Synthesis, Cholinesterase Inhibitory Activity And Molecular Docking Study Of Piperidone-Grafted Pyrimidine And Thiazolopyrimidine Derivatives

QR Code

Synthesis, Cholinesterase Inhibitory Activity And Molecular Docking Study Of Piperidone-Grafted Pyrimidine And Thiazolopyrimidine Derivatives

Alzheimer’s disease (AD) is the most common form of dementia among the elderly people. Based on the cholinergic hypothesis, loss of cholinergic neurons in AD patients’ brain leads to the decline of acetylcholine (ACh) neurotransmitter level and eventually causes severe dysfunctions in the cholinergi...

Full description

Bibliographic Details
Main Author:	Basiri, Alireza
Format:	Thesis
Language:	English
Published:	2014
Subjects:	RS1-441 Pharmacy and materia medica
Online Access:	http://eprints.usm.my/46371/ http://eprints.usm.my/46371/1/Alireza%20Basiri24.pdf

Similar Items

Synthesis, Characterization And Cholinesterase Inhibitory Activity Of Novel Piperidone Grafted Spiro Heterocycles
by: Yalda, Kia
Published: (2014)

Synthesis, Characterization And Cholinesterase Inhibitory Activity Of Novel Piperidone Grafted Spiro Heterocycles
by: Kia, Yalda
Published: (2014)

Evaluation Of Various Autodock Molecular Docking Programmes In Predicting The Neuraminidase Inhibitory Activity
by: Raime, Nurul Nadia
Published: (2015)

Bioactivity-Guided Isolation Of Ailanthus Malabarica For Toxoplasma Gondii And Cholinesterase Inhibitory Activities
by: Lee, Yuan-E
Published: (2017)

A Facile Ionic Liquid Promoted Synthesis, Cholinesterase Inhibitory Activity and Molecular Modeling Study of Novel Highly Functionalized Spiropyrrolidines
by: I. Almansour, Abdulrahman, et al.
Published: (2015)

An Expedient Synthesis, Acetylcholinesterase Inhibitory Activity, and Molecular Modeling Study of Highly Functionalized Hexahydro-1,6-naphthyridines
by: Almansour, Abdulrahman I., et al.
Published: (2015)

Synthesis of thymidine phosphorylase inhibitor based on quinoxaline derivatives and their molecular docking study
by: Noor Barak, Almandil, et al.
Published: (2019)

Antioxidant, cholinesterase and tyrosinase inhibitory activities of calophyllum symingtonianum and calophyllum depressinervosum
by: Aminudin, Nurul Iman, et al.
Published: (2015)

3,5-Bis(arylidene)-4-piperidones as potential dengue protease inhibitors
by: Osman, Hasnah, et al.
Published: (2017)

Cholinesterase inhibitory activity and chemical constituents of Stenochlaena palustris fronds at two different stages of maturity
by: Chear, Nelson Jeng Yeou, et al.
Published: (2016)

In vitro antioxidant, cholinesterase and tyrosinase inhibitory activities of calophyllum symingtonianum and calophyllum depressinervosum (guttiferae)
by: Aminudin, Nurul Iman, et al.
Published: (2015)

In-Vitro And Molecular Docking Studies Of Seven Selected Myrtaceae Plants For Neuraminidase Activity
by: Ali Abdusalsalam, Ashraf Ahmed
Published: (2016)

Cholinesterase inhibition activity and molecular docking study of eugenol derivatives
by: Khairunisa Mohd Zamli,, et al.
Published: (2021)

Anti-Cholinesterase Activity Of Malaysian Cassia Spp. And Its Bioactive Compound
by: Nurul Azman, Nurul Amira
Published: (2020)

Synthesis, Characterization And In Silico Studies Of Piperidone Derivatives: Dengue Protease Inhibitory Studies On Selected Compounds
by: Idris, Nor Hashima
Published: (2016)

Flavonoids-Rich Orthosiphon stamineus Extract as New Candidate for Angiotensin I-Converting Enzyme Inhibition: A Molecular Docking Study
by: Shafaei, Armaghan, et al.
Published: (2016)

Phytochemical, Bioassay And In Silico Studies On Anti - Cholinesterase Activities Of Cassia Timoriensis Dc. And Cassia Grandis L.F.
by: Al-Hawarri, Maram Basem Tawfiq
Published: (2022)

Molecular Docking Of Andrographolide To Rennin, HIV-Protease And Tyrosine Enzymes.
by: Kamaluddin, Achsanuddin, et al.
Published: (2003)

Synthesis And Application Of Molecularly Imprinted Solidphase Extraction For The Determination Of Terbutaline In Biological Matrices
by: Lim, Lay Lee
Published: (2006)

Development Of Electrospun Nanofibres Containing Ibuprofen Grafted Nanocrystalline Cellulose For Dermal Delivery
by: Ahmed Al-Mashhadani, Abdulsalam Qahtan
Published: (2022)

Synthesis Of Molecularly Imprinted Polymer For Selective Solid-Phase Extraction Of Salbutamol From Urine Samples
by: Lee, Wei Inn
Published: (2011)

In Vitro Antioxidant And Alpha-Glucosidase Inhibitory Activities Of Fruit Extracts From Seven Species Of Citrus
by: Henrietta, Ikwunne Helen
Published: (2018)

Synthesis, crystal structure and cholinesterase enzymes inhibitory activities of new pyridine alkaloid derivative
by: Ghalib, Gaza Murad, et al.
Published: (2015)

Docking Of Protein With Flavonoids.
by: Ng, Pei Ling, et al.
Published: (2003)

Synthesis, Characterisation And Evaluation Of Biocompatible Disulphide Cross-Linked Sodium Alginate Derivative Nanoparticles For Colon Targeted Drug Delivery
by: Ayub, Asila Dinie
Published: (2018)

Genotoxicity Assessment Of Standardised Root Extract Of Eurycoma Longifolia Jack And Synthesis Of Some Benzimidazole Derivatives And Evaluation Of Their Anti-Cancer Potential
by: Muttiah, Nithya Niranjini
Published: (2013)

Docking Of Different Enzymes With Quercetin
by: Ng, Pei Ling, et al.
Published: (2003)

Anti-Obesity Activity Of Pandanus Amaryllifolius Roxb. And Vitex Negundo Linn. : Isolated Compounds With PTP1B Inhibitory Effects
by: Rathnasamy, Selestin
Published: (2022)

Evaluation of α-Glucosidase Inhibitory Effect of 50% Ethanolic Standardized Extract of Orthosiphon stamineus Benth in Normal and Streptozotocin-Induced Diabetic Rats
by: Mohamed, Elsnoussi Ali, et al.
Published: (2015)

Design, Synthesis and Molecular Docking Studies of Some Novel Spiro Derivatives By 1,3-Cycloaddition Reaction
by: Hasmaruddin, Nurul Syazana, et al.
Published: (2016)

Application of group-based QSAR and molecular docking in the design of insulin-like growth factor antagonists
by: Abdullahi, Abubakar Danjuma, et al.
Published: (2015)

Pharmacokinetics And Metabolism Studies Of Antifilarial Drugs Derivatives Of Benzimidazole Carbamate
by: Ramanathan, Surash
Published: (1996)

Antihyprtensive Activity Of Para-substituted Clonidine Analogues And Their Acylated Derivatives
by: Lewis, Alan Martin
Published: (1994)

Modelling And Syntheses Of Vanillin Derivatives Targeting Influenza Virus Neuraminidase
by: Asaruddin, Mohd Razip
Published: (2016)

The Study Of Anticancer Properties Of Benzyl-O-Vanillin And Its Derivatives
by: Al-Mudaris, Zena A. Abdul Hameed
Published: (2011)

Molecular Dynamics Studies Of The Effects Of Neuraminidase Mutation On Oseltamivir Resistance
by: Muhammad Yusuf, Muhammad Yusuf
Published: (2015)

Molecular Modelling And Biological Evaluation Of Peptide Based Inhibitors For Dengue Virus
by: Ismail, Ahmad Ghazali
Published: (2021)

Studies On The Activity Of Isoniazid Derivatives And Their Combinations With Other Anti-TB Drugs On Mycobacterium Tuberculosis
by: Parumasivam, Thaigarajan
Published: (2012)

Theobromine-Based Synthetic Derivatives As Potential Inhibitors Of Dengue Virus Ii Serine Protease
by: Saqallah, Fadi Ghassan Mohammed
Published: (2023)

Synthesis, Characterization And Analgesic Activity Of Mitragynine Analogues
by: Ramlee, Nurul Izzati
Published: (2015)