Polymorphism of CSF1 PO, TH01 and TPOX in random Bajau Population of Malaysia

Genotype polymorphism studies at three short tandems repeat (STR) loci (CSF1 PO, TPOX, TH01) were carried out in one ethnic (Bajau) living in Sabah, Malaysia. The analysis was performed on 150 unrelated healthy individuals belonging to Bajau races. The allele frequency of each locus was calculate...

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Main Author: Minsun, Lelyan Minsun
Format: Monograph
Language:English
Published: Universiti Sains Malaysia 2006
Subjects:
Online Access:http://eprints.usm.my/48496/
http://eprints.usm.my/48496/1/Lelyan%20Binti%20Minsun.pdf
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author Minsun, Lelyan Minsun
author_facet Minsun, Lelyan Minsun
author_sort Minsun, Lelyan Minsun
building USM Institutional Repository
collection Online Access
description Genotype polymorphism studies at three short tandems repeat (STR) loci (CSF1 PO, TPOX, TH01) were carried out in one ethnic (Bajau) living in Sabah, Malaysia. The analysis was performed on 150 unrelated healthy individuals belonging to Bajau races. The allele frequency of each locus was calculated from the observed number of each genotype. All loci were in accordance with HardyWeinberg equilibrium (P = 0.05). No deviations from equilibrium were observed. The discriminatory power and exclusion probability values for all the analyzed markers are significantly high and thus reveal high forensic significance. Statistical analysis was also carried out to obtain some parameters of medico-legal interest and comparative studies were carried out with other populations studied to date for these loci. This allele frequency data will be useful for forensic analyses and paternity analysis to estimate the frequency of a multiple STR locus DNA profile in Bajau population.
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institution Universiti Sains Malaysia
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language English
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publishDate 2006
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spelling usm-484962021-03-02T03:18:24Z http://eprints.usm.my/48496/ Polymorphism of CSF1 PO, TH01 and TPOX in random Bajau Population of Malaysia Minsun, Lelyan Minsun R Medicine (General) Genotype polymorphism studies at three short tandems repeat (STR) loci (CSF1 PO, TPOX, TH01) were carried out in one ethnic (Bajau) living in Sabah, Malaysia. The analysis was performed on 150 unrelated healthy individuals belonging to Bajau races. The allele frequency of each locus was calculated from the observed number of each genotype. All loci were in accordance with HardyWeinberg equilibrium (P = 0.05). No deviations from equilibrium were observed. The discriminatory power and exclusion probability values for all the analyzed markers are significantly high and thus reveal high forensic significance. Statistical analysis was also carried out to obtain some parameters of medico-legal interest and comparative studies were carried out with other populations studied to date for these loci. This allele frequency data will be useful for forensic analyses and paternity analysis to estimate the frequency of a multiple STR locus DNA profile in Bajau population. Universiti Sains Malaysia 2006 Monograph NonPeerReviewed application/pdf en http://eprints.usm.my/48496/1/Lelyan%20Binti%20Minsun.pdf Minsun, Lelyan Minsun (2006) Polymorphism of CSF1 PO, TH01 and TPOX in random Bajau Population of Malaysia. Other. Universiti Sains Malaysia. (Submitted)
spellingShingle R Medicine (General)
Minsun, Lelyan Minsun
Polymorphism of CSF1 PO, TH01 and TPOX in random Bajau Population of Malaysia
title Polymorphism of CSF1 PO, TH01 and TPOX in random Bajau Population of Malaysia
title_full Polymorphism of CSF1 PO, TH01 and TPOX in random Bajau Population of Malaysia
title_fullStr Polymorphism of CSF1 PO, TH01 and TPOX in random Bajau Population of Malaysia
title_full_unstemmed Polymorphism of CSF1 PO, TH01 and TPOX in random Bajau Population of Malaysia
title_short Polymorphism of CSF1 PO, TH01 and TPOX in random Bajau Population of Malaysia
title_sort polymorphism of csf1 po, th01 and tpox in random bajau population of malaysia
topic R Medicine (General)
url http://eprints.usm.my/48496/
http://eprints.usm.my/48496/1/Lelyan%20Binti%20Minsun.pdf