Study of computed tomography perfusion In traumatic brain contusion

Background: Brain ischaemia and infarction are the leading factors in morbidity and mortality of traumatic brain injury. TI1is study aimed to determine the perfusion status of pericontusional hypodense areas in traumatic cerebral contusion Method: Ten patients involved in motor vehicle accidents...

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Main Author: Karim, Ahmad Helmy Abdul
Format: Monograph
Language:English
Published: Pusat Pengajian Sains Perubatan, Universiti Sains Malaysia 2013
Subjects:
Online Access:http://eprints.usm.my/54975/
http://eprints.usm.my/54975/1/DR%20AHMAD%20HELMY%20ABDUL%20KARIM-Eprints.pdf
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author Karim, Ahmad Helmy Abdul
author_facet Karim, Ahmad Helmy Abdul
author_sort Karim, Ahmad Helmy Abdul
building USM Institutional Repository
collection Online Access
description Background: Brain ischaemia and infarction are the leading factors in morbidity and mortality of traumatic brain injury. TI1is study aimed to determine the perfusion status of pericontusional hypodense areas in traumatic cerebral contusion Method: Ten patients involved in motor vehicle accidents were enrolled in this study, and contusions were diagnosed from plain computed tomography scans of the brain. Subsequent computed tomography perfusion (en>) was performed to analyse the perfusion ofpericontusional hypodense areas, whicll were divided into 4 regions of interest (ROI). Results: Most ischaemic perfusion was found in ROI 6 (affecting 60% of patients), although the mean of the perfusion parameters were normal. A significant positive correlation was fonnd between the perfusion status in the pericontusional area nearest to the skull vault (ROI 3) and its distance/thickness to the skull vault (r = 0.698, P = 0.025). Two adjacent pericontusional hypodense areas (ROI 4 and ROI 5) showed a significant positive correlation with eacll other (r = 0.667, P = 0.035) in terms of perfusion status. The presence of a hypodense pericontusional area is suggestive of oedema and perfusion disturbances. Conclusion: en> is a useful, fast, and appropriate method in evaluating perfusion of pericontusional hypodensity area that may help the treating physician to provide an appropriate treatment to the patient.
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spelling usm-549752022-09-28T07:36:42Z http://eprints.usm.my/54975/ Study of computed tomography perfusion In traumatic brain contusion Karim, Ahmad Helmy Abdul R Medicine Background: Brain ischaemia and infarction are the leading factors in morbidity and mortality of traumatic brain injury. TI1is study aimed to determine the perfusion status of pericontusional hypodense areas in traumatic cerebral contusion Method: Ten patients involved in motor vehicle accidents were enrolled in this study, and contusions were diagnosed from plain computed tomography scans of the brain. Subsequent computed tomography perfusion (en>) was performed to analyse the perfusion ofpericontusional hypodense areas, whicll were divided into 4 regions of interest (ROI). Results: Most ischaemic perfusion was found in ROI 6 (affecting 60% of patients), although the mean of the perfusion parameters were normal. A significant positive correlation was fonnd between the perfusion status in the pericontusional area nearest to the skull vault (ROI 3) and its distance/thickness to the skull vault (r = 0.698, P = 0.025). Two adjacent pericontusional hypodense areas (ROI 4 and ROI 5) showed a significant positive correlation with eacll other (r = 0.667, P = 0.035) in terms of perfusion status. The presence of a hypodense pericontusional area is suggestive of oedema and perfusion disturbances. Conclusion: en> is a useful, fast, and appropriate method in evaluating perfusion of pericontusional hypodensity area that may help the treating physician to provide an appropriate treatment to the patient. Pusat Pengajian Sains Perubatan, Universiti Sains Malaysia 2013 Monograph NonPeerReviewed application/pdf en http://eprints.usm.my/54975/1/DR%20AHMAD%20HELMY%20ABDUL%20KARIM-Eprints.pdf Karim, Ahmad Helmy Abdul (2013) Study of computed tomography perfusion In traumatic brain contusion. Other. Pusat Pengajian Sains Perubatan, Universiti Sains Malaysia.
spellingShingle R Medicine
Karim, Ahmad Helmy Abdul
Study of computed tomography perfusion In traumatic brain contusion
title Study of computed tomography perfusion In traumatic brain contusion
title_full Study of computed tomography perfusion In traumatic brain contusion
title_fullStr Study of computed tomography perfusion In traumatic brain contusion
title_full_unstemmed Study of computed tomography perfusion In traumatic brain contusion
title_short Study of computed tomography perfusion In traumatic brain contusion
title_sort study of computed tomography perfusion in traumatic brain contusion
topic R Medicine
url http://eprints.usm.my/54975/
http://eprints.usm.my/54975/1/DR%20AHMAD%20HELMY%20ABDUL%20KARIM-Eprints.pdf