Electron Transport Studies In 12-mer Single Strand Dna Oligomers By Muon Spetroscopy And Scanning Tunneling Microscopy

The aims of this study are to determine which of the four samples of 12-mer single-strand: adenine, cytosine, guanine, and thymine (ssA12, ssC12, ssG12, and ssT12) is the most and least conductive. Besides, to find out the behaviour of the electron transfer in these samples. Scanning tunneling micro...

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Main Author: Rozak, Harison
Format: Thesis
Language:English
Published: 2021
Subjects:
Online Access:http://eprints.usm.my/52697/
http://eprints.usm.my/52697/1/HARISON%20BINTI%20ROZAK%20-%20TESIS24.pdf
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author Rozak, Harison
author_facet Rozak, Harison
author_sort Rozak, Harison
building USM Institutional Repository
collection Online Access
description The aims of this study are to determine which of the four samples of 12-mer single-strand: adenine, cytosine, guanine, and thymine (ssA12, ssC12, ssG12, and ssT12) is the most and least conductive. Besides, to find out the behaviour of the electron transfer in these samples. Scanning tunneling microscope (STM) and muon spin relaxation (μSR) measurements were performed to achieve the objectives study. The STM technique was also used to determine the shape of each oligomer sample and to study the influence of environmental conditions on the conductivity measurement. From STM measurements, each base in DNA was found to be conductive, and the most conductive base is ssG12. The sequence of conductivity based on the tip-height profile (Hp) measurement is ssG12 > ssC12 > ssA12 > ssT12. The shapes of oligomers were observed to be different from each other because ssDNA12 samples (ssA12, ssC12, ssG12, and ssT12) are flexible structures as they are formed without any complement bases and strand. These oligomers were also seen aligned in parallel from each other and formed a one-dimensional (1D) chain structure. The μSR technique successfully detected the existence of electron transfer in ssDNA12. The behaviour of the electron transfer along the ssDNA12 was suggested in quasi-1D at room temperature. From conductivity measurement in different environment conditions on ssG12, it was found that conductivity did not depend on the environmental conditions. Overall, it can be suggested that ssDNA12 itself is conductive and they can be a medium for the electron to transfer
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format Thesis
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institution Universiti Sains Malaysia
institution_category Local University
language English
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publishDate 2021
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spelling usm-526972022-05-31T18:31:52Z http://eprints.usm.my/52697/ Electron Transport Studies In 12-mer Single Strand Dna Oligomers By Muon Spetroscopy And Scanning Tunneling Microscopy Rozak, Harison LC5800-5808 Distance education. The aims of this study are to determine which of the four samples of 12-mer single-strand: adenine, cytosine, guanine, and thymine (ssA12, ssC12, ssG12, and ssT12) is the most and least conductive. Besides, to find out the behaviour of the electron transfer in these samples. Scanning tunneling microscope (STM) and muon spin relaxation (μSR) measurements were performed to achieve the objectives study. The STM technique was also used to determine the shape of each oligomer sample and to study the influence of environmental conditions on the conductivity measurement. From STM measurements, each base in DNA was found to be conductive, and the most conductive base is ssG12. The sequence of conductivity based on the tip-height profile (Hp) measurement is ssG12 > ssC12 > ssA12 > ssT12. The shapes of oligomers were observed to be different from each other because ssDNA12 samples (ssA12, ssC12, ssG12, and ssT12) are flexible structures as they are formed without any complement bases and strand. These oligomers were also seen aligned in parallel from each other and formed a one-dimensional (1D) chain structure. The μSR technique successfully detected the existence of electron transfer in ssDNA12. The behaviour of the electron transfer along the ssDNA12 was suggested in quasi-1D at room temperature. From conductivity measurement in different environment conditions on ssG12, it was found that conductivity did not depend on the environmental conditions. Overall, it can be suggested that ssDNA12 itself is conductive and they can be a medium for the electron to transfer 2021-10 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/52697/1/HARISON%20BINTI%20ROZAK%20-%20TESIS24.pdf Rozak, Harison (2021) Electron Transport Studies In 12-mer Single Strand Dna Oligomers By Muon Spetroscopy And Scanning Tunneling Microscopy. PhD thesis, Universiti Sains Malaysia.
spellingShingle LC5800-5808 Distance education.
Rozak, Harison
Electron Transport Studies In 12-mer Single Strand Dna Oligomers By Muon Spetroscopy And Scanning Tunneling Microscopy
title Electron Transport Studies In 12-mer Single Strand Dna Oligomers By Muon Spetroscopy And Scanning Tunneling Microscopy
title_full Electron Transport Studies In 12-mer Single Strand Dna Oligomers By Muon Spetroscopy And Scanning Tunneling Microscopy
title_fullStr Electron Transport Studies In 12-mer Single Strand Dna Oligomers By Muon Spetroscopy And Scanning Tunneling Microscopy
title_full_unstemmed Electron Transport Studies In 12-mer Single Strand Dna Oligomers By Muon Spetroscopy And Scanning Tunneling Microscopy
title_short Electron Transport Studies In 12-mer Single Strand Dna Oligomers By Muon Spetroscopy And Scanning Tunneling Microscopy
title_sort electron transport studies in 12-mer single strand dna oligomers by muon spetroscopy and scanning tunneling microscopy
topic LC5800-5808 Distance education.
url http://eprints.usm.my/52697/
http://eprints.usm.my/52697/1/HARISON%20BINTI%20ROZAK%20-%20TESIS24.pdf