Effects of dietary vitamin C and E supplementation on exercise-induced muscle damage among young weightlifters

Dietary supplements vitamin C and E have shown to reduce oxidative stress and muscle damage markers following the exercise. Therefore, it has been hypothesized that markers of oxidative stress and muscle damage induced weightlifting training could be decreased by supplementing subjects with vitamin...

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Main Author: Mohammed, Sawash M.
Format: Thesis
Language:English
Published: 2011
Subjects:
Online Access:http://eprints.usm.my/57437/
http://eprints.usm.my/57437/1/SAWASH%20M%20MOHAMMED%20-%20e.pdf
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author Mohammed, Sawash M.
author_facet Mohammed, Sawash M.
author_sort Mohammed, Sawash M.
building USM Institutional Repository
collection Online Access
description Dietary supplements vitamin C and E have shown to reduce oxidative stress and muscle damage markers following the exercise. Therefore, it has been hypothesized that markers of oxidative stress and muscle damage induced weightlifting training could be decreased by supplementing subjects with vitamin C and E. 32 trained weightlifters recruited and randomly assigned into two groups: Supplement group were given 500 mg of vitamin C and 400 IU of vitamin E per day, while placebo group given maltodextrine, zero calorie per day for 6 weeks. Serum creatine kinase (CK), lactate dehydrogenase (LDH), aspartate aminotransferase (AST), Alanine transaminase (ALT), creatinine and urea. Urinary TBARS and Circumferences of mid arm, mid-thigh and calf were measured before and after supplementation. All data were expressed as median and interquartile range. All the statistical significance was accepted at p < 0.05. There was no significant effect (p>0.05) of vitamin supplementation on LDH, CK and urinary TBARS between two groups. There was no significant effect of vitamin C and E supplements on hepatic enzymes AST and ALT; there was statistically significant difference (p<0.05) in renal enzymes, creatinine and urea, but no effect happened and the values were within the normal reference value. These data indicate that vitamin C and E were not effective in ameliorating markers of muscle damage and oxidative stress induced weightlifting training in trained individuals. Moreover, intake of vitamin C and E for 6 weeks showed no toxic effects on hepatic and renal function.
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spelling usm-574372023-03-22T02:01:38Z http://eprints.usm.my/57437/ Effects of dietary vitamin C and E supplementation on exercise-induced muscle damage among young weightlifters Mohammed, Sawash M. GV Recreation Leisure RM300-666 Drugs and their actions Dietary supplements vitamin C and E have shown to reduce oxidative stress and muscle damage markers following the exercise. Therefore, it has been hypothesized that markers of oxidative stress and muscle damage induced weightlifting training could be decreased by supplementing subjects with vitamin C and E. 32 trained weightlifters recruited and randomly assigned into two groups: Supplement group were given 500 mg of vitamin C and 400 IU of vitamin E per day, while placebo group given maltodextrine, zero calorie per day for 6 weeks. Serum creatine kinase (CK), lactate dehydrogenase (LDH), aspartate aminotransferase (AST), Alanine transaminase (ALT), creatinine and urea. Urinary TBARS and Circumferences of mid arm, mid-thigh and calf were measured before and after supplementation. All data were expressed as median and interquartile range. All the statistical significance was accepted at p < 0.05. There was no significant effect (p>0.05) of vitamin supplementation on LDH, CK and urinary TBARS between two groups. There was no significant effect of vitamin C and E supplements on hepatic enzymes AST and ALT; there was statistically significant difference (p<0.05) in renal enzymes, creatinine and urea, but no effect happened and the values were within the normal reference value. These data indicate that vitamin C and E were not effective in ameliorating markers of muscle damage and oxidative stress induced weightlifting training in trained individuals. Moreover, intake of vitamin C and E for 6 weeks showed no toxic effects on hepatic and renal function. 2011-05 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/57437/1/SAWASH%20M%20MOHAMMED%20-%20e.pdf Mohammed, Sawash M. (2011) Effects of dietary vitamin C and E supplementation on exercise-induced muscle damage among young weightlifters. Masters thesis, Universiti Sains Malaysia.
spellingShingle GV Recreation Leisure
RM300-666 Drugs and their actions
Mohammed, Sawash M.
Effects of dietary vitamin C and E supplementation on exercise-induced muscle damage among young weightlifters
title Effects of dietary vitamin C and E supplementation on exercise-induced muscle damage among young weightlifters
title_full Effects of dietary vitamin C and E supplementation on exercise-induced muscle damage among young weightlifters
title_fullStr Effects of dietary vitamin C and E supplementation on exercise-induced muscle damage among young weightlifters
title_full_unstemmed Effects of dietary vitamin C and E supplementation on exercise-induced muscle damage among young weightlifters
title_short Effects of dietary vitamin C and E supplementation on exercise-induced muscle damage among young weightlifters
title_sort effects of dietary vitamin c and e supplementation on exercise-induced muscle damage among young weightlifters
topic GV Recreation Leisure
RM300-666 Drugs and their actions
url http://eprints.usm.my/57437/
http://eprints.usm.my/57437/1/SAWASH%20M%20MOHAMMED%20-%20e.pdf