Genetic relationship among the three negrito (seman g) tribes of peninsular malaysia: microsa tellite analysis

The struggle to determine susceptibility genes for complex disorders has stimulated geneticists to develop new approaches. The genetic markers rapidly superseded by microsatellites since they prolifically throughout the genome and are highly variable in repeat length and polymorphisms. The Negrit...

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Main Author: Mohd Redhuan, Mohd Noor
Format: Monograph
Language:English
Published: Universiti Sains Malaysia 2008
Subjects:
Online Access:http://eprints.usm.my/48862/
http://eprints.usm.my/48862/1/MOHD%20REDHUAN%20BIN%20MOHD%20NOOR%20-%2024%20pages.pdf
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author Mohd Redhuan, Mohd Noor
author_facet Mohd Redhuan, Mohd Noor
author_sort Mohd Redhuan, Mohd Noor
building USM Institutional Repository
collection Online Access
description The struggle to determine susceptibility genes for complex disorders has stimulated geneticists to develop new approaches. The genetic markers rapidly superseded by microsatellites since they prolifically throughout the genome and are highly variable in repeat length and polymorphisms. The Negritos, believed to be the first aborigines arrived at Peninsular Malaysia, somewhat I 0,000 years ago was thought to be related to Andaman islanders and Nicobar Islands. They are divided into six groups, namely Kensiu, Bateq, Mendriq, Jahai, Lanoh and Kintak. In this study, an attempt was made to optimize the locus D 198220 for GeneS can Analysis purpose. Marker was selected from Genethon Microsatellite Map (http://www.genlink.wustl.edu/genethon_frame/). DNA was extracted from the samples collected from three Negrito Tribes in Kelantan: Jahai, Mendriq and Bateq. A series of PCR optimization were done and run on the ABI 3100 capillary based genetic analyzer. PCR was then amplified on the Mendriq population in order to examine the PCR condition optimized. iii
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spelling usm-488622021-04-13T03:42:35Z http://eprints.usm.my/48862/ Genetic relationship among the three negrito (seman g) tribes of peninsular malaysia: microsa tellite analysis Mohd Redhuan, Mohd Noor R Medicine (General) The struggle to determine susceptibility genes for complex disorders has stimulated geneticists to develop new approaches. The genetic markers rapidly superseded by microsatellites since they prolifically throughout the genome and are highly variable in repeat length and polymorphisms. The Negritos, believed to be the first aborigines arrived at Peninsular Malaysia, somewhat I 0,000 years ago was thought to be related to Andaman islanders and Nicobar Islands. They are divided into six groups, namely Kensiu, Bateq, Mendriq, Jahai, Lanoh and Kintak. In this study, an attempt was made to optimize the locus D 198220 for GeneS can Analysis purpose. Marker was selected from Genethon Microsatellite Map (http://www.genlink.wustl.edu/genethon_frame/). DNA was extracted from the samples collected from three Negrito Tribes in Kelantan: Jahai, Mendriq and Bateq. A series of PCR optimization were done and run on the ABI 3100 capillary based genetic analyzer. PCR was then amplified on the Mendriq population in order to examine the PCR condition optimized. iii Universiti Sains Malaysia 2008-03 Monograph NonPeerReviewed application/pdf en http://eprints.usm.my/48862/1/MOHD%20REDHUAN%20BIN%20MOHD%20NOOR%20-%2024%20pages.pdf Mohd Redhuan, Mohd Noor (2008) Genetic relationship among the three negrito (seman g) tribes of peninsular malaysia: microsa tellite analysis. Other. Universiti Sains Malaysia. (Submitted)
spellingShingle R Medicine (General)
Mohd Redhuan, Mohd Noor
Genetic relationship among the three negrito (seman g) tribes of peninsular malaysia: microsa tellite analysis
title Genetic relationship among the three negrito (seman g) tribes of peninsular malaysia: microsa tellite analysis
title_full Genetic relationship among the three negrito (seman g) tribes of peninsular malaysia: microsa tellite analysis
title_fullStr Genetic relationship among the three negrito (seman g) tribes of peninsular malaysia: microsa tellite analysis
title_full_unstemmed Genetic relationship among the three negrito (seman g) tribes of peninsular malaysia: microsa tellite analysis
title_short Genetic relationship among the three negrito (seman g) tribes of peninsular malaysia: microsa tellite analysis
title_sort genetic relationship among the three negrito (seman g) tribes of peninsular malaysia: microsa tellite analysis
topic R Medicine (General)
url http://eprints.usm.my/48862/
http://eprints.usm.my/48862/1/MOHD%20REDHUAN%20BIN%20MOHD%20NOOR%20-%2024%20pages.pdf