A study on antiproliferative activity of methanolic extract of Nephelium lappaceum peel towards selected cancer cell lines

Nephelium lappaceum which belongs to family Sapindaceae is subtropical and tropical native fruit of the Southeast Asia but unknown in the United States (Ong et al., 1998). Nephelium lappaceum is known as rambutan in Malaysia where the fruit is generally consumed fresh and industrially processed to...

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Main Author: Sul'ain, Mohd Dasuki
Format: Monograph
Language:English
Published: Pusat Pengajian Sains Perubatan, Universiti Sains Malaysia 2011
Subjects:
Online Access:http://eprints.usm.my/53444/
http://eprints.usm.my/53444/1/DR%20MOHD%20DASUKI%20SUL%27AIN-Eprints.pdf
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author Sul'ain, Mohd Dasuki
author_facet Sul'ain, Mohd Dasuki
author_sort Sul'ain, Mohd Dasuki
building USM Institutional Repository
collection Online Access
description Nephelium lappaceum which belongs to family Sapindaceae is subtropical and tropical native fruit of the Southeast Asia but unknown in the United States (Ong et al., 1998). Nephelium lappaceum is known as rambutan in Malaysia where the fruit is generally consumed fresh and industrially processed to juices, jams and jellies. However, the seeds and peels of Nephe/ium /appaceum are often treated as a waste. Some phytochemical constituent such as geraniin (Palanisamy et al., 2010), ascorbic acid and vitamin c (Wall, 2006) and volatile compounds (Ong et al., 1998) of Nephelium lappaceum had been isolated from the fruits and peels. Studies on Nephe/ium lappaceum showed it to pose some therapeutic activities such as antioxidant (Palanisamy et al., 2008), antibacterial (Thitilertdecha et a!., 2008), antivirus (Nawawi, 1999) and anti-hyperglycemic (Palanisamy et al., 2010). In this study, Nephe/ium lappaceum was extracted using a different organic solvents and were tested for antiproliferative effect on several cancer cell lines using methylene blue assay. The purpose of this study was to determine the antiproliferative activity of organic extracts of Nephelium lappaceum peels on selected cancer cell lines.
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institution Universiti Sains Malaysia
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language English
last_indexed 2025-11-15T18:36:23Z
publishDate 2011
publisher Pusat Pengajian Sains Perubatan, Universiti Sains Malaysia
recordtype eprints
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spelling usm-534442022-07-18T08:26:19Z http://eprints.usm.my/53444/ A study on antiproliferative activity of methanolic extract of Nephelium lappaceum peel towards selected cancer cell lines Sul'ain, Mohd Dasuki R Medicine Nephelium lappaceum which belongs to family Sapindaceae is subtropical and tropical native fruit of the Southeast Asia but unknown in the United States (Ong et al., 1998). Nephelium lappaceum is known as rambutan in Malaysia where the fruit is generally consumed fresh and industrially processed to juices, jams and jellies. However, the seeds and peels of Nephe/ium /appaceum are often treated as a waste. Some phytochemical constituent such as geraniin (Palanisamy et al., 2010), ascorbic acid and vitamin c (Wall, 2006) and volatile compounds (Ong et al., 1998) of Nephelium lappaceum had been isolated from the fruits and peels. Studies on Nephe/ium lappaceum showed it to pose some therapeutic activities such as antioxidant (Palanisamy et al., 2008), antibacterial (Thitilertdecha et a!., 2008), antivirus (Nawawi, 1999) and anti-hyperglycemic (Palanisamy et al., 2010). In this study, Nephe/ium lappaceum was extracted using a different organic solvents and were tested for antiproliferative effect on several cancer cell lines using methylene blue assay. The purpose of this study was to determine the antiproliferative activity of organic extracts of Nephelium lappaceum peels on selected cancer cell lines. Pusat Pengajian Sains Perubatan, Universiti Sains Malaysia 2011 Monograph NonPeerReviewed application/pdf en http://eprints.usm.my/53444/1/DR%20MOHD%20DASUKI%20SUL%27AIN-Eprints.pdf Sul'ain, Mohd Dasuki (2011) A study on antiproliferative activity of methanolic extract of Nephelium lappaceum peel towards selected cancer cell lines. Other. Pusat Pengajian Sains Perubatan, Universiti Sains Malaysia. (Submitted)
spellingShingle R Medicine
Sul'ain, Mohd Dasuki
A study on antiproliferative activity of methanolic extract of Nephelium lappaceum peel towards selected cancer cell lines
title A study on antiproliferative activity of methanolic extract of Nephelium lappaceum peel towards selected cancer cell lines
title_full A study on antiproliferative activity of methanolic extract of Nephelium lappaceum peel towards selected cancer cell lines
title_fullStr A study on antiproliferative activity of methanolic extract of Nephelium lappaceum peel towards selected cancer cell lines
title_full_unstemmed A study on antiproliferative activity of methanolic extract of Nephelium lappaceum peel towards selected cancer cell lines
title_short A study on antiproliferative activity of methanolic extract of Nephelium lappaceum peel towards selected cancer cell lines
title_sort study on antiproliferative activity of methanolic extract of nephelium lappaceum peel towards selected cancer cell lines
topic R Medicine
url http://eprints.usm.my/53444/
http://eprints.usm.my/53444/1/DR%20MOHD%20DASUKI%20SUL%27AIN-Eprints.pdf