 9 μmol/L at sternum. Strong positive correlation between TSB with mean TcB forehead (r=0.82) and TcB sternum (r=0.80), and strong correlation (r=0.91) between TcB forehead and TcB sternum. Conclusion: Our study demonstrated strong correlation between TcB values and TSB values. TcB measured at forehead or sternum is a good alternative as a non-invasive screening tool for non-severe hyperbilirubinemia in Malay neonates.
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spelling usm-588502023-07-06T06:46:26Z http://eprints.usm.my/58850/ Comparison Between Transcutaneous and Total Serum Bilirubin Measurement in Malay Neonates Mohamed, Mazrah RJ Pediatrics Background: Transcutaneous bilirubinometer is a portable, painless and non-invasive device to measure bilirubin. This study aims to investigate the reliability of Dräger Jaundice Meter JM-105 for the screening of neonatal jaundice in Malay neonates. Methods: Prospective cross-sectional study conducted in a tertiary university hospital involving 130 jaundiced neonates who required serum bilirubin determination from day 2 to day 7 of life. Paired bilirubin samples of total serum bilirubin (TSB) and transcutaneous bilirubin (TcB) were obtained. TcB were measured at the neonates’ forehead and sternum. The TcB were measured using JM-105. Results: There were 130 paired samples of TSB and TcB. The mean TSB was 232 μmol/L. The mean TcB measured at forehead and sternum were 222 μmol/L and 223 μmol/L, respectively. The mean difference between TSB and TcB was 10 μmol/L at forehead and 9 μmol/L at sternum. Strong positive correlation between TSB with mean TcB forehead (r=0.82) and TcB sternum (r=0.80), and strong correlation (r=0.91) between TcB forehead and TcB sternum. Conclusion: Our study demonstrated strong correlation between TcB values and TSB values. TcB measured at forehead or sternum is a good alternative as a non-invasive screening tool for non-severe hyperbilirubinemia in Malay neonates. 2021 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/58850/1/MAZRAH%20BINTI%20MOHAMED-24%20pages.pdf Mohamed, Mazrah (2021) Comparison Between Transcutaneous and Total Serum Bilirubin Measurement in Malay Neonates. Masters thesis, Universiti Sains Malaysia.
spellingShingle RJ Pediatrics
Mohamed, Mazrah
Comparison Between Transcutaneous and Total Serum Bilirubin Measurement in Malay Neonates
title Comparison Between Transcutaneous and Total Serum Bilirubin Measurement in Malay Neonates
title_full Comparison Between Transcutaneous and Total Serum Bilirubin Measurement in Malay Neonates
title_fullStr Comparison Between Transcutaneous and Total Serum Bilirubin Measurement in Malay Neonates
title_full_unstemmed Comparison Between Transcutaneous and Total Serum Bilirubin Measurement in Malay Neonates
title_short Comparison Between Transcutaneous and Total Serum Bilirubin Measurement in Malay Neonates
title_sort comparison between transcutaneous and total serum bilirubin measurement in malay neonates
topic RJ Pediatrics
url http://eprints.usm.my/58850/
http://eprints.usm.my/58850/1/MAZRAH%20BINTI%20MOHAMED-24%20pages.pdf