Intraoperative crush cytology in the diagnosis of neurosurgical cases
Intraoperative cytologic smears in neurosurgery are easy to perform and inexpensive and permit reasonably high diagnostic accuracy. Even very tiny specimens, especially of soft consistency are suitable for this technique, which is extremely important in operation of tumours localized in functiona...
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| Format: | Article |
| Language: | English |
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Pusat Pengajian Sains Perubatan, Universiti Sains Malaysia
2005
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| Online Access: | http://eprints.usm.my/45863/ http://eprints.usm.my/45863/1/GP...Intraoperative%20Crush%20Cytology%20In%20The%20Diagnosis%20Of%20Neurosurgical%20Cases...2005...-OCR.pdf |
| _version_ | 1848880446956371968 |
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| author | Madhavan, Madhavan Singh, Gurjeet Kaur d/o Chatar P, Jain George |
| author_facet | Madhavan, Madhavan Singh, Gurjeet Kaur d/o Chatar P, Jain George |
| author_sort | Madhavan, Madhavan |
| building | USM Institutional Repository |
| collection | Online Access |
| description | Intraoperative cytologic smears in neurosurgery are easy to perform and inexpensive and permit
reasonably high diagnostic accuracy.
Even very tiny specimens, especially of soft consistency are suitable for this technique, which is
extremely important in operation of tumours localized in functionally important brain areas.
The cytologic diagnosis could be made based on the presence of characteristic
cytomorphological features. Very high accuracy can be archived in certain tumours like nerve
sheath tumour, germinoma, meningioma, metastasis, grade II astrocytoma, pituitary adenoma
and oligidendroglioma. However, the accuracy is low in high grade glioma, medulloblastoma and
ependymoma. In the absence of their diagnostic cytomorphological features, the correlation with
clinicoradiological features might help in arriving at the correct diagnostic and increase their
diagnostic accuracy.
Further studies involving more number of cases is needed to find out the value of crush cytology
in diagnosing the rare tumours and inflammatory lesions.
In cytology examination, presence of pure normal glial tissue has high negative predictive value.
This helps in guidance during targeting the lesions including steriotactic biopsy and also during
the resection of infiltrative lesions for definition of tumour margins. |
| first_indexed | 2025-11-15T18:03:16Z |
| format | Article |
| id | usm-45863 |
| institution | Universiti Sains Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T18:03:16Z |
| publishDate | 2005 |
| publisher | Pusat Pengajian Sains Perubatan, Universiti Sains Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | usm-458632019-12-22T08:18:21Z http://eprints.usm.my/45863/ Intraoperative crush cytology in the diagnosis of neurosurgical cases Madhavan, Madhavan Singh, Gurjeet Kaur d/o Chatar P, Jain George RC Internal medicine Intraoperative cytologic smears in neurosurgery are easy to perform and inexpensive and permit reasonably high diagnostic accuracy. Even very tiny specimens, especially of soft consistency are suitable for this technique, which is extremely important in operation of tumours localized in functionally important brain areas. The cytologic diagnosis could be made based on the presence of characteristic cytomorphological features. Very high accuracy can be archived in certain tumours like nerve sheath tumour, germinoma, meningioma, metastasis, grade II astrocytoma, pituitary adenoma and oligidendroglioma. However, the accuracy is low in high grade glioma, medulloblastoma and ependymoma. In the absence of their diagnostic cytomorphological features, the correlation with clinicoradiological features might help in arriving at the correct diagnostic and increase their diagnostic accuracy. Further studies involving more number of cases is needed to find out the value of crush cytology in diagnosing the rare tumours and inflammatory lesions. In cytology examination, presence of pure normal glial tissue has high negative predictive value. This helps in guidance during targeting the lesions including steriotactic biopsy and also during the resection of infiltrative lesions for definition of tumour margins. Pusat Pengajian Sains Perubatan, Universiti Sains Malaysia 2005 Article NonPeerReviewed application/pdf en http://eprints.usm.my/45863/1/GP...Intraoperative%20Crush%20Cytology%20In%20The%20Diagnosis%20Of%20Neurosurgical%20Cases...2005...-OCR.pdf Madhavan, Madhavan and Singh, Gurjeet Kaur d/o Chatar and P, Jain George (2005) Intraoperative crush cytology in the diagnosis of neurosurgical cases. Intraoperative crush cytology in the diagnosis of neurosurgical cases. (Submitted) |
| spellingShingle | RC Internal medicine Madhavan, Madhavan Singh, Gurjeet Kaur d/o Chatar P, Jain George Intraoperative crush cytology in the diagnosis of neurosurgical cases |
| title | Intraoperative crush cytology in the diagnosis of neurosurgical cases |
| title_full | Intraoperative crush cytology in the diagnosis of neurosurgical cases |
| title_fullStr | Intraoperative crush cytology in the diagnosis of neurosurgical cases |
| title_full_unstemmed | Intraoperative crush cytology in the diagnosis of neurosurgical cases |
| title_short | Intraoperative crush cytology in the diagnosis of neurosurgical cases |
| title_sort | intraoperative crush cytology in the diagnosis of neurosurgical cases |
| topic | RC Internal medicine |
| url | http://eprints.usm.my/45863/ http://eprints.usm.my/45863/1/GP...Intraoperative%20Crush%20Cytology%20In%20The%20Diagnosis%20Of%20Neurosurgical%20Cases...2005...-OCR.pdf |