Multi-Doping Of Mg-Co Substituted Carbonated Hydroxyapatite For Biomedical Applications
Carbonated hydroxyapatite (CHA) is a promising biomaterials that is suitable to be used as bone substitution. However, CHA has limitation, as it has low thermal stability. Thus, this study was conducted to investigate the effect of multi-doped CHA through chemical, mechanical, physical and biologica...
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| Format: | Monograph |
| Language: | English |
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Universiti Sains Malaysia
2017
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| Online Access: | http://eprints.usm.my/52747/ http://eprints.usm.my/52747/2/Multi-Doping%20Of%20Mg-Co%20Substituted%20Carbonated%20Hydroxyapatite%20For%20Biomedical%20Applications_Syahidah%20Suhaili%20Yahaya_B1_2017.pdf |
| _version_ | 1848882337065992192 |
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| author | Yahaya, Syahidah Suhaili |
| author_facet | Yahaya, Syahidah Suhaili |
| author_sort | Yahaya, Syahidah Suhaili |
| building | USM Institutional Repository |
| collection | Online Access |
| description | Carbonated hydroxyapatite (CHA) is a promising biomaterials that is suitable to be used as bone substitution. However, CHA has limitation, as it has low thermal stability. Thus, this study was conducted to investigate the effect of multi-doped CHA through chemical, mechanical, physical and biological analysis. Multi-doped CHA was successfully synthesis via nanoemulsion method, through direct pouring technique, followed by characterizations of the produced powders. It was found that Mg-Co CHA 1 and Mg-Co CHA 2 had the optimum compositions. The powders produced were B-type CHA. These powders were then fabricated by dry pressing method and sintered at 900°C. Dry carbon dioxide (CO2) gas was supplied to the sample after cooled down to 200°C to compensate carbonate decomposition during sintering. Used of dry CO2 had successfully compensate the carbonate decomposition during sintering. The sintered samples were maintained as B-type CHA. In vitro bioactivity test also was done for sintered multi-doped CHA for seven days. SEM observation for dense multi-doped CHA after seven days showed that apatite layer were successfully formed for all compositions. Thus, the optimum composition that produced high amount of apatite layer, good chemical, mechanical and physical properties is Mg-Co CHA 2, where magnesium in maximum amount and cobalt in minimum amount. |
| first_indexed | 2025-11-15T18:33:18Z |
| format | Monograph |
| id | usm-52747 |
| institution | Universiti Sains Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T18:33:18Z |
| publishDate | 2017 |
| publisher | Universiti Sains Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | usm-527472022-06-03T03:22:25Z http://eprints.usm.my/52747/ Multi-Doping Of Mg-Co Substituted Carbonated Hydroxyapatite For Biomedical Applications Yahaya, Syahidah Suhaili T Technology TA401-492 Materials of engineering and construction. Mechanics of materials Carbonated hydroxyapatite (CHA) is a promising biomaterials that is suitable to be used as bone substitution. However, CHA has limitation, as it has low thermal stability. Thus, this study was conducted to investigate the effect of multi-doped CHA through chemical, mechanical, physical and biological analysis. Multi-doped CHA was successfully synthesis via nanoemulsion method, through direct pouring technique, followed by characterizations of the produced powders. It was found that Mg-Co CHA 1 and Mg-Co CHA 2 had the optimum compositions. The powders produced were B-type CHA. These powders were then fabricated by dry pressing method and sintered at 900°C. Dry carbon dioxide (CO2) gas was supplied to the sample after cooled down to 200°C to compensate carbonate decomposition during sintering. Used of dry CO2 had successfully compensate the carbonate decomposition during sintering. The sintered samples were maintained as B-type CHA. In vitro bioactivity test also was done for sintered multi-doped CHA for seven days. SEM observation for dense multi-doped CHA after seven days showed that apatite layer were successfully formed for all compositions. Thus, the optimum composition that produced high amount of apatite layer, good chemical, mechanical and physical properties is Mg-Co CHA 2, where magnesium in maximum amount and cobalt in minimum amount. Universiti Sains Malaysia 2017-07-01 Monograph NonPeerReviewed application/pdf en http://eprints.usm.my/52747/2/Multi-Doping%20Of%20Mg-Co%20Substituted%20Carbonated%20Hydroxyapatite%20For%20Biomedical%20Applications_Syahidah%20Suhaili%20Yahaya_B1_2017.pdf Yahaya, Syahidah Suhaili (2017) Multi-Doping Of Mg-Co Substituted Carbonated Hydroxyapatite For Biomedical Applications. Project Report. Universiti Sains Malaysia, Pusat Pengajian Kejuruteraan Bahan Sumber Mineral. (Submitted) |
| spellingShingle | T Technology TA401-492 Materials of engineering and construction. Mechanics of materials Yahaya, Syahidah Suhaili Multi-Doping Of Mg-Co Substituted Carbonated Hydroxyapatite For Biomedical Applications |
| title | Multi-Doping Of Mg-Co Substituted Carbonated Hydroxyapatite For Biomedical Applications |
| title_full | Multi-Doping Of Mg-Co Substituted Carbonated Hydroxyapatite For Biomedical Applications |
| title_fullStr | Multi-Doping Of Mg-Co Substituted Carbonated Hydroxyapatite For Biomedical Applications |
| title_full_unstemmed | Multi-Doping Of Mg-Co Substituted Carbonated Hydroxyapatite For Biomedical Applications |
| title_short | Multi-Doping Of Mg-Co Substituted Carbonated Hydroxyapatite For Biomedical Applications |
| title_sort | multi-doping of mg-co substituted carbonated hydroxyapatite for biomedical applications |
| topic | T Technology TA401-492 Materials of engineering and construction. Mechanics of materials |
| url | http://eprints.usm.my/52747/ http://eprints.usm.my/52747/2/Multi-Doping%20Of%20Mg-Co%20Substituted%20Carbonated%20Hydroxyapatite%20For%20Biomedical%20Applications_Syahidah%20Suhaili%20Yahaya_B1_2017.pdf |