Antimicrobial effect of commonly used herbs in Malaysia

The rhizome of Curcuma xanthorrhiza Roxb. (Zingiberaceae family, commonly known as temulawak) is a type of herb that has been used in therapeutics for hundreds of years. However, little attention has been paid to its effects on oral bacteria. The aims of this study were to determine the antimicro...

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Main Author: Sarliza Yasmin, Sanusi
Format: Monograph
Language:English
Published: Pusat Pengajian Sains Perubatan 2013
Subjects:
Online Access:http://eprints.usm.my/54833/
http://eprints.usm.my/54833/1/DR.%20SARLIZA%20YASMIN%20SANUSI%20-%20e.pdf
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author Sarliza Yasmin, Sanusi
author_facet Sarliza Yasmin, Sanusi
author_sort Sarliza Yasmin, Sanusi
building USM Institutional Repository
collection Online Access
description The rhizome of Curcuma xanthorrhiza Roxb. (Zingiberaceae family, commonly known as temulawak) is a type of herb that has been used in therapeutics for hundreds of years. However, little attention has been paid to its effects on oral bacteria. The aims of this study were to determine the antimicrobial effects and the minimal inhibitory concentration (MIC) of Rhizoma Curcuma Xanthorrizae against oral bacteria. The former was determined using agar well diffusion method whereas the latter was determined using broth dilution (Tripticase Soy Broth) method. Nine types of oral bacteria namely Streptococcus mutans, Streptococcus sanguis, Streptococcus ora/is, Streptococcus sobrinus, Staphylococcus aureus, Lactobacillus Salivarius, Enterococcus faecalis, Pseudomonas aerugirosa and Eschericia coli were used in this study. Results showed that water extract of Rhizome Curcuma Xanthorrhizae did not exhibit any antibacterial effects against oral bacteria. Temulawak ethanol extract demonstrated antibacterial effects against Streptococcus mutans, Streptococcus sanguis, Streptococcus ora/is, Staphylococcus aureus and Enterococcus faecalis. The MIC value was lg/ml. The MIC value could be utilised as baseline data for contrivance of potential antimicrobial agents such as drugs or mouthwash. Further research should be carried out to deduce the active components of this plant that are responsible for its antibacterial activities.
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institution Universiti Sains Malaysia
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language English
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spelling usm-548332022-09-20T07:49:36Z http://eprints.usm.my/54833/ Antimicrobial effect of commonly used herbs in Malaysia Sarliza Yasmin, Sanusi R Medicine (General) The rhizome of Curcuma xanthorrhiza Roxb. (Zingiberaceae family, commonly known as temulawak) is a type of herb that has been used in therapeutics for hundreds of years. However, little attention has been paid to its effects on oral bacteria. The aims of this study were to determine the antimicrobial effects and the minimal inhibitory concentration (MIC) of Rhizoma Curcuma Xanthorrizae against oral bacteria. The former was determined using agar well diffusion method whereas the latter was determined using broth dilution (Tripticase Soy Broth) method. Nine types of oral bacteria namely Streptococcus mutans, Streptococcus sanguis, Streptococcus ora/is, Streptococcus sobrinus, Staphylococcus aureus, Lactobacillus Salivarius, Enterococcus faecalis, Pseudomonas aerugirosa and Eschericia coli were used in this study. Results showed that water extract of Rhizome Curcuma Xanthorrhizae did not exhibit any antibacterial effects against oral bacteria. Temulawak ethanol extract demonstrated antibacterial effects against Streptococcus mutans, Streptococcus sanguis, Streptococcus ora/is, Staphylococcus aureus and Enterococcus faecalis. The MIC value was lg/ml. The MIC value could be utilised as baseline data for contrivance of potential antimicrobial agents such as drugs or mouthwash. Further research should be carried out to deduce the active components of this plant that are responsible for its antibacterial activities. Pusat Pengajian Sains Perubatan 2013 Monograph NonPeerReviewed application/pdf en http://eprints.usm.my/54833/1/DR.%20SARLIZA%20YASMIN%20SANUSI%20-%20e.pdf Sarliza Yasmin, Sanusi (2013) Antimicrobial effect of commonly used herbs in Malaysia. Other. Pusat Pengajian Sains Perubatan. (Submitted)
spellingShingle R Medicine (General)
Sarliza Yasmin, Sanusi
Antimicrobial effect of commonly used herbs in Malaysia
title Antimicrobial effect of commonly used herbs in Malaysia
title_full Antimicrobial effect of commonly used herbs in Malaysia
title_fullStr Antimicrobial effect of commonly used herbs in Malaysia
title_full_unstemmed Antimicrobial effect of commonly used herbs in Malaysia
title_short Antimicrobial effect of commonly used herbs in Malaysia
title_sort antimicrobial effect of commonly used herbs in malaysia
topic R Medicine (General)
url http://eprints.usm.my/54833/
http://eprints.usm.my/54833/1/DR.%20SARLIZA%20YASMIN%20SANUSI%20-%20e.pdf