The Effect Of Standardized Extract Of Eurycoma Longifolia On Phase I And Phase Ii Metabolic Pathways And Rosiglitazone Pharmacokinetics
The belief that natural products are safer than synthetic drugs has led to the dramatic growth in herbal medicine usage. However, herbal preparations have the potential to cause toxicity, herb-drug interactions and may affect the drug therapeutic effects. Eurycoma longifolia Jack (Tongkat Ali) has b...
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| Format: | Thesis |
| Language: | English |
| Published: |
2013
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| Online Access: | http://eprints.usm.my/46198/ http://eprints.usm.my/46198/1/Purwantiningsih24.pdf |
| _version_ | 1848880541165682688 |
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| author | Purwantiningsih, Purwantiningsih |
| author_facet | Purwantiningsih, Purwantiningsih |
| author_sort | Purwantiningsih, Purwantiningsih |
| building | USM Institutional Repository |
| collection | Online Access |
| description | The belief that natural products are safer than synthetic drugs has led to the dramatic growth in herbal medicine usage. However, herbal preparations have the potential to cause toxicity, herb-drug interactions and may affect the drug therapeutic effects. Eurycoma longifolia Jack (Tongkat Ali) has been widely used by the local population as an aphrodisiac, and contains many chemical constituents which should be monitored for herb-drug interactions. Therefore, study about the effects of the standardized extract of E. longifolia on the pharmacological profile involving metabolism phase I and II, and the pharmacokinetics of rosiglitazone needs to be conducted to ensure the efficacy and safety of use. |
| first_indexed | 2025-11-15T18:04:46Z |
| format | Thesis |
| id | usm-46198 |
| institution | Universiti Sains Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T18:04:46Z |
| publishDate | 2013 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | usm-461982020-02-13T04:22:10Z http://eprints.usm.my/46198/ The Effect Of Standardized Extract Of Eurycoma Longifolia On Phase I And Phase Ii Metabolic Pathways And Rosiglitazone Pharmacokinetics Purwantiningsih, Purwantiningsih RS1-441 Pharmacy and materia medica The belief that natural products are safer than synthetic drugs has led to the dramatic growth in herbal medicine usage. However, herbal preparations have the potential to cause toxicity, herb-drug interactions and may affect the drug therapeutic effects. Eurycoma longifolia Jack (Tongkat Ali) has been widely used by the local population as an aphrodisiac, and contains many chemical constituents which should be monitored for herb-drug interactions. Therefore, study about the effects of the standardized extract of E. longifolia on the pharmacological profile involving metabolism phase I and II, and the pharmacokinetics of rosiglitazone needs to be conducted to ensure the efficacy and safety of use. 2013-12 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/46198/1/Purwantiningsih24.pdf Purwantiningsih, Purwantiningsih (2013) The Effect Of Standardized Extract Of Eurycoma Longifolia On Phase I And Phase Ii Metabolic Pathways And Rosiglitazone Pharmacokinetics. PhD thesis, Universiti Sains Malaysia. |
| spellingShingle | RS1-441 Pharmacy and materia medica Purwantiningsih, Purwantiningsih The Effect Of Standardized Extract Of Eurycoma Longifolia On Phase I And Phase Ii Metabolic Pathways And Rosiglitazone Pharmacokinetics |
| title | The Effect Of Standardized Extract Of Eurycoma Longifolia On Phase I And Phase Ii Metabolic Pathways And Rosiglitazone Pharmacokinetics |
| title_full | The Effect Of Standardized Extract Of Eurycoma Longifolia On Phase I And Phase Ii Metabolic Pathways And Rosiglitazone Pharmacokinetics |
| title_fullStr | The Effect Of Standardized Extract Of Eurycoma Longifolia On Phase I And Phase Ii Metabolic Pathways And Rosiglitazone Pharmacokinetics |
| title_full_unstemmed | The Effect Of Standardized Extract Of Eurycoma Longifolia On Phase I And Phase Ii Metabolic Pathways And Rosiglitazone Pharmacokinetics |
| title_short | The Effect Of Standardized Extract Of Eurycoma Longifolia On Phase I And Phase Ii Metabolic Pathways And Rosiglitazone Pharmacokinetics |
| title_sort | effect of standardized extract of eurycoma longifolia on phase i and phase ii metabolic pathways and rosiglitazone pharmacokinetics |
| topic | RS1-441 Pharmacy and materia medica |
| url | http://eprints.usm.my/46198/ http://eprints.usm.my/46198/1/Purwantiningsih24.pdf |