The Effects Of Pioglitazone And MK886
ON THE Mrna EXPRESSION OF PPAR-alpha,
PPAR-gamma And Its Associated GENES,
Cell Death And Migration In MDA-MB-
231 Cancer Cells

QR Code

The Effects Of Pioglitazone And MK886 ON THE Mrna EXPRESSION OF PPAR-alpha, PPAR-gamma And Its Associated GENES, Cell Death And Migration In MDA-MB- 231 Cancer Cells

Pioglitazone (PGZ) is a prescription drug used in the treatment of diabetes mellitus type II. It is a well-known synthetic agonist for PP AR, and being studied extensively by our research group as a target drug for the treatment of ER-negative breast cancer. The ER-negative breast cancer is more...

Full description

Bibliographic Details
Main Author:	Nadarajan, Kalpanah
Format:	Thesis
Language:	English
Published:	2015
Subjects:	R Medicine RC254-282 Neoplasms. Tumors. Oncology (including Cancer)
Online Access:	http://eprints.usm.my/56796/ http://eprints.usm.my/56796/1/00001792017%20Kalpanah%20a.p%20Nadarajan.pdf

Similar Items

The expression of PPARS gamma in the cervical cancer line, hela and the effects of specific PPAR ligand on cell growth
by: Yaacob, Nik Soriani
Published: (2013)

The effects of valproic acid on navi.5 gene expression in mda-mb- 231 cells
by: Kandivan, Hemalatha
Published: (2016)

Methanolic extract of Abrus precatorius promotes breast cancer MDA-MB-231 cell death by inducing cell cycle arrest at G0/G1 and upregulating Bax
by: Ismail, Norzila, et al.
Published: (2019)

Methanolic extract of Abrus precatorius promotes breast cancer MDA-MB-231 cell death by inducing cell cycle arrest at G0/G1 and upregulating Bax
by: Ibrahim, Wan Suriyani Wan
Published: (2019)

Effects of knocking-down HIF-la on migration in human breast cancer cell MDA-MB-231
by: Rashid, Nur Sabrina Abd
Published: (2015)

Anticancer Studies Of Ximenia Americana And Catharanthus Roseus In Human Breast Cancer Cell Lines Mcf7 And Mda-Mb-231
by: Eltahir, Nagla Mustafa Eltayeb
Published: (2021)

The role of strobilanthes crispus active fraction (f3) on glucose metabolism of MDA-MB-231 breast cancer cell line
by: Muhammad, Siti Nur Hasyila
Published: (2023)

Anticancer effect of artonin E and chaplashin from artocarpus species on breast cancer cells, MDA-MB-231 and MCF-7
by: Ling, Choo Yen
Published: (2013)

Elucidation Of The Mechanism Involved In The Proliferation And Migration Activity Of Cyperus Esculentus Lativum In Mda-Mb-231 And Mcf7 Breast Cancer Cell Lines
by: Seyram, Elom Achoribo
Published: (2019)

mRNA expression of Somatostatin receptors 1-5 in MCF7 and MDA-MB231 breast cancer cells
by: Mahmoud, Alkhansa, et al.
Published: (2021)

Citral induced apoptosis in MDA-MB-231 spheroid cells
by: Rosli, Rozita, et al.
Published: (2018)

The expression of ppars gamma in the cervical cancer line, bela and the effects of specific PPAR ligand on cell growth
by: Yaacob, Nik Soriani
Published: (2013)

Effects Of Chrysin On The mRNA Expression Of Peroxisome Proliferator-Activated Receptor Alpha (PPARα) And Cyp Genes, Cell Cycle And Cell Migration In Colorectal Cancer Hct-116 Cells
by: Khor, Chin Yin
Published: (2020)

Evaluation of the PPAR-γ agonist pioglitazone in mild asthma: a double-blind randomized controlled trial
by: Leroyer, Christophe, et al.
Published: (2016)

Evaluation of the PPAR-γ agonist pioglitazone in mild asthma: a double-blind randomized controlled trial
by: Anderson, J.R., et al.
Published: (2016)

Effects of knocking-down HIF-la (siRNA) on vgsc expression in the aggressive human breast cancer cells (MDA-MB-231)
by: Hussin, Mohd Zaki
Published: (2015)

Anticancer-immune response towards breast cancer cell lines MDA-MB-231 and teratogenic assessment of Pereskia bleo leaves
by: Dalfi, Taif Kareem Khalaf
Published: (2024)

Effects of silencing dishevelled 1, 2 and 3 mRNA expression on MDA-MB-231 cell migration and invasion using siRNAs
by: Khoo, Samuel Leon Juan
Published: (2015)

Tindak balas antikanser-imun terhadap sel kanser payudara mda-mb-231 dan penilaian teratogenik daun pereskia bleo
by: Dalfi, Taif Kareem Khalf
Published: (2024)

Effect of linoleic acid of Nigella sativa on MDA-MB-231 human breast cancer cells.
by: G. K., Hasanzadeh, et al.
Published: (2011)

Immune regulation of autoimmune diabetes: the role of regulatory t(t-reg) cells & ppar gamma
by: Nor, Norazmi Mohd
Published: (2015)

Anti cancer activity of plant extracts on MDA-MB231
by: Yussoff, Seri Wahyuni
Published: (2015)

Ampelopsin E reduces the invasiveness of the triple negative breast cancer cell line, MDA-MB-231
by: Tieng, Francis Yew Fu, et al.
Published: (2019)

The effects of 2-methoxy-1,4-naphthoquinone (mnq) on glucose metabolism of mda-mb-231 cells
by: Daud, Syukriyah Mat
Published: (2020)

The role of peroxisome proliferator activated receptor alpha (PPARα) in the effect of piroxicam on colon cancer
by: McCartney, Karen M.
Published: (2015)

Flavokawain B Induced cytotoxicity in Two Breast Cancer Cell Lines, MCF-7 and MDA-MB231 and Inhibited the Metastatic Potential of MDA-MB231 via the Regulation of Several Tyrosine Kinases In vitro
by: Nadiah, Abu, et al.
Published: (2016)

Flavokawain B induced cytotoxicity in two breast cancer cell lines, MCF-7 and MDA-MB231 and inhibited the metastatic potential of MDA-MB231 via the regulation of several tyrosine kinases in vitro
by: Abu, Nadiah, et al.
Published: (2016)

The expression of peroxisome proliferator-activated receptor (ppar1 and ppar2) in naive and memory cd4+ t lymphocytes
by: Mohamed, Rafeezul
Published: (2006)

Anticancer activity of thymoquinone in breast cancer cells: Possible involvement of PPAR-γ pathway
by: Woo, C., et al.
Published: (2011)

Design, synthesis of flavokawain b derivative and their cytotoxic effects on MCF-7 and MDA-MB-231 cell lines
by: Addila, Abu Bakar
Published: (2018)

Oncolytic Effect Of Newcastle Disease Virus On The Mcf-7 And Mda-Mb-231 Breast Cancer Cell Lines
by: Meyyappan, Narayani
Published: (2003)

Curcumin from turmeric (Curcuma longa) induced apoptosis in human mammary carcinoma cells (MDA-MB-231)
by: Saiful Yazan, Latifah, et al.
Published: (2006)

Effects of ampelopsin E towards the invasiveness of triple negative breast cancer cell line, MDA-MB-231
by: Tieng, Francis Yew Fu
Published: (2019)

The molecular mechanism of the anticancer effect of Artonin E in MDA-MB 231 triple negative breast cancer cells
by: Etti, Imaobong Christopher, et al.
Published: (2017)

Treatment of MCF-7 and MDA-MB-231 human breast cancer cell lines with erythropoietin, doxorubicin and their combination
by: Radwan, Esam M.
Published: (2015)

Establishment of hypoxia-induced invadopodia model and phenotype characterisation of MDA-MB- 231 breast cancer cell line
by: Hamad, Hamad Hamad Ali
Published: (2019)

Expression of the transcription factor, PPAR in human monocytes
by: Jen, Ku Sheau
Published: (2004)

Investigating the effect of andrographolide on HMGCR protein expression in MDA-MB-231
by: Abdulateef, Al-Hakam Ahmed
Published: (2019)

Inhibition of adult liver progenitor (oval) cell growth and viability by an agonist of the peroxisome proliferator activated receptor (PPAR) family member gamma, but not alpha or delta
by: Knight, B., et al.
Published: (2005)

Assessment of cytotoxicity potency of paclitaxel in combination with Clinacanthus Nutans extracts on human MDA-MB-231 breast cancer cells
by: Nur Hasnieza Mohd Rosli,, et al.
Published: (2018)