A preliminary study: effect of local honey on spermatogenesis in rats

The aim of this study was 10 evaluate the effect of different doses of Malaysian honey on male reproductive parameters in adult rats. Thirty-two healthy adult male Sprague-Dawley rats were randomly divided into 4 groups (8 rats per group). Group 1 (control group) was given 0.5 ml of distilled wate...

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Main Author: Mohamed, Mahaneem
Format: Monograph
Language:English
Published: Pusat Pengajian Sains Perubatan, Universiti Sains Malaysia 2010
Subjects:
Online Access:http://eprints.usm.my/54535/
http://eprints.usm.my/54535/1/Mahaneem%20Mohamed-Eprints.pdf
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author Mohamed, Mahaneem
author_facet Mohamed, Mahaneem
author_sort Mohamed, Mahaneem
building USM Institutional Repository
collection Online Access
description The aim of this study was 10 evaluate the effect of different doses of Malaysian honey on male reproductive parameters in adult rats. Thirty-two healthy adult male Sprague-Dawley rats were randomly divided into 4 groups (8 rats per group). Group 1 (control group) was given 0.5 ml of distilled water. Groups 2, 3 and 4 were given 0.2, 1.2 and 2.4 g kg·' body weight of honey, respectively. The rats were treated orally by gavage once daily for 4 weeks. Honey did not significantlr alter body and male reproductive organs weights. The rats in Group 3 which received honey at 1.2 g kg· had significantly higher epididymal sperm count than those in Groups 1, 2 and 4. No significant differences were found for the percentage of abnormal sperm, elongated spermatid count, reproductive hormonal levels as well as the histology of the testis among the groups. In conclusion, Malaysian honey at a dose of 1.2 g kg·' daily significantly increased epididymal sperm count without affecting spermatid count and reproductive hormones. These findings might suggest that oral administration of honey at this dose for 4 weeks may enhance spermiogenesis in adult rats .
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language English
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spelling usm-545352022-09-07T07:40:13Z http://eprints.usm.my/54535/ A preliminary study: effect of local honey on spermatogenesis in rats Mohamed, Mahaneem R Medicine The aim of this study was 10 evaluate the effect of different doses of Malaysian honey on male reproductive parameters in adult rats. Thirty-two healthy adult male Sprague-Dawley rats were randomly divided into 4 groups (8 rats per group). Group 1 (control group) was given 0.5 ml of distilled water. Groups 2, 3 and 4 were given 0.2, 1.2 and 2.4 g kg·' body weight of honey, respectively. The rats were treated orally by gavage once daily for 4 weeks. Honey did not significantlr alter body and male reproductive organs weights. The rats in Group 3 which received honey at 1.2 g kg· had significantly higher epididymal sperm count than those in Groups 1, 2 and 4. No significant differences were found for the percentage of abnormal sperm, elongated spermatid count, reproductive hormonal levels as well as the histology of the testis among the groups. In conclusion, Malaysian honey at a dose of 1.2 g kg·' daily significantly increased epididymal sperm count without affecting spermatid count and reproductive hormones. These findings might suggest that oral administration of honey at this dose for 4 weeks may enhance spermiogenesis in adult rats . Pusat Pengajian Sains Perubatan, Universiti Sains Malaysia 2010 Monograph NonPeerReviewed application/pdf en http://eprints.usm.my/54535/1/Mahaneem%20Mohamed-Eprints.pdf Mohamed, Mahaneem (2010) A preliminary study: effect of local honey on spermatogenesis in rats. Other. Pusat Pengajian Sains Perubatan, Universiti Sains Malaysia.
spellingShingle R Medicine
Mohamed, Mahaneem
A preliminary study: effect of local honey on spermatogenesis in rats
title A preliminary study: effect of local honey on spermatogenesis in rats
title_full A preliminary study: effect of local honey on spermatogenesis in rats
title_fullStr A preliminary study: effect of local honey on spermatogenesis in rats
title_full_unstemmed A preliminary study: effect of local honey on spermatogenesis in rats
title_short A preliminary study: effect of local honey on spermatogenesis in rats
title_sort preliminary study: effect of local honey on spermatogenesis in rats
topic R Medicine
url http://eprints.usm.my/54535/
http://eprints.usm.my/54535/1/Mahaneem%20Mohamed-Eprints.pdf