Levels Of Perfluorooctane Sulfonate (Pfos) And Perfluorooctanoic Acid (Pfoa) In Home And Commercially Produced Poultry Eggs In Malaysia

Perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) are the two major perfluorinated compounds (PFCs), widely used in industrial and consumer products pertaining to their unique water and grease repellent properties. The large industrial manufacture of these compounds had raised subst...

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Main Author: Tahziz, Atiqah
Format: Thesis
Language:English
Published: 2019
Subjects:
Online Access:http://eprints.usm.my/48075/
http://eprints.usm.my/48075/1/ATIQAH%20TAHZIZ_hj.pdf
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author Tahziz, Atiqah
author_facet Tahziz, Atiqah
author_sort Tahziz, Atiqah
building USM Institutional Repository
collection Online Access
description Perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) are the two major perfluorinated compounds (PFCs), widely used in industrial and consumer products pertaining to their unique water and grease repellent properties. The large industrial manufacture of these compounds had raised substantial concern on health effects, due to their persistence nature and potential toxicity. The bioaccumulative properties resulted in their accumulation in environmental matrices, human samples, as well as in food sources and food products. In human, food consumption was reportedly to be a significant source of exposure for both PFOS and PFOA. Hence, the primary objective of this study was to determine the level of PFOS and PFOA in the yolk of poultry eggs in Malaysia. A total of 47 egg yolk samples, consisting of chicken eggs (n=40), duck eggs (n=3) and quail eggs (n=4) were collected from various sources of areas in Malaysia. These samples are extracted by simple protein precipitation technique using acetonitrile. The analytical method was developed using LC-MS/MS and validated based on FDA’s Bioanalytical Method Validation to ensure the quality and reliability of the method. The analysis of the samples revealed that PFOS was quantitatively detected in six samples with the concentration range between 0.5 to 1.01 ng g-1. Among these, five samples are from home produced chicken eggs, and one sample was from a quail egg.
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spelling usm-480752021-01-11T08:51:25Z http://eprints.usm.my/48075/ Levels Of Perfluorooctane Sulfonate (Pfos) And Perfluorooctanoic Acid (Pfoa) In Home And Commercially Produced Poultry Eggs In Malaysia Tahziz, Atiqah R735-854 Medical education. Medical schools. Research Perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) are the two major perfluorinated compounds (PFCs), widely used in industrial and consumer products pertaining to their unique water and grease repellent properties. The large industrial manufacture of these compounds had raised substantial concern on health effects, due to their persistence nature and potential toxicity. The bioaccumulative properties resulted in their accumulation in environmental matrices, human samples, as well as in food sources and food products. In human, food consumption was reportedly to be a significant source of exposure for both PFOS and PFOA. Hence, the primary objective of this study was to determine the level of PFOS and PFOA in the yolk of poultry eggs in Malaysia. A total of 47 egg yolk samples, consisting of chicken eggs (n=40), duck eggs (n=3) and quail eggs (n=4) were collected from various sources of areas in Malaysia. These samples are extracted by simple protein precipitation technique using acetonitrile. The analytical method was developed using LC-MS/MS and validated based on FDA’s Bioanalytical Method Validation to ensure the quality and reliability of the method. The analysis of the samples revealed that PFOS was quantitatively detected in six samples with the concentration range between 0.5 to 1.01 ng g-1. Among these, five samples are from home produced chicken eggs, and one sample was from a quail egg. 2019 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/48075/1/ATIQAH%20TAHZIZ_hj.pdf Tahziz, Atiqah (2019) Levels Of Perfluorooctane Sulfonate (Pfos) And Perfluorooctanoic Acid (Pfoa) In Home And Commercially Produced Poultry Eggs In Malaysia. Masters thesis, Universiti Sains Malaysia.
spellingShingle R735-854 Medical education. Medical schools. Research
Tahziz, Atiqah
Levels Of Perfluorooctane Sulfonate (Pfos) And Perfluorooctanoic Acid (Pfoa) In Home And Commercially Produced Poultry Eggs In Malaysia
title Levels Of Perfluorooctane Sulfonate (Pfos) And Perfluorooctanoic Acid (Pfoa) In Home And Commercially Produced Poultry Eggs In Malaysia
title_full Levels Of Perfluorooctane Sulfonate (Pfos) And Perfluorooctanoic Acid (Pfoa) In Home And Commercially Produced Poultry Eggs In Malaysia
title_fullStr Levels Of Perfluorooctane Sulfonate (Pfos) And Perfluorooctanoic Acid (Pfoa) In Home And Commercially Produced Poultry Eggs In Malaysia
title_full_unstemmed Levels Of Perfluorooctane Sulfonate (Pfos) And Perfluorooctanoic Acid (Pfoa) In Home And Commercially Produced Poultry Eggs In Malaysia
title_short Levels Of Perfluorooctane Sulfonate (Pfos) And Perfluorooctanoic Acid (Pfoa) In Home And Commercially Produced Poultry Eggs In Malaysia
title_sort levels of perfluorooctane sulfonate (pfos) and perfluorooctanoic acid (pfoa) in home and commercially produced poultry eggs in malaysia
topic R735-854 Medical education. Medical schools. Research
url http://eprints.usm.my/48075/
http://eprints.usm.my/48075/1/ATIQAH%20TAHZIZ_hj.pdf