Classification of Haplogroup C and Haplogroup D in Modern Malay and Chinese population of Peninsular Malaysia

Mitochondrial DNA analysis is carried out for 45 samples from modem Malay and 44 samples from modem Chinese populations of Peninsula Malaysia. The mitochondrial DNA coding region variation of these samples was examined using restriction fragment length polymorphism (RFLP) method. From the analysi...

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Main Author: Atan, Edinur Hisham
Format: Monograph
Language:English
Published: Universiti Sains Malaysia 2006
Subjects:
Online Access:http://eprints.usm.my/48505/
http://eprints.usm.my/48505/1/EDINUR%20HISHAM%20BIN%20ATAN.pdf
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author Atan, Edinur Hisham
author_facet Atan, Edinur Hisham
author_sort Atan, Edinur Hisham
building USM Institutional Repository
collection Online Access
description Mitochondrial DNA analysis is carried out for 45 samples from modem Malay and 44 samples from modem Chinese populations of Peninsula Malaysia. The mitochondrial DNA coding region variation of these samples was examined using restriction fragment length polymorphism (RFLP) method. From the analysis of Alu I site gain nucleotide position 10397, 37.78% of modem Malay population of peninsular Malaysia belongs to superhaplogroup M while 4 7. 73% of the modem Chinese belong to superhaplogroup M. Superhaplogroup M is further divided into several haplogroup, which are defined by the presence of specific RFLP markers. Haplogroup C and Haplogroup D are determined by the presence of Alu l restriction site at the nucleotide position 13 262 and the absence of Alu 1 restriction site at the nucleotide position 5 176. For Modem Malay population, only 8.89% of the sample belongs to the haplogroup D while none belong to the haplogroup C. For modem Chinese population of peninsular Malaysia, 4.65% of the samples belong to haplogroup C and 6.82% of the samples belong to the haplogroup D.
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format Monograph
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institution Universiti Sains Malaysia
institution_category Local University
language English
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publishDate 2006
publisher Universiti Sains Malaysia
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spelling usm-485052021-03-02T07:17:11Z http://eprints.usm.my/48505/ Classification of Haplogroup C and Haplogroup D in Modern Malay and Chinese population of Peninsular Malaysia Atan, Edinur Hisham R Medicine (General) Mitochondrial DNA analysis is carried out for 45 samples from modem Malay and 44 samples from modem Chinese populations of Peninsula Malaysia. The mitochondrial DNA coding region variation of these samples was examined using restriction fragment length polymorphism (RFLP) method. From the analysis of Alu I site gain nucleotide position 10397, 37.78% of modem Malay population of peninsular Malaysia belongs to superhaplogroup M while 4 7. 73% of the modem Chinese belong to superhaplogroup M. Superhaplogroup M is further divided into several haplogroup, which are defined by the presence of specific RFLP markers. Haplogroup C and Haplogroup D are determined by the presence of Alu l restriction site at the nucleotide position 13 262 and the absence of Alu 1 restriction site at the nucleotide position 5 176. For Modem Malay population, only 8.89% of the sample belongs to the haplogroup D while none belong to the haplogroup C. For modem Chinese population of peninsular Malaysia, 4.65% of the samples belong to haplogroup C and 6.82% of the samples belong to the haplogroup D. Universiti Sains Malaysia 2006-05 Monograph NonPeerReviewed application/pdf en http://eprints.usm.my/48505/1/EDINUR%20HISHAM%20BIN%20ATAN.pdf Atan, Edinur Hisham (2006) Classification of Haplogroup C and Haplogroup D in Modern Malay and Chinese population of Peninsular Malaysia. Other. Universiti Sains Malaysia. (Submitted)
spellingShingle R Medicine (General)
Atan, Edinur Hisham
Classification of Haplogroup C and Haplogroup D in Modern Malay and Chinese population of Peninsular Malaysia
title Classification of Haplogroup C and Haplogroup D in Modern Malay and Chinese population of Peninsular Malaysia
title_full Classification of Haplogroup C and Haplogroup D in Modern Malay and Chinese population of Peninsular Malaysia
title_fullStr Classification of Haplogroup C and Haplogroup D in Modern Malay and Chinese population of Peninsular Malaysia
title_full_unstemmed Classification of Haplogroup C and Haplogroup D in Modern Malay and Chinese population of Peninsular Malaysia
title_short Classification of Haplogroup C and Haplogroup D in Modern Malay and Chinese population of Peninsular Malaysia
title_sort classification of haplogroup c and haplogroup d in modern malay and chinese population of peninsular malaysia
topic R Medicine (General)
url http://eprints.usm.my/48505/
http://eprints.usm.my/48505/1/EDINUR%20HISHAM%20BIN%20ATAN.pdf