Behavioural, Biochemical, Proteomics Studies And Replacement Therapy Of Morphine And Mitragynine Withdrawal Rat Models
The current study was designed to test the ability of mitragynine to attenuate behavioural signs of morphine-withdrawal in a rat model in comparison to methadone and buprenorphine. A six-day treatment with escalating dose of morphine (10-50 mg/kg, i.p.) induced profound withdrawal signs for 16 days.
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| Format: | Thesis |
| Language: | English |
| Published: |
2021
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| Online Access: | http://eprints.usm.my/53633/ http://eprints.usm.my/53633/1/RAHIMAH%20BINTI%20HASSAN%20-%20TESIS.pdf%20cut.pdf |
| _version_ | 1848882583651221504 |
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| author | Hassan, Rahimah |
| author_facet | Hassan, Rahimah |
| author_sort | Hassan, Rahimah |
| building | USM Institutional Repository |
| collection | Online Access |
| description | The current study was designed to test the ability of mitragynine to attenuate behavioural signs of morphine-withdrawal in a rat model in comparison to methadone and buprenorphine. A six-day treatment with escalating dose of morphine (10-50 mg/kg, i.p.) induced profound withdrawal signs for 16 days. |
| first_indexed | 2025-11-15T18:37:14Z |
| format | Thesis |
| id | usm-53633 |
| institution | Universiti Sains Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T18:37:14Z |
| publishDate | 2021 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | usm-536332022-07-27T07:44:53Z http://eprints.usm.my/53633/ Behavioural, Biochemical, Proteomics Studies And Replacement Therapy Of Morphine And Mitragynine Withdrawal Rat Models Hassan, Rahimah RM300-666 Drugs and their actions The current study was designed to test the ability of mitragynine to attenuate behavioural signs of morphine-withdrawal in a rat model in comparison to methadone and buprenorphine. A six-day treatment with escalating dose of morphine (10-50 mg/kg, i.p.) induced profound withdrawal signs for 16 days. 2021-01 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/53633/1/RAHIMAH%20BINTI%20HASSAN%20-%20TESIS.pdf%20cut.pdf Hassan, Rahimah (2021) Behavioural, Biochemical, Proteomics Studies And Replacement Therapy Of Morphine And Mitragynine Withdrawal Rat Models. PhD thesis, Universiti Sains Malaysia. |
| spellingShingle | RM300-666 Drugs and their actions Hassan, Rahimah Behavioural, Biochemical, Proteomics Studies And Replacement Therapy Of Morphine And Mitragynine Withdrawal Rat Models |
| title | Behavioural, Biochemical, Proteomics Studies And Replacement Therapy Of Morphine And Mitragynine Withdrawal Rat Models |
| title_full | Behavioural, Biochemical, Proteomics Studies And Replacement Therapy Of Morphine And Mitragynine Withdrawal Rat Models |
| title_fullStr | Behavioural, Biochemical, Proteomics Studies And Replacement Therapy Of Morphine And Mitragynine Withdrawal Rat Models |
| title_full_unstemmed | Behavioural, Biochemical, Proteomics Studies And Replacement Therapy Of Morphine And Mitragynine Withdrawal Rat Models |
| title_short | Behavioural, Biochemical, Proteomics Studies And Replacement Therapy Of Morphine And Mitragynine Withdrawal Rat Models |
| title_sort | behavioural, biochemical, proteomics studies and replacement therapy of morphine and mitragynine withdrawal rat models |
| topic | RM300-666 Drugs and their actions |
| url | http://eprints.usm.my/53633/ http://eprints.usm.my/53633/1/RAHIMAH%20BINTI%20HASSAN%20-%20TESIS.pdf%20cut.pdf |