Neuronal activation in patients with mild and moderate traumatic brain injury during working memory tasks
Background and Objective Cognitive impairment in patients following TBI is a significant cause of morbidity both to patients and their families. Memory impairment is one of the most common complaint patients and their families have as it impairs patients’ daily function. Current neuroimaging mod...
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| Format: | Thesis |
| Language: | English |
| Published: |
2020
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| Subjects: | |
| Online Access: | http://eprints.usm.my/57316/ http://eprints.usm.my/57316/1/DR%20DIANA%20NOMA%20BINTI%20FITZROL-24%20pages.pdf |
| _version_ | 1848883590866141184 |
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| author | Fitzrol, Diana Noma |
| author_facet | Fitzrol, Diana Noma |
| author_sort | Fitzrol, Diana Noma |
| building | USM Institutional Repository |
| collection | Online Access |
| description | Background and Objective
Cognitive impairment in patients following TBI is a significant cause of morbidity
both to patients and their families. Memory impairment is one of the most common
complaint patients and their families have as it impairs patients’ daily function. Current
neuroimaging modalities allows us to study the neuronal activation relevant to working
memory in patients.
Methods
Patients who sustained mTBI/ modTBI, between the age of 18 to 65 years old and
managed in Hospital Universiti Sains Malaysia were recruited into the study. These patients
and a control group underwent fMRI scanning where they concurrently performed n-back
tasks of 4 different memory loads. These fMRI scans were performed at 6 to 10 weeks postinjury
and at 6 months post-injury. These cohort of subjects also had neuropsychology
assessments performed at the same two time period as the fMRI.
Results |
| first_indexed | 2025-11-15T18:53:14Z |
| format | Thesis |
| id | usm-57316 |
| institution | Universiti Sains Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T18:53:14Z |
| publishDate | 2020 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | usm-573162023-03-14T09:09:43Z http://eprints.usm.my/57316/ Neuronal activation in patients with mild and moderate traumatic brain injury during working memory tasks Fitzrol, Diana Noma R Medicine RC31-1245 Internal medicine Background and Objective Cognitive impairment in patients following TBI is a significant cause of morbidity both to patients and their families. Memory impairment is one of the most common complaint patients and their families have as it impairs patients’ daily function. Current neuroimaging modalities allows us to study the neuronal activation relevant to working memory in patients. Methods Patients who sustained mTBI/ modTBI, between the age of 18 to 65 years old and managed in Hospital Universiti Sains Malaysia were recruited into the study. These patients and a control group underwent fMRI scanning where they concurrently performed n-back tasks of 4 different memory loads. These fMRI scans were performed at 6 to 10 weeks postinjury and at 6 months post-injury. These cohort of subjects also had neuropsychology assessments performed at the same two time period as the fMRI. Results 2020 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/57316/1/DR%20DIANA%20NOMA%20BINTI%20FITZROL-24%20pages.pdf Fitzrol, Diana Noma (2020) Neuronal activation in patients with mild and moderate traumatic brain injury during working memory tasks. Masters thesis, Pusat Pengajian Sains Perubatan. |
| spellingShingle | R Medicine RC31-1245 Internal medicine Fitzrol, Diana Noma Neuronal activation in patients with mild and moderate traumatic brain injury during working memory tasks |
| title | Neuronal activation in patients with mild and moderate traumatic brain injury during working memory tasks |
| title_full | Neuronal activation in patients with mild and moderate traumatic brain injury during working memory tasks |
| title_fullStr | Neuronal activation in patients with mild and moderate traumatic brain injury during working memory tasks |
| title_full_unstemmed | Neuronal activation in patients with mild and moderate traumatic brain injury during working memory tasks |
| title_short | Neuronal activation in patients with mild and moderate traumatic brain injury during working memory tasks |
| title_sort | neuronal activation in patients with mild and moderate traumatic brain injury during working memory tasks |
| topic | R Medicine RC31-1245 Internal medicine |
| url | http://eprints.usm.my/57316/ http://eprints.usm.my/57316/1/DR%20DIANA%20NOMA%20BINTI%20FITZROL-24%20pages.pdf |