Effect of vitex smilex on pregnant rats

The herbal plant Vitex smilex was evaluated for it effects on pregnant albino rats. 54 female rats were used for this study. The rats were divided into control group and treatment group. Extract of the plant was prepared with distilled water by using sohlet apparatus in pharmacology laboratories....

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Main Author: Nordin, Nor Hafizah Haji
Format: Article
Language:English
Published: Pusat Pengajian Sains Kesihatan, Universiti Sains Malaysia 2004
Subjects:
Online Access:http://eprints.usm.my/46257/
http://eprints.usm.my/46257/1/LI...Nor%20Hafizah%20Binti%20Haji%20Nordin...2004...-24%20pages.pdf
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author Nordin, Nor Hafizah Haji
author_facet Nordin, Nor Hafizah Haji
author_sort Nordin, Nor Hafizah Haji
building USM Institutional Repository
collection Online Access
description The herbal plant Vitex smilex was evaluated for it effects on pregnant albino rats. 54 female rats were used for this study. The rats were divided into control group and treatment group. Extract of the plant was prepared with distilled water by using sohlet apparatus in pharmacology laboratories. The plant extract was administered orally by means of a gavage from day 1 to 7 of pregnancy. Out of 12 rats in each group, 6 were laparotomized under ether anaesthesia on day 1 0 of pregnancy. Both the horns of uterus was observed for number of fetus or resorption site sites and allowed to full term pregnancy. Number of fetus was compared with the number of pups delivered. The remaining 6 rats were used for histological study to confirm the activity of the extract. Result of the study showed that aqueous extract of Vitex smilex did not show efficacy as an antifertility agent. However, late resorbtion was observed in rat, which treated with 1 Omg/kg and 1 OOmg/kg of Vitex smilex extract.
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spelling usm-462572020-02-18T08:06:05Z http://eprints.usm.my/46257/ Effect of vitex smilex on pregnant rats Nordin, Nor Hafizah Haji RM Therapeutics. Pharmacology The herbal plant Vitex smilex was evaluated for it effects on pregnant albino rats. 54 female rats were used for this study. The rats were divided into control group and treatment group. Extract of the plant was prepared with distilled water by using sohlet apparatus in pharmacology laboratories. The plant extract was administered orally by means of a gavage from day 1 to 7 of pregnancy. Out of 12 rats in each group, 6 were laparotomized under ether anaesthesia on day 1 0 of pregnancy. Both the horns of uterus was observed for number of fetus or resorption site sites and allowed to full term pregnancy. Number of fetus was compared with the number of pups delivered. The remaining 6 rats were used for histological study to confirm the activity of the extract. Result of the study showed that aqueous extract of Vitex smilex did not show efficacy as an antifertility agent. However, late resorbtion was observed in rat, which treated with 1 Omg/kg and 1 OOmg/kg of Vitex smilex extract. Pusat Pengajian Sains Kesihatan, Universiti Sains Malaysia 2004 Article NonPeerReviewed application/pdf en http://eprints.usm.my/46257/1/LI...Nor%20Hafizah%20Binti%20Haji%20Nordin...2004...-24%20pages.pdf Nordin, Nor Hafizah Haji (2004) Effect of vitex smilex on pregnant rats. Effect of vitex smilex on pregnant rats. (Submitted)
spellingShingle RM Therapeutics. Pharmacology
Nordin, Nor Hafizah Haji
Effect of vitex smilex on pregnant rats
title Effect of vitex smilex on pregnant rats
title_full Effect of vitex smilex on pregnant rats
title_fullStr Effect of vitex smilex on pregnant rats
title_full_unstemmed Effect of vitex smilex on pregnant rats
title_short Effect of vitex smilex on pregnant rats
title_sort effect of vitex smilex on pregnant rats
topic RM Therapeutics. Pharmacology
url http://eprints.usm.my/46257/
http://eprints.usm.my/46257/1/LI...Nor%20Hafizah%20Binti%20Haji%20Nordin...2004...-24%20pages.pdf