Biomems: Thermal Effects Analysis Of DNA Cocktail Solution (DCS) In A Microfluidic Channel
BioMEMS and microfluidics technology are two areas of MEMS based application, which has found a lot of new grounds in the fields of medicine and health sciences. In a related development Polymerase Chain Reaction (PCR) is one of the areas where microfluidics MEMS can be applied. There are poss...
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| Format: | Monograph |
| Language: | English |
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Universiti Sains Malaysia
2005
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| Online Access: | http://eprints.usm.my/58167/ http://eprints.usm.my/58167/1/Biomems%20Thermal%20Effects%20Analysis%20Of%20DNA%20Cocktail%20Solution%20%28DCS%29%20In%20A%20Microfluidic%20Channel.pdf |
| _version_ | 1848883824816029696 |
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| author | Khor, Hee Huat |
| author_facet | Khor, Hee Huat |
| author_sort | Khor, Hee Huat |
| building | USM Institutional Repository |
| collection | Online Access |
| description | BioMEMS and microfluidics technology are two areas of MEMS based application,
which has found a lot of new grounds in the fields of medicine and health sciences. In
a related development Polymerase Chain Reaction (PCR) is one of the areas where
microfluidics MEMS can be applied. There are possibly a lot of new benefits such as
reducing consumption of DNA cocktail solution (DCS), improving reliability,
reducing the time it takes to complete the PCR process, using less power etc. A
simulation of thermal analysis on static DCS in a single microfluidic channel under
different conditions that includes environment and parametric changes are presented
in this thesis. The analysis software ANSYS allows the creation of a simplified
simulation model and also the thermal analysis of the model under the required
conditions. The analyses include variation of heat generated from heater, change of
ambient temperature and convection and also reduction of the heater size. All of
which are analyzed under a no-flow condition environment with specific temperature
ranges where the denaturing process and DCS is considered to be working optimally.
The results are able to achieve the objectives and also to concur some of the theory
presented from the literature. Besides that some new conclusive information on
thermal effects due to parametric changes are also presented in this thesis. |
| first_indexed | 2025-11-15T18:56:57Z |
| format | Monograph |
| id | usm-58167 |
| institution | Universiti Sains Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T18:56:57Z |
| publishDate | 2005 |
| publisher | Universiti Sains Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | usm-581672023-04-20T05:28:47Z http://eprints.usm.my/58167/ Biomems: Thermal Effects Analysis Of DNA Cocktail Solution (DCS) In A Microfluidic Channel Khor, Hee Huat T Technology TJ Mechanical engineering and machinery BioMEMS and microfluidics technology are two areas of MEMS based application, which has found a lot of new grounds in the fields of medicine and health sciences. In a related development Polymerase Chain Reaction (PCR) is one of the areas where microfluidics MEMS can be applied. There are possibly a lot of new benefits such as reducing consumption of DNA cocktail solution (DCS), improving reliability, reducing the time it takes to complete the PCR process, using less power etc. A simulation of thermal analysis on static DCS in a single microfluidic channel under different conditions that includes environment and parametric changes are presented in this thesis. The analysis software ANSYS allows the creation of a simplified simulation model and also the thermal analysis of the model under the required conditions. The analyses include variation of heat generated from heater, change of ambient temperature and convection and also reduction of the heater size. All of which are analyzed under a no-flow condition environment with specific temperature ranges where the denaturing process and DCS is considered to be working optimally. The results are able to achieve the objectives and also to concur some of the theory presented from the literature. Besides that some new conclusive information on thermal effects due to parametric changes are also presented in this thesis. Universiti Sains Malaysia 2005-03-01 Monograph NonPeerReviewed application/pdf en http://eprints.usm.my/58167/1/Biomems%20Thermal%20Effects%20Analysis%20Of%20DNA%20Cocktail%20Solution%20%28DCS%29%20In%20A%20Microfluidic%20Channel.pdf Khor, Hee Huat (2005) Biomems: Thermal Effects Analysis Of DNA Cocktail Solution (DCS) In A Microfluidic Channel. Project Report. Universiti Sains Malaysia, Pusat Pengajian Kejuruteraan Mekanikal. (Submitted) |
| spellingShingle | T Technology TJ Mechanical engineering and machinery Khor, Hee Huat Biomems: Thermal Effects Analysis Of DNA Cocktail Solution (DCS) In A Microfluidic Channel |
| title | Biomems: Thermal Effects Analysis Of DNA Cocktail Solution (DCS) In A Microfluidic Channel |
| title_full | Biomems: Thermal Effects Analysis Of DNA Cocktail Solution (DCS) In A Microfluidic Channel |
| title_fullStr | Biomems: Thermal Effects Analysis Of DNA Cocktail Solution (DCS) In A Microfluidic Channel |
| title_full_unstemmed | Biomems: Thermal Effects Analysis Of DNA Cocktail Solution (DCS) In A Microfluidic Channel |
| title_short | Biomems: Thermal Effects Analysis Of DNA Cocktail Solution (DCS) In A Microfluidic Channel |
| title_sort | biomems: thermal effects analysis of dna cocktail solution (dcs) in a microfluidic channel |
| topic | T Technology TJ Mechanical engineering and machinery |
| url | http://eprints.usm.my/58167/ http://eprints.usm.my/58167/1/Biomems%20Thermal%20Effects%20Analysis%20Of%20DNA%20Cocktail%20Solution%20%28DCS%29%20In%20A%20Microfluidic%20Channel.pdf |