Generation And Characterisation Of RNA Aptamers Against ESAT6 Protein From Mycobacterium Tuberculosis
Aptamers are chemical ligands made up of short nucleotides sequences that are able to bind to target proteins with high affinity and specificity. They are generated using a process called Systemic Evolution of Ligands via Exponential Enrichment (SELEX). Due to their chemical stability and high speci...
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| Format: | Thesis |
| Language: | English |
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2017
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| Online Access: | http://eprints.usm.my/45354/ http://eprints.usm.my/45354/1/BAKHTIAR%20AFFENDI%20BUKARI.pdf |
| _version_ | 1848880306650611712 |
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| author | Bukari, Bakhtiar Affendi |
| author_facet | Bukari, Bakhtiar Affendi |
| author_sort | Bukari, Bakhtiar Affendi |
| building | USM Institutional Repository |
| collection | Online Access |
| description | Aptamers are chemical ligands made up of short nucleotides sequences that are able to bind to target proteins with high affinity and specificity. They are generated using a process called Systemic Evolution of Ligands via Exponential Enrichment (SELEX). Due to their chemical stability and high specificity against the target, aptamers have the potential to become very useful biological tools. The 6 kDa Early Secretory Antigenic Target, or ESAT6, is a secretory protein produced by Mycobacterium tuberculosis and is thought to be a major player in mycobacterial pathogenesis. |
| first_indexed | 2025-11-15T18:01:02Z |
| format | Thesis |
| id | usm-45354 |
| institution | Universiti Sains Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T18:01:02Z |
| publishDate | 2017 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | usm-453542019-09-10T02:42:04Z http://eprints.usm.my/45354/ Generation And Characterisation Of RNA Aptamers Against ESAT6 Protein From Mycobacterium Tuberculosis Bukari, Bakhtiar Affendi R735-854 Medical education. Medical schools. Research Aptamers are chemical ligands made up of short nucleotides sequences that are able to bind to target proteins with high affinity and specificity. They are generated using a process called Systemic Evolution of Ligands via Exponential Enrichment (SELEX). Due to their chemical stability and high specificity against the target, aptamers have the potential to become very useful biological tools. The 6 kDa Early Secretory Antigenic Target, or ESAT6, is a secretory protein produced by Mycobacterium tuberculosis and is thought to be a major player in mycobacterial pathogenesis. 2017-07 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/45354/1/BAKHTIAR%20AFFENDI%20BUKARI.pdf Bukari, Bakhtiar Affendi (2017) Generation And Characterisation Of RNA Aptamers Against ESAT6 Protein From Mycobacterium Tuberculosis. Masters thesis, Universiti Sains Malaysia. |
| spellingShingle | R735-854 Medical education. Medical schools. Research Bukari, Bakhtiar Affendi Generation And Characterisation Of RNA Aptamers Against ESAT6 Protein From Mycobacterium Tuberculosis |
| title | Generation And Characterisation Of RNA Aptamers Against ESAT6 Protein From Mycobacterium Tuberculosis |
| title_full | Generation And Characterisation Of RNA Aptamers Against ESAT6 Protein From Mycobacterium Tuberculosis |
| title_fullStr | Generation And Characterisation Of RNA Aptamers Against ESAT6 Protein From Mycobacterium Tuberculosis |
| title_full_unstemmed | Generation And Characterisation Of RNA Aptamers Against ESAT6 Protein From Mycobacterium Tuberculosis |
| title_short | Generation And Characterisation Of RNA Aptamers Against ESAT6 Protein From Mycobacterium Tuberculosis |
| title_sort | generation and characterisation of rna aptamers against esat6 protein from mycobacterium tuberculosis |
| topic | R735-854 Medical education. Medical schools. Research |
| url | http://eprints.usm.my/45354/ http://eprints.usm.my/45354/1/BAKHTIAR%20AFFENDI%20BUKARI.pdf |