Elucidating The Diagnostic And Therapeutic Potential Of An RNA Aptamer Against Human Pituitary Tumour Transforming Gene 1

QR Code

Elucidating The Diagnostic And Therapeutic Potential Of An RNA Aptamer Against Human Pituitary Tumour Transforming Gene 1

Nucleic acid aptamers are a class of molecular recognition elements capable of target interaction at high specificity and affinity. This study was aimed to generate an RNA aptamer against the Human Pituitary Tumour Transforming Gene 1 (PTTG1) oncoprotein which can serve as a potential diagnostic and...

Full description

Bibliographic Details
Main Author:	Sankar, Prabu Siva
Format:	Thesis
Language:	English
Published:	2019
Subjects:	R5-920 Medicine (General)
Online Access:	http://eprints.usm.my/46406/ http://eprints.usm.my/46406/1/PRABU%20SIVA%20SANKAR_HJ.pdf

Similar Items

Development Of Dna Aptamer Against Envelope 2 Protein Of Chikungunya Virus And Their Diagnostic Potentiality
by: Andrew, Anna
Published: (2024)

Isolation And Characterization Of Aptamers Against Leptospira Lipl32
by: Yeoh, Tzi Shien
Published: (2023)

Elucidation of the mechanism involves in norovirus subgenomic RNA (sgRNA) synthesis:A rationale for attenuation in vaccine development.
by: Yunus, Muhammad Amir
Published: (2017)

Advances in aptamer-based biosensors and cell-internalizing SELEX technology for diagnostic and therapeutic application
by: Gan, Zixuen, et al.
Published: (2022)

Thiolated Alginate-Poly(Lactic-Co-Glycolic Acid) Aptamer-Functionalised As A Tamoxifen-Curcumin Nanocarrier Against Resistant Breast Cancer Cell
by: Chiu, Hock Ing
Published: (2023)

Characterization And In Vitro Study Of Protoporphyrin Ix (Haem) Aptamer In Reversing Drug-Resistant Malaria
by: Abdulwahab, Aliyu
Published: (2024)

Development Of Tcr-like Single Domain Antibody By Incorporating Immunoglobulin Isotypes For Latent Tuberculosis Diagnostics And Therapeutics Application Against Heat Shock Protein 16 Kda Peptide Presented By Hla-a2
by: Liu, Hua Qiang
Published: (2024)

Generation And Characterization Of Rna Aptamer Against rHuEPO-a By Selex Technology
by: Marimuthu, Citartan
Published: (2014)

Generation And Characterisation Of RNA Aptamers Against ESAT6 Protein From Mycobacterium Tuberculosis
by: Bukari, Bakhtiar Affendi
Published: (2017)

Generation And Characterization Of Rna Aptamer Against Dengue Virus 2 Ns1 Glycoprotein
by: Sivalingam, Rogini
Published: (2018)

Development of ssRNA for therapeutic gene knock-down
by: Powalowska, Paulina Klaudyna
Published: (2017)

Bzd9l1: Elucidation Of Its Anti-angiogenic Potential In In-vitro And In-vivo Colorectal Cancer Models
by: Subramaniam, Ayappa V.
Published: (2023)

Epidrug mediated re-expression of miRNA targeting the HMGA transcripts in pituitary cells
by: Kitchen, Mark O., et al.
Published: (2015)

Therapeutic Potential Of Menstrual Blood-Derived Endometrium Stem Cells On In Vitro And In Vivo Parkinson’s Disease Models
by: Li, Han
Published: (2019)

Aptamer‑functionalized MOFs and AI‑driven strategies for early cancer diagnosis and therapeutics
by: Futane, Abhishek, et al.
Published: (2024)

Transcription Start Site Mapping And Small Regulatory Rna Profiling Of Mycobacterium Tuberculosis
by: Cheah, Hong Leong
Published: (2022)

Effect Of Morinda Citrifolia (Linn.) On Phase I And Ii Drug Metabolism And Its Molecular Mechanism Elucidation In Rat Liver
by: Mohammed, Mahfoudh Al-Musli
Published: (2006)

Therapeutic Benefits Of Commercially Available Gourd Family In Improvement and Sustainability of Human Health
by: Mohd Ab Azid, Saffanah, et al.
Published: (2018)

Isolation of RNA aptamers specific toward 16 KDA mycobacterium tuberculosis antigen protein
by: Mohammed, Nurul Adila
Published: (2020)

Elucidating The In Vitro Antiproliferative Properties And Associated Mechanisms Of Momordica Cochinchinensis Spreng (Gac Fruit) Aqueous Extract Using Colorectal Cancer Origin Cell Lines
by: Thavamany, Priscilla Jayanthi
Published: (2024)

Synthesis and Advanced Characterisation of Nanoparticle Gene Delivery Systems for mRNA therapeutics
by: Khosravi, Rahman
Published: (2025)

In silico selection of aptamers against SARS-CoV-2
by: Akmal Shukri, Amir Muhaimin, et al.
Published: (2024)

Evaluation of the potential of Mycobacterium smegmatis as vaccine Candidate against tuberculosis by in silico and in vivo studies
by: Nguyen Thi, Le Thuy, et al.
Published: (2010)

Therapeutic Effects Of Extracellular Vesicles From Human Menstrual Blood-derived Mesenchymal Stem Cells In Acute Lung Injury Animal Model
by: Lian, Jie
Published: (2023)

Current Sudan protective practice in diagnostic nuclear medicine and patient dose
by: Edam, A.N., et al.
Published: (2021)

Elucidation of microRNA miR-6744-5p regulation of anoikis in breast cancer cell lines and potential for therapeutic applications / Sharan Malagobadan
by: Sharan , Malagobadan
Published: (2019)

In silico screening of aptamers configuration against hepatitis B surface antigen
by: Sabri, Mohamad Zulkeflee, et al.
Published: (2019)

Development Of Salmonella Typhi Ty21a As A Potential Oral Vaccine Against Tuberculosis : Surface Display And DNA Vaccine Carrier Of A Synthetic Multi-Epitope Mycobacterial Gene [RC311.4. A135 2004 f rb][Microfiche 7750].
by: Ahmad Sarhan, Mohammed Abdel Aziz
Published: (2004)

Molecular Characterization And Production Of A Specific Recombinant Protein Of Shigella Flexneri: Towards Development Of A Rapid Immunochromatography Diagnostic Test For Dysentery
by: Banga Singh, Kirnpal Kaur
Published: (2006)

Sequence-specific inhibition of microRNA-130a gene by CRISPR/Cas9 system in breast cancer cell line
by: Abdollah, Nur Ainina, et al.
Published: (2017)

The mRNA Expression Of Inducible Nitric Oxide Synthase In Keloid Using Tocotrienol-Rich Fraction In Primary Human Epidermal Keratinocytes And Primary Human Dermal Fibroblast Cultures
by: Yusuf, Siti Mahirah
Published: (2012)

Production And Characterization Of Recombinant Monoclonal Antibodies Against Toxocara Antigens
by: Baharudeen, Zamrina Mohd
Published: (2023)

Feasibility Of Complementary Metal Oxide Semiconductor (Cmos)-Based Time-Of-Flight (Tof) Image Sensors In Conjunction With Kilovoltage (Kv) Cone Beam Computed Tomography (Cbct) For Real-Time Tumour Tracking In Radiotherapy
by: Lim, Siew Yong @ Siew Eng
Published: (2022)

Understanding The Molecular Enteropathogenesis Of Martx Toxin Genes And Cholera Toxin Gene Mutations Of Vibrio Cholerae O139 Serogroup Towards Cholera Vaccine Development
by: Tan , Gim Cheong
Published: (2010)

Pituitary pathological review in 201 dogs and cats
by: Polledo, Laura
Published: (2018)

Pituitary Apoplexy: A rare cause of stroke
by: Hassan, Radhiana, et al.
Published: (2012)

Alternative RNA splicing: contribution to pain and potential therapeutic strategy
by: Donaldson, Lucy F., et al.
Published: (2016)

Fermentation Of Recombinant E. coli TOP10F' / pPROEX tm HTa / BmSXP To Achieve High Yield Of Biomass And Recombinant Antigen For Diagnostic Application
by: Khoo , Teng Kew
Published: (2011)

RNA interference therapeutics for cancer: challenges and opportunities
by: Bora, R., et al.
Published: (2012)

Molecular Analysis Of Cyp21 Gene In Patients Presenting With Ambiguous Genitalia.
by: Fuziah, M Z, et al.
Published: (2002)