Expression Of PhaC1 And PhaC2 From Pseudomonas Sp. USM4-55 In Escherichia Coli Expression System

Polyhydroxyalkanoates (PHAs) are synthesized intracelullarly by a variety of microorganisms as reserve materials for carbon and energy source. PHA synthase (PhaC) is the key enzyme in the polymerization of PHAs. Pseudomonas sp. USM4-55 is a local isolate which is able to produce a blend of short...

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Main Author: Ghani, Balqis Ab.
Format: Thesis
Language:English
Published: 2007
Subjects:
Online Access:http://eprints.usm.my/53174/
http://eprints.usm.my/53174/1/Tesis%20expression%20of%20phaC1%20cut.pdf
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author Ghani, Balqis Ab.
author_facet Ghani, Balqis Ab.
author_sort Ghani, Balqis Ab.
building USM Institutional Repository
collection Online Access
description Polyhydroxyalkanoates (PHAs) are synthesized intracelullarly by a variety of microorganisms as reserve materials for carbon and energy source. PHA synthase (PhaC) is the key enzyme in the polymerization of PHAs. Pseudomonas sp. USM4-55 is a local isolate which is able to produce a blend of short chain length and medium chain length of polymer. Genes coding for PhaC (phaC1 and phaC2) from Pseudomonas sp. USM4-55 were amplified (each with a size of 1.7 kb) from the genomic DNA, cloned into pGEMR-T for sequencing and then expressed. For expression studies, pQE-30 was used as the expression vector under the control of PT5 promoter. These clones were named pQE-C1 and pQE-C2, and were induced with 0.01 mM of isopropyl-p-Dthiogalactoside (IPTG) at ODeoo of 0.6.
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institution Universiti Sains Malaysia
institution_category Local University
language English
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publishDate 2007
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spelling usm-531742022-06-29T02:52:05Z http://eprints.usm.my/53174/ Expression Of PhaC1 And PhaC2 From Pseudomonas Sp. USM4-55 In Escherichia Coli Expression System Ghani, Balqis Ab. QH1 Natural history (General - Including nature conservation, geographical distribution) Polyhydroxyalkanoates (PHAs) are synthesized intracelullarly by a variety of microorganisms as reserve materials for carbon and energy source. PHA synthase (PhaC) is the key enzyme in the polymerization of PHAs. Pseudomonas sp. USM4-55 is a local isolate which is able to produce a blend of short chain length and medium chain length of polymer. Genes coding for PhaC (phaC1 and phaC2) from Pseudomonas sp. USM4-55 were amplified (each with a size of 1.7 kb) from the genomic DNA, cloned into pGEMR-T for sequencing and then expressed. For expression studies, pQE-30 was used as the expression vector under the control of PT5 promoter. These clones were named pQE-C1 and pQE-C2, and were induced with 0.01 mM of isopropyl-p-Dthiogalactoside (IPTG) at ODeoo of 0.6. 2007-09 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/53174/1/Tesis%20expression%20of%20phaC1%20cut.pdf Ghani, Balqis Ab. (2007) Expression Of PhaC1 And PhaC2 From Pseudomonas Sp. USM4-55 In Escherichia Coli Expression System. Masters thesis, Universiti Sains Malaysia.
spellingShingle QH1 Natural history (General - Including nature conservation, geographical distribution)
Ghani, Balqis Ab.
Expression Of PhaC1 And PhaC2 From Pseudomonas Sp. USM4-55 In Escherichia Coli Expression System
title Expression Of PhaC1 And PhaC2 From Pseudomonas Sp. USM4-55 In Escherichia Coli Expression System
title_full Expression Of PhaC1 And PhaC2 From Pseudomonas Sp. USM4-55 In Escherichia Coli Expression System
title_fullStr Expression Of PhaC1 And PhaC2 From Pseudomonas Sp. USM4-55 In Escherichia Coli Expression System
title_full_unstemmed Expression Of PhaC1 And PhaC2 From Pseudomonas Sp. USM4-55 In Escherichia Coli Expression System
title_short Expression Of PhaC1 And PhaC2 From Pseudomonas Sp. USM4-55 In Escherichia Coli Expression System
title_sort expression of phac1 and phac2 from pseudomonas sp. usm4-55 in escherichia coli expression system
topic QH1 Natural history (General - Including nature conservation, geographical distribution)
url http://eprints.usm.my/53174/
http://eprints.usm.my/53174/1/Tesis%20expression%20of%20phaC1%20cut.pdf