Outcomes of transcatheter device closure in atrial septal defect secundum in Kelantan : a single center experience

Background – To look at demographic, procedural and clinical characteristic of patients with atrial septal defect secundum (ASDs) who underwent transcatheter device closure, median survival time to ASDs closure and its outcome in pediatric and adult patients. Material and methods – This retrospecti...

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Main Author: Niza@Nizal, Hanif Mohd @Mohd
Format: Thesis
Language:English
Published: 2018
Subjects:
Online Access:http://eprints.usm.my/45902/
http://eprints.usm.my/45902/1/Dr.%20Hanif%20Mohd%20Niza%40Mohd%20Nizal-24%20pages.pdf
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author Niza@Nizal, Hanif Mohd @Mohd
author_facet Niza@Nizal, Hanif Mohd @Mohd
author_sort Niza@Nizal, Hanif Mohd @Mohd
building USM Institutional Repository
collection Online Access
description Background – To look at demographic, procedural and clinical characteristic of patients with atrial septal defect secundum (ASDs) who underwent transcatheter device closure, median survival time to ASDs closure and its outcome in pediatric and adult patients. Material and methods – This retrospective study was conducted from January 2005 to December 2015 in patients with ASDs underwent transcatheter device closure at Hospital Universiti Sains Malaysia. Results – 73 patients (42 children and 31 adults) with 75% of female predominance. Median age at diagnosis was 8 years old and median age at procedure was 15 years old. 25% of patients are symptomatic on procedural day, with reduced effort tolerance being the most reported symptoms (83%). Majority of patients had large ASDs, with median of 22mm (7mm – 33.6mm), with 60% of patients had rim deficiency. Median survival time of ASDs closure in pediatric and adult age group were 3 years and 2 years respectively. Success rate was 90.4%. There was 5.5% residual shunt immediately after procedure, with 100% complete resolution at the end of follow-up at 2 years. Conclusions – Transcatheter device closure is safe and effective in large ASDs population with rim deficiency, with comparable outcome and minimal serious complication.
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spelling usm-459022020-01-16T07:44:57Z http://eprints.usm.my/45902/ Outcomes of transcatheter device closure in atrial septal defect secundum in Kelantan : a single center experience Niza@Nizal, Hanif Mohd @Mohd RC666-701 Diseases of the circulatory (Cardiovascular) system Background – To look at demographic, procedural and clinical characteristic of patients with atrial septal defect secundum (ASDs) who underwent transcatheter device closure, median survival time to ASDs closure and its outcome in pediatric and adult patients. Material and methods – This retrospective study was conducted from January 2005 to December 2015 in patients with ASDs underwent transcatheter device closure at Hospital Universiti Sains Malaysia. Results – 73 patients (42 children and 31 adults) with 75% of female predominance. Median age at diagnosis was 8 years old and median age at procedure was 15 years old. 25% of patients are symptomatic on procedural day, with reduced effort tolerance being the most reported symptoms (83%). Majority of patients had large ASDs, with median of 22mm (7mm – 33.6mm), with 60% of patients had rim deficiency. Median survival time of ASDs closure in pediatric and adult age group were 3 years and 2 years respectively. Success rate was 90.4%. There was 5.5% residual shunt immediately after procedure, with 100% complete resolution at the end of follow-up at 2 years. Conclusions – Transcatheter device closure is safe and effective in large ASDs population with rim deficiency, with comparable outcome and minimal serious complication. 2018 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/45902/1/Dr.%20Hanif%20Mohd%20Niza%40Mohd%20Nizal-24%20pages.pdf Niza@Nizal, Hanif Mohd @Mohd (2018) Outcomes of transcatheter device closure in atrial septal defect secundum in Kelantan : a single center experience. Masters thesis, Universiti Sains Malaysia.
spellingShingle RC666-701 Diseases of the circulatory (Cardiovascular) system
Niza@Nizal, Hanif Mohd @Mohd
Outcomes of transcatheter device closure in atrial septal defect secundum in Kelantan : a single center experience
title Outcomes of transcatheter device closure in atrial septal defect secundum in Kelantan : a single center experience
title_full Outcomes of transcatheter device closure in atrial septal defect secundum in Kelantan : a single center experience
title_fullStr Outcomes of transcatheter device closure in atrial septal defect secundum in Kelantan : a single center experience
title_full_unstemmed Outcomes of transcatheter device closure in atrial septal defect secundum in Kelantan : a single center experience
title_short Outcomes of transcatheter device closure in atrial septal defect secundum in Kelantan : a single center experience
title_sort outcomes of transcatheter device closure in atrial septal defect secundum in kelantan : a single center experience
topic RC666-701 Diseases of the circulatory (Cardiovascular) system
url http://eprints.usm.my/45902/
http://eprints.usm.my/45902/1/Dr.%20Hanif%20Mohd%20Niza%40Mohd%20Nizal-24%20pages.pdf