Iron Oxide Encapsulated Gold Colloidal Nanoparticle Via Rapid Sonochemical Method For Mri And Ct Imaging Application
Core@shell nanoparticles (Fe3O4@Au NPs) have multiple functions obtained in one stable entity and thus have been extensively investigated. Combining Fe3O4 and Au NPs in one core@shell nanostructure is a promising strategy for diagnostic biomedical applications. However, the conventional direct metho...
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| Format: | Thesis |
| Language: | English |
| Published: |
2021
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| Online Access: | http://eprints.usm.my/52055/ http://eprints.usm.my/52055/1/MOHAMMED%20ALI%20DHEYAB.pdf |
| _version_ | 1848882154628448256 |
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| author | Dheyab, Mohammed Ali |
| author_facet | Dheyab, Mohammed Ali |
| author_sort | Dheyab, Mohammed Ali |
| building | USM Institutional Repository |
| collection | Online Access |
| description | Core@shell nanoparticles (Fe3O4@Au NPs) have multiple functions obtained in one stable entity and thus have been extensively investigated. Combining Fe3O4 and Au NPs in one core@shell nanostructure is a promising strategy for diagnostic biomedical applications. However, the conventional direct methods for Fe3O4@Au NPs synthesis are laborious and time-consuming. Therefore, this study presents a facile and rapid sonochemical technique of synthesising Fe3O4@Au NPs with excellent physicochemical properties for magnetic resonance imaging (MRI) and computed tomography (CT) scan. The Au shell is coated on Fe3O4 NPs using a Vibra-Cell ultrasonic solid horn with tip size, frequency and power output of ½ inch, 20 kHz and 750 watts, respectively within 10 minutes. The targeted zeta potential of - 46.125 mV was achieved under the optimum conditions of 10 ml of HAuCl4, 30 ml of sodium citrate (SC) and sonication amplitude of 40%, which is consistent (about 99.2%) with the actual average zeta potential (- 45.8 mV). The stability and monodispersing of Fe3O4NPs improved following modification to Fe3O4@Au, as indicated by the increase in zeta potential from - 24.2 mV to - 45.8 mV. The saturation magnetization (Ms) value of Fe3O4 was 54 emu/g, while that of Fe3O4@Au NP is 38 emu/g. In general, the sonochemical method effectively synthesis highly stable and monodisperse Fe3O4@Au NPs with an average size of about 20 nm within 10 minutes. |
| first_indexed | 2025-11-15T18:30:24Z |
| format | Thesis |
| id | usm-52055 |
| institution | Universiti Sains Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T18:30:24Z |
| publishDate | 2021 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | usm-520552022-03-28T07:07:55Z http://eprints.usm.my/52055/ Iron Oxide Encapsulated Gold Colloidal Nanoparticle Via Rapid Sonochemical Method For Mri And Ct Imaging Application Dheyab, Mohammed Ali QC1 Physics (General) Core@shell nanoparticles (Fe3O4@Au NPs) have multiple functions obtained in one stable entity and thus have been extensively investigated. Combining Fe3O4 and Au NPs in one core@shell nanostructure is a promising strategy for diagnostic biomedical applications. However, the conventional direct methods for Fe3O4@Au NPs synthesis are laborious and time-consuming. Therefore, this study presents a facile and rapid sonochemical technique of synthesising Fe3O4@Au NPs with excellent physicochemical properties for magnetic resonance imaging (MRI) and computed tomography (CT) scan. The Au shell is coated on Fe3O4 NPs using a Vibra-Cell ultrasonic solid horn with tip size, frequency and power output of ½ inch, 20 kHz and 750 watts, respectively within 10 minutes. The targeted zeta potential of - 46.125 mV was achieved under the optimum conditions of 10 ml of HAuCl4, 30 ml of sodium citrate (SC) and sonication amplitude of 40%, which is consistent (about 99.2%) with the actual average zeta potential (- 45.8 mV). The stability and monodispersing of Fe3O4NPs improved following modification to Fe3O4@Au, as indicated by the increase in zeta potential from - 24.2 mV to - 45.8 mV. The saturation magnetization (Ms) value of Fe3O4 was 54 emu/g, while that of Fe3O4@Au NP is 38 emu/g. In general, the sonochemical method effectively synthesis highly stable and monodisperse Fe3O4@Au NPs with an average size of about 20 nm within 10 minutes. 2021-02 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/52055/1/MOHAMMED%20ALI%20DHEYAB.pdf Dheyab, Mohammed Ali (2021) Iron Oxide Encapsulated Gold Colloidal Nanoparticle Via Rapid Sonochemical Method For Mri And Ct Imaging Application. PhD thesis, Perpustakaan Hamzah Sendut. |
| spellingShingle | QC1 Physics (General) Dheyab, Mohammed Ali Iron Oxide Encapsulated Gold Colloidal Nanoparticle Via Rapid Sonochemical Method For Mri And Ct Imaging Application |
| title | Iron Oxide Encapsulated Gold Colloidal Nanoparticle Via Rapid Sonochemical Method For Mri And Ct Imaging Application |
| title_full | Iron Oxide Encapsulated Gold Colloidal Nanoparticle Via Rapid Sonochemical Method For Mri And Ct Imaging Application |
| title_fullStr | Iron Oxide Encapsulated Gold Colloidal Nanoparticle Via Rapid Sonochemical Method For Mri And Ct Imaging Application |
| title_full_unstemmed | Iron Oxide Encapsulated Gold Colloidal Nanoparticle Via Rapid Sonochemical Method For Mri And Ct Imaging Application |
| title_short | Iron Oxide Encapsulated Gold Colloidal Nanoparticle Via Rapid Sonochemical Method For Mri And Ct Imaging Application |
| title_sort | iron oxide encapsulated gold colloidal nanoparticle via rapid sonochemical method for mri and ct imaging application |
| topic | QC1 Physics (General) |
| url | http://eprints.usm.my/52055/ http://eprints.usm.my/52055/1/MOHAMMED%20ALI%20DHEYAB.pdf |