Enhanced Production Of Poly (3-Hydroxybutyrate-Co-4-Hydroxybutyrate) With High 4hb Unit Composition Using Transformant Cupriavidus sp.USMAA1020
Poly(3-hydroxybutyrate-co-4-hydroxybutyrate) [P(3HB-co-4HB)] copolymer is one of emerging biopolymer which possess suitable properties to be applied in medical applications. P(3HB-co-4HB) with high 4HB unit is favorable as this enhance the biocompatibility and mechanical properties of this copolymer...
| Main Author: | |
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| Format: | Thesis |
| Language: | English |
| Published: |
2017
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| Subjects: | |
| Online Access: | http://eprints.usm.my/45453/ http://eprints.usm.my/45453/1/NORHAFINI%20HAMBALI.pdf |
| _version_ | 1848880336091480064 |
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| author | Hambali, Norhafini |
| author_facet | Hambali, Norhafini |
| author_sort | Hambali, Norhafini |
| building | USM Institutional Repository |
| collection | Online Access |
| description | Poly(3-hydroxybutyrate-co-4-hydroxybutyrate) [P(3HB-co-4HB)] copolymer is one of emerging biopolymer which possess suitable properties to be applied in medical applications. P(3HB-co-4HB) with high 4HB unit is favorable as this enhance the biocompatibility and mechanical properties of this copolymer as implantable and absorbable biomaterial. However, biosynthesis of P(3HB-co-4HB) in single-stage cultivation produces low 4HB unit composition with low productivity. Cupriavidus sp. USMAA1020, a bacterium isolated from Malaysian environment, was capable to synthesize P(3HB-co-4HB) with different 4HB unit compositions but only to a maximum of 70 mol% through single-stage cultivation. |
| first_indexed | 2025-11-15T18:01:30Z |
| format | Thesis |
| id | usm-45453 |
| institution | Universiti Sains Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T18:01:30Z |
| publishDate | 2017 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | usm-454532019-09-18T01:04:07Z http://eprints.usm.my/45453/ Enhanced Production Of Poly (3-Hydroxybutyrate-Co-4-Hydroxybutyrate) With High 4hb Unit Composition Using Transformant Cupriavidus sp.USMAA1020 Hambali, Norhafini RS200-201 Pharmaceutical dosage forms Poly(3-hydroxybutyrate-co-4-hydroxybutyrate) [P(3HB-co-4HB)] copolymer is one of emerging biopolymer which possess suitable properties to be applied in medical applications. P(3HB-co-4HB) with high 4HB unit is favorable as this enhance the biocompatibility and mechanical properties of this copolymer as implantable and absorbable biomaterial. However, biosynthesis of P(3HB-co-4HB) in single-stage cultivation produces low 4HB unit composition with low productivity. Cupriavidus sp. USMAA1020, a bacterium isolated from Malaysian environment, was capable to synthesize P(3HB-co-4HB) with different 4HB unit compositions but only to a maximum of 70 mol% through single-stage cultivation. 2017-03 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/45453/1/NORHAFINI%20HAMBALI.pdf Hambali, Norhafini (2017) Enhanced Production Of Poly (3-Hydroxybutyrate-Co-4-Hydroxybutyrate) With High 4hb Unit Composition Using Transformant Cupriavidus sp.USMAA1020. Masters thesis, Universiti Sains Malaysia. |
| spellingShingle | RS200-201 Pharmaceutical dosage forms Hambali, Norhafini Enhanced Production Of Poly (3-Hydroxybutyrate-Co-4-Hydroxybutyrate) With High 4hb Unit Composition Using Transformant Cupriavidus sp.USMAA1020 |
| title | Enhanced Production Of Poly (3-Hydroxybutyrate-Co-4-Hydroxybutyrate) With High 4hb Unit Composition Using Transformant Cupriavidus sp.USMAA1020 |
| title_full | Enhanced Production Of Poly (3-Hydroxybutyrate-Co-4-Hydroxybutyrate) With High 4hb Unit Composition Using Transformant Cupriavidus sp.USMAA1020 |
| title_fullStr | Enhanced Production Of Poly (3-Hydroxybutyrate-Co-4-Hydroxybutyrate) With High 4hb Unit Composition Using Transformant Cupriavidus sp.USMAA1020 |
| title_full_unstemmed | Enhanced Production Of Poly (3-Hydroxybutyrate-Co-4-Hydroxybutyrate) With High 4hb Unit Composition Using Transformant Cupriavidus sp.USMAA1020 |
| title_short | Enhanced Production Of Poly (3-Hydroxybutyrate-Co-4-Hydroxybutyrate) With High 4hb Unit Composition Using Transformant Cupriavidus sp.USMAA1020 |
| title_sort | enhanced production of poly (3-hydroxybutyrate-co-4-hydroxybutyrate) with high 4hb unit composition using transformant cupriavidus sp.usmaa1020 |
| topic | RS200-201 Pharmaceutical dosage forms |
| url | http://eprints.usm.my/45453/ http://eprints.usm.my/45453/1/NORHAFINI%20HAMBALI.pdf |