In Vitro And In Vivo Study On The Identification Of Compounds That Alleviate Aβ42 Associated Neurodegeneration
Alzheimer’s disease (AD) is the most common type of neurological disorder globally. Its mechanism includes the distinctive aggregation of extracellular senile plaques made up of amyloid-beta (Aβ) in the brain. Among the Aβ isomers secreted in the brain, Aβ42 is the most neurotoxic and aggressive. R...
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| Format: | Thesis |
| Language: | English |
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2020
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| Online Access: | http://eprints.usm.my/53394/ http://eprints.usm.my/53394/1/FLORENCE%20TAN%20HUI%20PING%20-%20TESIS.pdf%20cut.pdf |
| _version_ | 1848882517089714176 |
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| author | Tan, Florence Hui Ping |
| author_facet | Tan, Florence Hui Ping |
| author_sort | Tan, Florence Hui Ping |
| building | USM Institutional Repository |
| collection | Online Access |
| description | Alzheimer’s disease (AD) is the most common type of neurological disorder globally. Its mechanism includes the distinctive aggregation of extracellular senile
plaques made up of amyloid-beta (Aβ) in the brain. Among the Aβ isomers secreted in the brain, Aβ42 is the most neurotoxic and aggressive. Regardless of the immense
research on AD, the full pathogenesis of this disease remains unknown. The main aim of this study was to identify compounds that are able to alleviate Aβ42’s negative effects. |
| first_indexed | 2025-11-15T18:36:10Z |
| format | Thesis |
| id | usm-53394 |
| institution | Universiti Sains Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T18:36:10Z |
| publishDate | 2020 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | usm-533942022-07-15T08:33:47Z http://eprints.usm.my/53394/ In Vitro And In Vivo Study On The Identification Of Compounds That Alleviate Aβ42 Associated Neurodegeneration Tan, Florence Hui Ping RS1-441 Pharmacy and materia medica Alzheimer’s disease (AD) is the most common type of neurological disorder globally. Its mechanism includes the distinctive aggregation of extracellular senile plaques made up of amyloid-beta (Aβ) in the brain. Among the Aβ isomers secreted in the brain, Aβ42 is the most neurotoxic and aggressive. Regardless of the immense research on AD, the full pathogenesis of this disease remains unknown. The main aim of this study was to identify compounds that are able to alleviate Aβ42’s negative effects. 2020-12 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/53394/1/FLORENCE%20TAN%20HUI%20PING%20-%20TESIS.pdf%20cut.pdf Tan, Florence Hui Ping (2020) In Vitro And In Vivo Study On The Identification Of Compounds That Alleviate Aβ42 Associated Neurodegeneration. PhD thesis, Universiti Sains Malaysia. |
| spellingShingle | RS1-441 Pharmacy and materia medica Tan, Florence Hui Ping In Vitro And In Vivo Study On The Identification Of Compounds That Alleviate Aβ42 Associated Neurodegeneration |
| title | In Vitro And In Vivo Study On The Identification Of Compounds That Alleviate Aβ42 Associated Neurodegeneration |
| title_full | In Vitro And In Vivo Study On The Identification Of Compounds That Alleviate Aβ42 Associated Neurodegeneration |
| title_fullStr | In Vitro And In Vivo Study On The Identification Of Compounds That Alleviate Aβ42 Associated Neurodegeneration |
| title_full_unstemmed | In Vitro And In Vivo Study On The Identification Of Compounds That Alleviate Aβ42 Associated Neurodegeneration |
| title_short | In Vitro And In Vivo Study On The Identification Of Compounds That Alleviate Aβ42 Associated Neurodegeneration |
| title_sort | in vitro and in vivo study on the identification of compounds that alleviate aβ42 associated neurodegeneration |
| topic | RS1-441 Pharmacy and materia medica |
| url | http://eprints.usm.my/53394/ http://eprints.usm.my/53394/1/FLORENCE%20TAN%20HUI%20PING%20-%20TESIS.pdf%20cut.pdf |